SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

G0GD69

- G0GD69_SPITZ

UniProt

G0GD69 - G0GD69_SPITZ

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Isocitrate dehydrogenase [NADP]
Gene
Spith_1886
Organism
Spirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.

Cofactori

Binds 1 magnesium or manganese ion per subunit By similarity.

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  3. magnesium ion binding Source: InterPro

GO - Biological processi

  1. glyoxylate cycle Source: UniProtKB-KW
  2. tricarboxylic acid cycle Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

Enzyme and pathway databases

BioCyciSTHE869211:GLKE-1927-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
Gene namesi
Ordered Locus Names:Spith_1886Imported
OrganismiSpirochaeta thermophila (strain ATCC 700085 / DSM 6578 / Z-1203)Imported
Taxonomic identifieri869211 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesSpirochaetaceaeSpirochaeta
ProteomesiUP000007254: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG0GD69.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0GD69-1 [UniParc]FASTAAdd to Basket

« Hide

MGEKIRKEAG GLVVPDEPVI PFIQGDGTGP DIWRAAVRVF DAAVEKAYGG    50
RRKVAWLEVF AGERAYREKG TWLPDETLEA FKEYLVGIKG PLTTPVGGGF 100
RSLNVTLRQM LDLYVCLRPV KYYPGIPSPV RHPELVDMVV FRENTEDVYA 150
GFELPSGDER TKRLIEFCRR EFGWQIREDS GIGVKPISPT GTKRLVRAAI 200
RYALDHGRRS VTLVHKGNIM KYTEGAFRAW GYEVAKEEFG DRVVTWEDVP 250
DGVVPEGKVL VKDAIADAFL QQILTRPAEF DVIATMNLNG DYVSDALAAQ 300
VGGIGIAPGA NINYDTGHAI FEATHGTAPK YAGKDMVNPS SVILSGKMMF 350
EYLGWHEAAA LIEKGLTGAI ASRKVTYDFA RLMEGAEQVS TSEFGNQIVA 400
HM 402
Length:402
Mass (Da):44,319
Last modified:October 19, 2011 - v1
Checksum:iDADB099D03432422
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002903 Genomic DNA. Translation: AEJ62144.1.
RefSeqiWP_014625469.1. NC_017583.1.
YP_006045861.1. NC_017583.1.

Genome annotation databases

EnsemblBacteriaiAEJ62144; AEJ62144; Spith_1886.
GeneIDi12640651.
KEGGistq:Spith_1886.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002903 Genomic DNA. Translation: AEJ62144.1 .
RefSeqi WP_014625469.1. NC_017583.1.
YP_006045861.1. NC_017583.1.

3D structure databases

ProteinModelPortali G0GD69.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEJ62144 ; AEJ62144 ; Spith_1886 .
GeneIDi 12640651.
KEGGi stq:Spith_1886.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci STHE869211:GLKE-1927-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 1 hit.
InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
PANTHERi PTHR11835. PTHR11835. 1 hit.
Pfami PF00180. Iso_dh. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
PROSITEi PS00470. IDH_IMDH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700085 / DSM 6578 / Z-1203.

Entry informationi

Entry nameiG0GD69_SPITZ
AccessioniPrimary (citable) accession number: G0GD69
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: September 3, 2014
This is version 14 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

Similar proteinsi