G0I3W0 (G0I3W0_CORPS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase [NADP] EMBL AEK91791.1

Gene names

Name:	icd EMBL AEK91791.1
ORF Names:	CpPAT10_0461 EMBL AEK91791.1

Organism

Corynebacterium pseudotuberculosis PAT10 EMBL AEK91791.1

Taxonomic identifier

935298 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium pseudotuberculosis

Protein attributes

Sequence length	736 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	130 – 137	8	Substrate binding By similarity PIRSR PIRSR009407-2
Sites
	Metal binding	345	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	543	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	547	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Binding site	143	1	Substrate By similarity PIRSR PIRSR009407-2
	Binding site	542	1	Substrate By similarity PIRSR PIRSR009407-2
	Site	252	1	Critical for catalysis By similarity PIRSR PIRSR009407-1
	Site	415	1	Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

	Sequence		Length	Mass (Da)
	G0I3W0 [UniParc]. Last modified October 19, 2011. Version 1. Checksum: 39771BB46760A831	FASTA	736	79,816
	10 20 30 40 50 60 MAKIIYTRTD EAPLLATYSL KPVVEAFAST AGIEVETRDI SLAGRILSQF PEFLTEDQKV 70 80 90 100 110 120 DDALAELGEL AKTPEANIIK LPNISASVPQ LKAAVTELQS QGYKLPNYPD SPSTEEEKDI 130 140 150 160 170 180 RARYDAVKGS AVNPVLREGN SDRRAPIAVK NFAKKHPHRM GAWSADSKTN VVTMESNDFR 190 200 210 220 230 240 HNEKSVIMPD NDTLTIKLVT DNGEKVLKDG LKVLKGEVVD GTFISARALD EFLADQVKRA 250 260 270 280 290 300 KDEGVLFSAH LKATMMKVSD PIIFGHVVRA YFADVFAKYG EQLEAAGLNG ENGLAAIYSG 310 320 330 340 350 360 LESLPNGAEI KAAFDEALES GADIAMVNSA KGITNLHVPS DVIIDASMPA MIRTSGHMWN 370 380 390 400 410 420 KNDEEQDTLA VIPDSSYAGV YQTVIADCKK NGAFDPTTMG TVPNVGLMAQ KAEEYGSHDK 430 440 450 460 470 480 TFKIEANGTV QVVSSAGEVL IEHNVEAGDI WRACQAKDAP IQDWVKLAVT RSRLSGMPAV 490 500 510 520 530 540 FWLDPERAHD RNLAALVEKY LADHDTEGLD IHIMSPVEAT QFSIDRIRRG EDTISVTGNV 550 560 570 580 590 600 LRDYNTDLFP ILELGTSAKM LSVVPLMAGG GLFETGAGGS APKHVQQLVE ENHLRWDSLG 610 620 630 640 650 660 EFLALAESLR HFANTEGNTK AGILADTLDR ATETLLNEGY SPSRKAGEID NRGSHFFLTK 670 680 690 700 710 720 FWAKELSIQS EDADLAATFT PVAEALETHS EDIADALLAV QGAPADLGGY YHPDDAKTTA 730 VMRPVASYND IISSIK

References

[1]

"Whole-Genome Sequence of Corynebacterium pseudotuberculosis PAT10 Strain Isolated from Sheep in Patagonia, Argentina." Cerdeira L.T., Pinto A.C., Schneider M.P., de Almeida S.S., Dos Santos A.R., Barbosa E.G., Ali A., Barbosa M.S., Carneiro A.R., Ramos R.T., de Oliveira R.S., Barh D., Barve N., Zambare V., Belchior S.E., Guimaraes L.C., de Castro Soares S., Dorella F.A. , Rocha F.S., de Abreu V.A., Tauch A., Trost E., Miyoshi A., Azevedo V., Silva A. J. Bacteriol. 193:6420-6421(2011) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PAT10 EMBL AEK91791.1.

[2]

Rede Paraense de Genomica e Proteomica (RPGP) Cerdeira L., Schneider M.P.C., Barbosa M.S., Ramos R.T.J., Carneiro A.R., Santos R.S., Lima M., DAFonseca V., Almeida S.S., Santos A.R., Soares S.C., Pinto A.C., Ali A., Barbosa E., Dorella F.A., Rocha F.S., Guimaraes L.G., Belchior S.B. , Ghosh P., Zambare V., Barve N., Tiwari S., Barh D., Miyoshi A., Azevedo V., Silva A. Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: PAT10 EMBL AEK91791.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002924 Genomic DNA. Translation: AEK91791.1.
RefSeq	YP_005689909.1. NC_017305.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEK91791; AEK91791; CpPAT10_0461.
GeneID	12294511.
KEGG	cpz:CpPAT10_0461.
Phylogenomic databases
KO	K00031.
Family and domain databases
Gene3D	3.40.718.10. 3 hits.
InterPro	IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
Pfam	PF03971. IDH. 1 hit. [Graphical view]
PIRSF	PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMs	TIGR00178. monomer_idh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G0I3W0_CORPS

Accession

Primary (citable) accession number: G0I3W0

Entry history

Integrated into UniProtKB/TrEMBL:	October 19, 2011
Last sequence update:	October 19, 2011
Last modified:	April 3, 2013
This is version 11 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)