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G0H2V1 (G0H2V1_METMI) Unreviewed, UniProtKB/TrEMBL

Last modified March 6, 2013. Version 10. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable cobyrinic acid A,C-diamide synthase HAMAP-Rule MF_00027
Gene names
Name:cobB HAMAP-Rule MF_00027
ORF Names:GYY_08225 EMBL AEK20498.1
OrganismMethanococcus maripaludis (Methanococcus deltae)
Taxonomic identifier39152 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanococci › Methanococcales › Methanococcaceae › Methanococcus

Protein attributes

Sequence length447 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH2 groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation By similarity. HAMAP-Rule MF_00027

Pathway

Cofactor biosynthesis; adenosylcobalamin biosynthesis. HAMAP-Rule MF_00027

Sequence similarities

Belongs to the CobB/CobQ family. CobB subfamily. HAMAP-Rule MF_00027

Contains 1 GATase cobBQ-type domain. HAMAP-Rule MF_00027

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain252 – 439188GATase cobBQ-type By similarity HAMAP-Rule MF_00027

Sites

Active site3311Nucleophile By similarity HAMAP-Rule MF_00027
Active site4311 By similarity HAMAP-Rule MF_00027

Sequences

Sequence LengthMass (Da)Tools
G0H2V1 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 9E792400D21CBE2C

FASTA44750,092
        10         20         30         40         50         60 
MKRIVIAGTS SMVGKTTIST GIMKALSKKH DVQPYKIGPD YIDPTYHTEA TKNKSRNLDS 

        70         80         90        100        110        120 
FFMDEMQVRS IFKRHSKNKD ISVIEGVRGL YEGISPYNDV GSTASVAKAI NSPVILLMDA 

       130        140        150        160        170        180 
RSLTRSAAAI IKGFKSFDPD LNIKGVIFNK IRGEGHLNKL KEAVKYYDNE IEIIGAIPRD 

       190        200        210        220        230        240 
DSLSVSQRHL GLVPTPENKQ ELLERIDLWG ETVEGCLDLE KIVELSDESF DFCVDEKNKE 

       250        260        270        280        290        300 
ETLWKVEKNN SKIAVALDES FNFYYWDNFD ALEENGAKLK FFSPLNDSEV PDCDTIYLGG 

       310        320        330        340        350        360 
GYPEIFPEKL SNNKSMIESI RNFDGKIYGE CGGLMYLTNS IDGREMLKLI DADAVMTPNV 

       370        380        390        400        410        420 
QGLSYVKGTF EKDCIIGKKS KEFKAHEFHY SKLININEKD FSYKINRGKG IINSMDGITS 

       430        440 
KDGDIVGGYA HQHCIGNPHF AASLSKM

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References

[1]"Complete Genome Sequence of a Nonculturable Methanococcus maripaludis Strain Extracted in a Metagenomic Survey of Petroleum Reservoir Fluids."
Wang X., Greenfield P., Li D., Hendry P., Volk H., Sutherland T.D.
J. Bacteriol. 193:5595-5595(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: X1 EMBL AEK20498.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002913 Genomic DNA. Translation: AEK20498.1.
RefSeqYP_004743241.1. NC_015847.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID10983053.
KEGGmmd:GYY_08225.

Phylogenomic databases

KOK02224.
OMACWLPGGY.

Enzyme and pathway databases

BioCycMMAR1053692:GH1C-1636-MONOMER.
UniPathwayUPA00148.

Family and domain databases

HAMAPMF_00027. CobB.
InterProIPR004484. CbiA_synth.
IPR017929. CobB/CobQ_GATase.
IPR002586. CobQ/CobB/MinD/ParA_Nub-bd_dom.
IPR011698. GATase_3.
[Graphical view]
PfamPF01656. CbiA. 1 hit.
PF07685. GATase_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00379. cobB. 1 hit.
PROSITEPS51274. GATASE_COBBQ. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0H2V1_METMI
AccessionPrimary (citable) accession number: G0H2V1
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: March 6, 2013
This is version 10 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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