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G0GW23

- G0GW23_RICH0

UniProt

G0GW23 - G0GW23_RICH0

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Protein
Tyrosine recombinase XerC
Gene
xerC, Rh054_06895
Organism
Rickettsia heilongjiangensis (strain ATCC VR-1524 / 054)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei159 – 1591 By similarityUniRule annotation
Active sitei182 – 1821 By similarityUniRule annotation
Active sitei250 – 2501 By similarityUniRule annotation
Active sitei253 – 2531 By similarityUniRule annotation
Active sitei276 – 2761 By similarityUniRule annotation
Active sitei285 – 2851O-(3'-phospho-DNA)-tyrosine intermediate By similarityUniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. chromosome segregation Source: UniProtKB-HAMAP
  4. transposition, DNA-mediated Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotation, Chromosome partitionUniRule annotation, DNA integrationUniRule annotationSAAS annotations, DNA recombinationUniRule annotationSAAS annotations

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciRHEI1032845:GI4V-1231-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine recombinase XerCUniRule annotation
Gene namesi
Name:xerCUniRule annotationImported
Ordered Locus Names:Rh054_06895Imported
OrganismiRickettsia heilongjiangensis (strain ATCC VR-1524 / 054)Imported
Taxonomic identifieri1032845 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
ProteomesiUP000000865: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotationSAAS annotations

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotations

Interactioni

Subunit structurei

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK03733.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF56349. SSF56349. 1 hit.

Sequencei

Sequence statusi: Complete.

G0GW23-1 [UniParc]FASTAAdd to Basket

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MLDTSIQALI NKWQKYLVLQ RNYSNHTAIS YNNDLKHFLE FMNYYNSELV    50
TINHIKTADI RLIRSWLAKR NCDNFTASSI SRGLSAVKNF YRFLEKTTQL 100
NSHIIFSIKS PKKTKLLPKA LSEDDVVISL EHIEEYGNVK WVELRNKALL 150
VLIYASGLRI SEALSITKLH LQNLEFIRII GKGSKERIIP WLPIAKNLIT 200
QYLEILPYKL GDNEPIFRGK QGKKLQPPVF NRELIKLKHF YGLPQHLTAH 250
SFRHSFASHL LEHGADLRSL QELLGHKSLS TTQNYTKTSI KHLEAVYTTA 300
YPIKK 305
Length:305
Mass (Da):35,353
Last modified:October 19, 2011 - v1
Checksum:i945F4F61D5880823
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002912 Genomic DNA. Translation: AEK75228.1.
RefSeqiYP_004764906.1. NC_015866.1.

Genome annotation databases

EnsemblBacteriaiAEK75228; AEK75228; Rh054_06895.
GeneIDi11014539.
KEGGirhe:Rh054_06895.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002912 Genomic DNA. Translation: AEK75228.1 .
RefSeqi YP_004764906.1. NC_015866.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEK75228 ; AEK75228 ; Rh054_06895 .
GeneIDi 11014539.
KEGGi rhe:Rh054_06895.

Phylogenomic databases

KOi K03733.

Enzyme and pathway databases

BioCyci RHEI1032845:GI4V-1231-MONOMER.

Family and domain databases

Gene3Di 1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPi MF_01808. Recomb_XerC.
InterProi IPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view ]
Pfami PF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view ]
SUPFAMi SSF56349. SSF56349. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete Genome Sequence of Rickettsia heilongjiangensis, an Emerging Tick-Transmitted Human Pathogen."
    Duan C., Tong Y., Huang Y., Wang X., Xiong X., Wen B.
    J. Bacteriol. 193:5564-5565(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC VR-1524 / 054.

Entry informationi

Entry nameiG0GW23_RICH0
AccessioniPrimary (citable) accession number: G0GW23
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 11, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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