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G0GRW1

- G0GRW1_KLEPN

UniProt

G0GRW1 - G0GRW1_KLEPN

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Klebsiella pneumoniae KCTC 2242
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 12 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei138 – 1381UniRule annotation
    Active sitei546 – 5461UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciKPNE1049565:GLF0-4887-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    ORF Names:KPN2242_24270Imported
    OrganismiKlebsiella pneumoniae KCTC 2242Imported
    Taxonomic identifieri1049565 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeKlebsiella
    ProteomesiUP000008890: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    KOiK01595.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G0GRW1-1 [UniParc]FASTAAdd to Basket

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    MNEQYSALRS NVSMLGKVLG DTIKDALGEN ILDRVETIRK LSKSSRAGNE    50
    ANRQELLTTL QNLSNDELLP VARAFSQFLN LANTAEQYHS ISANGEAASN 100
    PEVIARTLRK LKDQPNLNEE TIKQAVESLS LELVLTAHPT EITRRTLIHK 150
    MVEVNNCLKQ LDNKDIADYE HHQLMRRLRQ LIAQSWHTDE IRKHRPSPVD 200
    EAKWGFAVVE NSLWEGVPNY LRELNEQLEA NLGYQLPVDF VPVRFTSWMG 250
    GDRDGNPNVT ADITRHVLLL SRWKATDLFL KDVQVLISEL SMVECTDELR 300
    ALAGAEGAQE PYRYLMKKLR SQLMETQAWL EARLKGQKLP KPAGLITQNE 350
    QLWEPLYACY KSLQACGMGI IANGELLDTL RRVKSFGVPL VRIDIRQEST 400
    RHTEALGEMT RYLGIGDYES WSEADKQAFL IRELNSKRPL LPRQWEPSEE 450
    TREVLDTCKV IAEAPRGSIA AYVISMAKTP SDVLAVHLLL KEAGIGFALP 500
    VAPLFETLDD LNNANDVMTQ LLNIDWYRGF IQGKQMVMIG YSDSAKDAGV 550
    MAASWAQYQA QDALIKTCEK AGIELTLFHG RGGSIGRGGA PAHAALLSQP 600
    PGSLKGGLRV TEQGEMIRFK YGLPEVTISS LSLYTSAILE ANLLPPPEPK 650
    AEWRDIMAEL SDVSCKMYRG YVRENKDFVP YFRSATPEQE LGKLPLGSRP 700
    AKRRPTGGVE SLRAIPWIFA WTQNRLMLPA WLGAGAALQK VVEGGKQSEL 750
    EAMCRDWPFF STRLGMLEMV YSKADLWLAE YYDQRLVKPE LWALGSELRK 800
    LLAADINVVL AIANDSHLMA DLPWIAESIQ LRNIYTDPLN VLQAELLHRS 850
    RQAEEEGKDP DPRVEQALMV TIAGVAAGMR NTG 883
    Length:883
    Mass (Da):98,946
    Last modified:October 19, 2011 - v1
    Checksum:i7E3810AF3B98025F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002910 Genomic DNA. Translation: AEK00726.1.
    RefSeqiYP_005957290.1. NC_017540.1.

    Genome annotation databases

    EnsemblBacteriaiAEK00726; AEK00726; KPN2242_24270.
    GeneIDi12548234.
    KEGGikpo:KPN2242_24270.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002910 Genomic DNA. Translation: AEK00726.1 .
    RefSeqi YP_005957290.1. NC_017540.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEK00726 ; AEK00726 ; KPN2242_24270 .
    GeneIDi 12548234.
    KEGGi kpo:KPN2242_24270.

    Phylogenomic databases

    KOi K01595.

    Enzyme and pathway databases

    BioCyci KPNE1049565:GLF0-4887-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00781. PEPCASE_1. 1 hit.
    PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete Genome Sequence of the 2,3-Butanediol-Producing Klebsiella pneumoniae Strain KCTC 2242."
      Shin S.H., Kim S., Kim J.Y., Lee S., Um Y., Oh M.K., Kim Y.R., Lee J., Yang K.S.
      J. Bacteriol. 194:2736-2737(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: KCTC 2242Imported.

    Entry informationi

    Entry nameiG0GRW1_KLEPN
    AccessioniPrimary (citable) accession number: G0GRW1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 12 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3