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G0GW23

- G0GW23_RICH0

UniProt

G0GW23 - G0GW23_RICH0

Protein

Tyrosine recombinase XerC

Gene

xerC

Organism
Rickettsia heilongjiangensis (strain ATCC VR-1524 / 054)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei159 – 1591UniRule annotation
    Active sitei182 – 1821UniRule annotation
    Active sitei250 – 2501UniRule annotation
    Active sitei253 – 2531UniRule annotation
    Active sitei276 – 2761UniRule annotation
    Active sitei285 – 2851O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. cell cycle Source: UniProtKB-KW
    2. cell division Source: UniProtKB-KW
    3. chromosome segregation Source: UniProtKB-HAMAP
    4. transposition, DNA-mediated Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Cell cycle, Cell divisionUniRule annotation, Chromosome partitionUniRule annotation, DNA integrationUniRule annotationSAAS annotation, DNA recombinationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciRHEI1032845:GI4V-1231-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tyrosine recombinase XerCUniRule annotation
    Gene namesi
    Name:xerCUniRule annotationImported
    Ordered Locus Names:Rh054_06895Imported
    OrganismiRickettsia heilongjiangensis (strain ATCC VR-1524 / 054)Imported
    Taxonomic identifieri1032845 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeRickettsiaspotted fever group
    ProteomesiUP000000865: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the 'phage' integrase family. XerC subfamily.UniRule annotation

    Phylogenomic databases

    KOiK03733.

    Family and domain databases

    Gene3Di1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPiMF_01808. Recomb_XerC.
    InterProiIPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view]
    PfamiPF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56349. SSF56349. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G0GW23-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLDTSIQALI NKWQKYLVLQ RNYSNHTAIS YNNDLKHFLE FMNYYNSELV    50
    TINHIKTADI RLIRSWLAKR NCDNFTASSI SRGLSAVKNF YRFLEKTTQL 100
    NSHIIFSIKS PKKTKLLPKA LSEDDVVISL EHIEEYGNVK WVELRNKALL 150
    VLIYASGLRI SEALSITKLH LQNLEFIRII GKGSKERIIP WLPIAKNLIT 200
    QYLEILPYKL GDNEPIFRGK QGKKLQPPVF NRELIKLKHF YGLPQHLTAH 250
    SFRHSFASHL LEHGADLRSL QELLGHKSLS TTQNYTKTSI KHLEAVYTTA 300
    YPIKK 305
    Length:305
    Mass (Da):35,353
    Last modified:October 19, 2011 - v1
    Checksum:i945F4F61D5880823
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002912 Genomic DNA. Translation: AEK75228.1.
    RefSeqiYP_004764906.1. NC_015866.1.

    Genome annotation databases

    EnsemblBacteriaiAEK75228; AEK75228; Rh054_06895.
    GeneIDi11014539.
    KEGGirhe:Rh054_06895.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002912 Genomic DNA. Translation: AEK75228.1 .
    RefSeqi YP_004764906.1. NC_015866.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEK75228 ; AEK75228 ; Rh054_06895 .
    GeneIDi 11014539.
    KEGGi rhe:Rh054_06895.

    Phylogenomic databases

    KOi K03733.

    Enzyme and pathway databases

    BioCyci RHEI1032845:GI4V-1231-MONOMER.

    Family and domain databases

    Gene3Di 1.10.150.130. 1 hit.
    1.10.443.10. 1 hit.
    HAMAPi MF_01808. Recomb_XerC.
    InterProi IPR011010. DNA_brk_join_enz.
    IPR013762. Integrase-like_cat-core.
    IPR002104. Integrase_catalytic.
    IPR023109. Integrase_recombinase_N.
    IPR004107. Integrase_SAM-like_N.
    IPR023009. Tyrosine_recombinase_XerC/XerD.
    [Graphical view ]
    Pfami PF02899. Phage_int_SAM_1. 1 hit.
    PF00589. Phage_integrase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56349. SSF56349. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of Rickettsia heilongjiangensis, an emerging tick-transmitted human pathogen."
      Duan C., Tong Y., Huang Y., Wang X., Xiong X., Wen B.
      J. Bacteriol. 193:5564-5565(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC VR-1524 / 054Imported.

    Entry informationi

    Entry nameiG0GW23_RICH0
    AccessioniPrimary (citable) accession number: G0GW23
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3