Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

G0GD69 (G0GD69_SPITZ) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Spith_1886 EMBL AEJ62144.1
OrganismSpirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203) [Complete proteome] [HAMAP] EMBL AEJ62144.1
Taxonomic identifier869211 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeSpirochaeta

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity.

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
G0GD69 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: DADB099D03432422

FASTA40244,319
        10         20         30         40         50         60 
MGEKIRKEAG GLVVPDEPVI PFIQGDGTGP DIWRAAVRVF DAAVEKAYGG RRKVAWLEVF 

        70         80         90        100        110        120 
AGERAYREKG TWLPDETLEA FKEYLVGIKG PLTTPVGGGF RSLNVTLRQM LDLYVCLRPV 

       130        140        150        160        170        180 
KYYPGIPSPV RHPELVDMVV FRENTEDVYA GFELPSGDER TKRLIEFCRR EFGWQIREDS 

       190        200        210        220        230        240 
GIGVKPISPT GTKRLVRAAI RYALDHGRRS VTLVHKGNIM KYTEGAFRAW GYEVAKEEFG 

       250        260        270        280        290        300 
DRVVTWEDVP DGVVPEGKVL VKDAIADAFL QQILTRPAEF DVIATMNLNG DYVSDALAAQ 

       310        320        330        340        350        360 
VGGIGIAPGA NINYDTGHAI FEATHGTAPK YAGKDMVNPS SVILSGKMMF EYLGWHEAAA 

       370        380        390        400 
LIEKGLTGAI ASRKVTYDFA RLMEGAEQVS TSEFGNQIVA HM 

« Hide

References

[1]"The complete genome of Spirochaeta thermophila DSM 6578."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Lapidus A., Bruce D., Goodwin L., Pitluck S., Peters L., Kyrpides N., Mavromatis K., Ivanova N., Mikailova N., Pagani I., Chertkov O., Detter J.C., Tapia R., Han C., Land M., Hauser L., Markowitz V. expand/collapse author list , Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Spring S., Merkhoffer B., Schneider S., Klenk H.-P., Eisen J.A.
Submitted (JUN-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700085 / DSM 6578 / Z-1203.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002903 Genomic DNA. Translation: AEJ62144.1.
RefSeqYP_006045861.1. NC_017583.1.

3D structure databases

ProteinModelPortalG0GD69.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEJ62144; AEJ62144; Spith_1886.
GeneID12640651.
KEGGstq:Spith_1886.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycSTHE869211:GLKE-1927-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0GD69_SPITZ
AccessionPrimary (citable) accession number: G0GD69
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: October 16, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)