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G0I3W0

- G0I3W0_CORPS

UniProt

G0I3W0 - G0I3W0_CORPS

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Protein
Submitted name:

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Corynebacterium pseudotuberculosis PAT10
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

Cofactori

Note: Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei252 – 2521Critical for catalysisUniRule annotation
Metal bindingi345 – 3451Magnesium or manganeseUniRule annotation
Sitei415 – 4151Critical for catalysisUniRule annotation
Binding sitei542 – 5421SubstrateUniRule annotation
Metal bindingi543 – 5431Magnesium or manganeseUniRule annotation
Metal bindingi547 – 5471Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciCPSE935298:GLC1-479-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase [NADP]Imported
Gene namesi
Name:icdImported
ORF Names:CpPAT10_0461Imported
OrganismiCorynebacterium pseudotuberculosis PAT10Imported
Taxonomic identifieri935298 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
ProteomesiUP000000873: Chromosome

Family & Domainsi

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

G0I3W0-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MAKIIYTRTD EAPLLATYSL KPVVEAFAST AGIEVETRDI SLAGRILSQF
60 70 80 90 100
PEFLTEDQKV DDALAELGEL AKTPEANIIK LPNISASVPQ LKAAVTELQS
110 120 130 140 150
QGYKLPNYPD SPSTEEEKDI RARYDAVKGS AVNPVLREGN SDRRAPIAVK
160 170 180 190 200
NFAKKHPHRM GAWSADSKTN VVTMESNDFR HNEKSVIMPD NDTLTIKLVT
210 220 230 240 250
DNGEKVLKDG LKVLKGEVVD GTFISARALD EFLADQVKRA KDEGVLFSAH
260 270 280 290 300
LKATMMKVSD PIIFGHVVRA YFADVFAKYG EQLEAAGLNG ENGLAAIYSG
310 320 330 340 350
LESLPNGAEI KAAFDEALES GADIAMVNSA KGITNLHVPS DVIIDASMPA
360 370 380 390 400
MIRTSGHMWN KNDEEQDTLA VIPDSSYAGV YQTVIADCKK NGAFDPTTMG
410 420 430 440 450
TVPNVGLMAQ KAEEYGSHDK TFKIEANGTV QVVSSAGEVL IEHNVEAGDI
460 470 480 490 500
WRACQAKDAP IQDWVKLAVT RSRLSGMPAV FWLDPERAHD RNLAALVEKY
510 520 530 540 550
LADHDTEGLD IHIMSPVEAT QFSIDRIRRG EDTISVTGNV LRDYNTDLFP
560 570 580 590 600
ILELGTSAKM LSVVPLMAGG GLFETGAGGS APKHVQQLVE ENHLRWDSLG
610 620 630 640 650
EFLALAESLR HFANTEGNTK AGILADTLDR ATETLLNEGY SPSRKAGEID
660 670 680 690 700
NRGSHFFLTK FWAKELSIQS EDADLAATFT PVAEALETHS EDIADALLAV
710 720 730
QGAPADLGGY YHPDDAKTTA VMRPVASYND IISSIK
Length:736
Mass (Da):79,816
Last modified:October 19, 2011 - v1
Checksum:i39771BB46760A831
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002924 Genomic DNA. Translation: AEK91791.1.
RefSeqiYP_005689909.1. NC_017305.1.

Genome annotation databases

EnsemblBacteriaiAEK91791; AEK91791; CpPAT10_0461.
GeneIDi12294511.
KEGGicpz:CpPAT10_0461.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002924 Genomic DNA. Translation: AEK91791.1 .
RefSeqi YP_005689909.1. NC_017305.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEK91791 ; AEK91791 ; CpPAT10_0461 .
GeneIDi 12294511.
KEGGi cpz:CpPAT10_0461.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci CPSE935298:GLC1-479-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PAT10Imported.

Entry informationi

Entry nameiG0I3W0_CORPS
AccessioniPrimary (citable) accession number: G0I3W0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 26, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3