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Protein

Elongation factor Tu

Gene

tuf

Organism
Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi82 – 86GTPUniRule annotation5
Nucleotide bindingi137 – 140GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factorUniRule annotationImported, HydrolaseImported
Biological processProtein biosynthesis
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufUniRule annotation
Ordered Locus Names:RAM_21475Imported
OrganismiAmycolatopsis mediterranei (strain S699) (Nocardia mediterranei)Imported
Taxonomic identifieri713604 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeAmycolatopsis
Proteomesi
  • UP000006138 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG0FQE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206Tr-type GInterPro annotationAdd BLAST197

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.
OMAiLDGIMPQ.
OrthoDBiPOG091H00LA.

Family and domain databases

CDDicd03697. EFTU_II. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B. 1 hit.
InterProiView protein in InterPro
IPR004161. EFTu-like_2.
IPR033720. EFTU_2.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
PfamiView protein in Pfam
PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51722. G_TR_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G0FQE2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKQQYVRTK PHLNIGTMGH VDHGKTTLTA AITKVLAEQG GTNRYVAFDR
60 70 80 90 100
IDRAPEEVER GITINIAHVE YETPTRHYAH VDMPGHADYV KNMITGAAQL
110 120 130 140 150
DGAVLVVSAQ DGAMPQTREH VVLARRIGVG HLVVALNKAD LADDEELLDL
160 170 180 190 200
VELEVRELLT RYGFDGDAVP VVRVSGLRAL EGDPRWTQRI LDLLAAVDEH
210 220 230 240 250
VPIPPRRLDL PFLMPIENVL TITGRGTVVT GAVEQGTLTV GDAVEVIGLG
260 270 280 290 300
PAVTSVATGL ETFGKPMDRA EAGDNAAVLL RGVKRGEVRR GQVVCLPGSV
310 320 330 340 350
RPHRRFRADV HVLSAAEGGR RTPFAANYRP QFHFRTSDVV GVVTLADGVT
360 370 380 390
AVRPGDVASL TVELGQPVAM SPGLGFAMRE GRLTVAAGTV REVLD
Length:395
Mass (Da):42,507
Last modified:October 19, 2011 - v1
Checksum:iE35CB3BAFE01E9B3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002896 Genomic DNA. Translation: AEK42775.1.
RefSeqiWP_013226063.1. NC_018266.1.

Genome annotation databases

EnsemblBacteriaiAEK42775; AEK42775; RAM_21475.
KEGGiamm:AMES_4166.
amn:RAM_21475.
PATRICifig|713604.12.peg.4435.

Similar proteinsi

Entry informationi

Entry nameiG0FQE2_AMYMS
AccessioniPrimary (citable) accession number: G0FQE2
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: September 27, 2017
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported