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G0H2Y6 (G0H2Y6_METMI) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP-Rule MF_01201

EC=5.1.1.1 HAMAP-Rule MF_01201
Gene names
ORF Names:GYY_08400 EMBL AEK20533.1
OrganismMethanococcus maripaludis X1 [Complete proteome] EMBL AEK20533.1
Taxonomic identifier1053692 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus

Protein attributes

Sequence length373 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP-Rule MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP-Rule MF_01201

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201

Ontologies

Keywords
   LigandPyridoxal phosphate HAMAP-Rule MF_01201
   Molecular functionIsomerase HAMAP-Rule MF_01201
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-alanine biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionalanine racemase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

pyridoxal phosphate binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site371Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2661Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1351Substrate By similarity HAMAP-Rule MF_01201
Binding site3131Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue371N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
G0H2Y6 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 5972051191F3ECAF

FASTA37341,460
        10         20         30         40         50         60 
MVSHPIWAEI DLSAIKNNIK EIRRITNPKS QVMAVVKANA YGHGSVEVSK VCLENGADRL 

        70         80         90        100        110        120 
AVARSTEALE LRNAGITCPI LVFGYVTEEE ILKMVENDIT LTVYSLEIAN SIQKIAEKLG 

       130        140        150        160        170        180 
KHSKIHIKVD TGMSRLGFLP EKSSVETIKK IRELKNIEVE GIYTHFADAD NSDKTYTTMQ 

       190        200        210        220        230        240 
FSKFTSFLHD LEENGINIPI KHASNSAAII DHPETHLNMV RPGIILYGLY PSELVHKERI 

       250        260        270        280        290        300 
NLQPAMSLKV LVTHVKDVPE NTKISYGCTF ETKKQSKIAS LPIGYADGFT RMLKNGNVLI 

       310        320        330        340        350        360 
HGLRVPVVGR ICMDQCMIDV SGIENVNVGD VVTVFGKDGN EKISIEEFGN KLGTINYELV 

       370 
CMVSARVPRI YLH 

« Hide

References

[1]"Complete Genome Sequence of a Nonculturable Methanococcus maripaludis Strain Extracted in a Metagenomic Survey of Petroleum Reservoir Fluids."
Wang X., Greenfield P., Li D., Hendry P., Volk H., Sutherland T.D.
J. Bacteriol. 193:5595-5595(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: X1 EMBL AEK20533.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002913 Genomic DNA. Translation: AEK20533.1.
RefSeqYP_004743276.1. NC_015847.1.

3D structure databases

ProteinModelPortalG0H2Y6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10983088.
KEGGmmd:GYY_08400.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01775.
OMAAEININN.

Enzyme and pathway databases

BioCycMMAR1053692:GH1C-1673-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0H2Y6_METMI
AccessionPrimary (citable) accession number: G0H2Y6
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: July 9, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)