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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Thermococcus sp. (strain CGMCC 1.5172 / 4557)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationImported
Biological processCarbon dioxide fixationUniRule annotation
LigandMagnesiumUniRule annotation, PyruvateImported

Enzyme and pathway databases

BioCyciTSP1042877:G1GZH-2139-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:GQS_10630Imported
OrganismiThermococcus sp. (strain CGMCC 1.5172 / 4557)Imported
Taxonomic identifieri1042877 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000000874 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi1042877.GQS_10630

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04435 Archaea
COG1892 LUCA
KOiK01595
OMAiPAMNYGL
OrthoDBiPOG093Z01LI

Family and domain databases

HAMAPiMF_01904 PEPcase_type2, 1 hit
InterProiView protein in InterPro
IPR007566 PEP_COase_arc-type
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PfamiView protein in Pfam
PF14010 PEPcase_2, 1 hit
PIRSFiPIRSF006677 UCP006677, 1 hit
SUPFAMiSSF51621 SSF51621, 1 hit
TIGRFAMsiTIGR02751 PEPCase_arch, 1 hit

Sequencei

Sequence statusi: Complete.

G0HPP9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIPRTMSTQH PDNVFIPFFA GSPTMGGEDE VIEAFYAFSV LGIDEQMWDF
60 70 80 90 100
EGKEVDEFVV KKLFERYGYF FKRKKLGEEL RLTPRVPNPS VERAEAKLLL
110 120 130 140 150
ETLEAIPRSA DYARLFYGEE LPPIFEVILP MTTSSQELNR VYELYRHYIA
160 170 180 190 200
GKQYKRVHDI KLHEWIGEFY PSEIGVIPLF ESREAILSAA DIVREYLGGK
210 220 230 240 250
EVEYQRVFLA RSDPAMNYGL ISAVLYDKLA LFELQGLEEE LGIPIYPIIG
260 270 280 290 300
VGGAPFRGHF TPENVEGVLA EYPSVQTFTI QSSFKYDRTP KDVIRAVERI
310 320 330 340 350
RESKRGKALP VPEEAFEILK KYEARYSEEL RALAPFIREV AKFVPSRRRR
360 370 380 390 400
KLHIGLFGYS REVNGSALPR AIKFTASLYS LGIPPELLGL SALSEKELEF
410 420 430 440 450
LGDYYLDLYR DIEFAFRYFN PKAAERFPFL KPLAKMARDY ERDERHGEIT
460 470
SRILAGELSS ELIVEAAGIR GFLG
Length:474
Mass (Da):54,418
Last modified:October 19, 2011 - v1
Checksum:iEAE01A04E1D9ACE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002920 Genomic DNA Translation: AEK74019.1
RefSeqiWP_014013701.1, NC_015865.1

Genome annotation databases

EnsemblBacteriaiAEK74019; AEK74019; GQS_10630
GeneIDi11016810
KEGGithe:GQS_10630
PATRICifig|1042877.9.peg.2079

Similar proteinsi

Entry informationi

Entry nameiG0HPP9_THES4
AccessioniPrimary (citable) accession number: G0HPP9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 25, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported