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G0HNE2 (G0HNE2_THES4) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Thymidine kinase HAMAP-Rule MF_00124

EC=2.7.1.21 HAMAP-Rule MF_00124
Gene names
Name:tdk HAMAP-Rule MF_00124
Ordered Locus Names:GQS_09495 EMBL AEK73793.1
OrganismThermococcus sp. (strain CGMCC 1.5172 / 4557) [Complete proteome] [HAMAP] EMBL AEK73793.1
Taxonomic identifier1042877 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding13 – 208ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding91 – 944ATP By similarity HAMAP-Rule MF_00124

Sites

Active site921Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1481Zinc By similarity HAMAP-Rule MF_00124
Metal binding1511Zinc By similarity HAMAP-Rule MF_00124
Metal binding1861Zinc By similarity HAMAP-Rule MF_00124
Metal binding1891Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
G0HNE2 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 649C7BB9C1F9AAE6

FASTA19321,520
        10         20         30         40         50         60 
MVHPGGFLEV ITGPMFAGKT TELIKRIERQ TFAKRKAALF KPSIDNRYSE DDVVAHNGLR 

        70         80         90        100        110        120 
YEAFVVPTNE EGVELIERIT LDEGFEVIGV DEVQFFPQVI VETLNRLADE GIYVIASGLN 

       130        140        150        160        170        180 
LDFKGDPFPV TRDLLVRADN IVYLTAVCTV CGKPATRSQR LIDGKPAPRD SPIILVGSSE 

       190 
SYEARCREHH FVP 

« Hide

References

[1]"Complete Genome Sequence of Thermococcus sp. Strain 4557, a Hyperthermophilic Archaeon Isolated from a Deep-Sea Hydrothermal Vent Area."
Wang X., Gao Z., Xu X., Ruan L.
J. Bacteriol. 193:5544-5545(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CGMCC 1.5172 / 4557.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002920 Genomic DNA. Translation: AEK73793.1.
RefSeqYP_004763470.1. NC_015865.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEK73793; AEK73793; GQS_09495.
GeneID11016581.
KEGGthe:GQS_09495.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00857.
OMADHISEST.

Enzyme and pathway databases

BioCycTSP1042877:GHEX-1933-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0HNE2_THES4
AccessionPrimary (citable) accession number: G0HNE2
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 11, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)