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G0HJT4 (G0HJT4_THES4) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 15. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nucleoside diphosphate kinase HAMAP-Rule MF_00451
Short name=NDK HAMAP-Rule MF_00451
Short name=NDP kinase HAMAP-Rule MF_00451
EC=2.7.4.6 HAMAP-Rule MF_00451
Alternative name(s):
Nucleoside-2-P kinase HAMAP-Rule MF_00451
Gene names
Name:ndk HAMAP-Rule MF_00451 EMBL AEK71946.1
Ordered Locus Names:GQS_00215
OrganismThermococcus sp. (strain CGMCC 1.5172 / 4557) [Complete proteome] [HAMAP] EMBL AEK71946.1
Taxonomic identifier1042877 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Thermococci › Thermococcales › Thermococcaceae › Thermococcus

Protein attributes

Sequence length174 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate By similarity. HAMAP-Rule MF_00451

Catalytic activity

ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. RuleBase RU004013 HAMAP-Rule MF_00451

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00451

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00451.

Sequence similarities

Belongs to the NDK family. HAMAP-Rule MF_00451 RuleBase RU004011

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site1231Pros-phosphohistidine intermediate By similarity HAMAP-Rule MF_00451
Binding site141ATP By similarity HAMAP-Rule MF_00451
Binding site621ATP By similarity HAMAP-Rule MF_00451
Binding site901ATP By similarity HAMAP-Rule MF_00451
Binding site961ATP By similarity HAMAP-Rule MF_00451
Binding site1071ATP By similarity HAMAP-Rule MF_00451

Sequences

Sequence LengthMass (Da)Tools
G0HJT4 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: A13564C4649237CC

FASTA17420,151
        10         20         30         40         50         60 
MVEKKIERTL VILKPDAVVR GLMGEIISRF EKRGLKIVGM KMIWIDREMA EKHYEEHKGK 

        70         80         90        100        110        120 
PFFEPLIDYI TKAPSVVMVV EGRYAISVVR KMSGATDPKD AEPGSIRGDY GLDIGDSIYN 

       130        140        150        160        170 
IIHASDSPES AEREINLYFK PDELYRYCKA ADWFYHTHAR AKREYLDTMD CLER

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References

[1]"Complete genome sequence of Thermococcus sp. strain 4557, a hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent area."
Wang X., Gao Z., Xu X., Ruan L.
J. Bacteriol. 193:5544-5545(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CGMCC 1.5172 / 4557.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002920 Genomic DNA. Translation: AEK71946.1.
RefSeqYP_004761623.1. NC_015865.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEK71946; AEK71946; GQS_00215.
GeneID11014691.
KEGGthe:GQS_00215.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00940.
OMAIARFERK.

Family and domain databases

Gene3D3.30.70.141. 1 hit.
HAMAPMF_00451. NDP_kinase.
InterProIPR001564. Nucleoside_diP_kinase.
IPR023005. Nucleoside_diP_kinase_AS.
[Graphical view]
PANTHERPTHR11349. PTHR11349. 1 hit.
PfamPF00334. NDK. 1 hit.
[Graphical view]
PRINTSPR01243. NUCDPKINASE.
SMARTSM00562. NDK. 1 hit.
[Graphical view]
SUPFAMSSF54919. NDK. 1 hit.
PROSITEPS00469. NDP_KINASES. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0HJT4_THES4
AccessionPrimary (citable) accession number: G0HJT4
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 3, 2013
This is version 15 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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