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G0HPP9

- G0HPP9_THES4

UniProt

G0HPP9 - G0HPP9_THES4

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Thermococcus sp. (strain CGMCC 1.5172 / 4557)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 15 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciTSP1042877:GHEX-2162-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    Ordered Locus Names:GQS_10630Imported
    OrganismiThermococcus sp. (strain CGMCC 1.5172 / 4557)Imported
    Taxonomic identifieri1042877 [NCBI]
    Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
    ProteomesiUP000000874: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.
    OMAiDEYMPDY.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G0HPP9-1 [UniParc]FASTAAdd to Basket

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    MIPRTMSTQH PDNVFIPFFA GSPTMGGEDE VIEAFYAFSV LGIDEQMWDF    50
    EGKEVDEFVV KKLFERYGYF FKRKKLGEEL RLTPRVPNPS VERAEAKLLL 100
    ETLEAIPRSA DYARLFYGEE LPPIFEVILP MTTSSQELNR VYELYRHYIA 150
    GKQYKRVHDI KLHEWIGEFY PSEIGVIPLF ESREAILSAA DIVREYLGGK 200
    EVEYQRVFLA RSDPAMNYGL ISAVLYDKLA LFELQGLEEE LGIPIYPIIG 250
    VGGAPFRGHF TPENVEGVLA EYPSVQTFTI QSSFKYDRTP KDVIRAVERI 300
    RESKRGKALP VPEEAFEILK KYEARYSEEL RALAPFIREV AKFVPSRRRR 350
    KLHIGLFGYS REVNGSALPR AIKFTASLYS LGIPPELLGL SALSEKELEF 400
    LGDYYLDLYR DIEFAFRYFN PKAAERFPFL KPLAKMARDY ERDERHGEIT 450
    SRILAGELSS ELIVEAAGIR GFLG 474
    Length:474
    Mass (Da):54,418
    Last modified:October 19, 2011 - v1
    Checksum:iEAE01A04E1D9ACE8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002920 Genomic DNA. Translation: AEK74019.1.
    RefSeqiWP_014013701.1. NC_015865.1.
    YP_004763696.1. NC_015865.1.

    Genome annotation databases

    EnsemblBacteriaiAEK74019; AEK74019; GQS_10630.
    GeneIDi11016810.
    KEGGithe:GQS_10630.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002920 Genomic DNA. Translation: AEK74019.1 .
    RefSeqi WP_014013701.1. NC_015865.1.
    YP_004763696.1. NC_015865.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEK74019 ; AEK74019 ; GQS_10630 .
    GeneIDi 11016810.
    KEGGi the:GQS_10630.

    Phylogenomic databases

    KOi K01595.
    OMAi DEYMPDY.

    Enzyme and pathway databases

    BioCyci TSP1042877:GHEX-2162-MONOMER.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Thermococcus sp. strain 4557, a hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent area."
      Wang X., Gao Z., Xu X., Ruan L.
      J. Bacteriol. 193:5544-5545(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CGMCC 1.5172 / 4557Imported.

    Entry informationi

    Entry nameiG0HPP9_THES4
    AccessioniPrimary (citable) accession number: G0HPP9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 15 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3