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Protein
Submitted name:

Malate dehydrogenase

Gene

GYY_03235

Organism
Methanococcus maripaludis X1
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei178Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Malate dehydrogenaseImported (EC:1.1.1.37Imported)
Gene namesi
ORF Names:GYY_03235Imported
OrganismiMethanococcus maripaludis X1Imported
Taxonomic identifieri1053692 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000008889 Componenti: Chromosome

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 145Ldh_1_NInterPro annotationAdd BLAST144
Domaini148 – 304Ldh_1_CInterPro annotationAdd BLAST157

Sequence similaritiesi

Belongs to the LDH/MDH superfamily.UniRule annotation

Phylogenomic databases

KOiK00024.
OMAiMDLMQTA.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProiIPR001557. L-lactate/malate_DH.
IPR018177. L-lactate_DH_AS.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11540. PTHR11540. 1 hit.
PfamiPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
PRINTSiPR00086. LLDHDRGNASE.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF56327. SSF56327. 1 hit.
PROSITEiPS00064. L_LDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0H495-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVSIIGASG KIGSVLSLLL AKESYIKNIN LIARSSSINK LKGLKMDLYD
60 70 80 90 100
AMAAAGQDTD IDICCDDDLS CTANSDITII TAGMARTGEM SRIDLMKGNA
110 120 130 140 150
KIVKNYVKNI ANFGDTKIFM ISNPVDLMTY KALIESGYEK NQVFGLGTHL
160 170 180 190 200
DSMRFKVAVA KHFEVHLDDV RTRIVGEHGD SMVPVISATA VGGIPIKRLP
210 220 230 240 250
KYEDFPYEKI LERIKGYGQE IINLKNGSEY GPASAIVNIV RCIAHDEKRL
260 270 280 290 300
LTLSTYIEDE IEGIEGGCCI GVPVKVGKNG IEEVIHIKME DDEIEGFKKS
310
FELVKGYCRQ IESI
Length:314
Mass (Da):34,494
Last modified:October 19, 2011 - v1
Checksum:i4C3E363B5AEB6784
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002913 Genomic DNA. Translation: AEK19526.1.
RefSeqiWP_013999015.1. NC_015847.1.

Genome annotation databases

GeneIDi10982073.
KEGGimmd:GYY_03235.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002913 Genomic DNA. Translation: AEK19526.1.
RefSeqiWP_013999015.1. NC_015847.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10982073.
KEGGimmd:GYY_03235.

Phylogenomic databases

KOiK00024.
OMAiMDLMQTA.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
3.90.110.10. 1 hit.
InterProiIPR001557. L-lactate/malate_DH.
IPR018177. L-lactate_DH_AS.
IPR022383. Lactate/malate_DH_C.
IPR001236. Lactate/malate_DH_N.
IPR015955. Lactate_DH/Glyco_Ohase_4_C.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR11540. PTHR11540. 1 hit.
PfamiPF02866. Ldh_1_C. 1 hit.
PF00056. Ldh_1_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000102. Lac_mal_DH. 1 hit.
PRINTSiPR00086. LLDHDRGNASE.
SUPFAMiSSF51735. SSF51735. 1 hit.
SSF56327. SSF56327. 1 hit.
PROSITEiPS00064. L_LDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiG0H495_METMI
AccessioniPrimary (citable) accession number: G0H495
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 2, 2016
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.