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G0FQE2

- G0FQE2_AMYMS

UniProt

G0FQE2 - G0FQE2_AMYMS

Protein

Elongation factor Tu

Gene

tufA

Organism
Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi82 – 865GTPUniRule annotation
    Nucleotide bindingi137 – 1404GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported, HydrolaseImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufAImported
    Synonyms:tufUniRule annotation
    Ordered Locus Names:AMES_4166Imported, RAM_21475Imported
    OrganismiAmycolatopsis mediterranei (strain S699) (Nocardia mediterranei)Imported
    Taxonomic identifieri713604 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeAmycolatopsis
    ProteomesiUP000006138: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.UniRule annotation
    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    KOiK02358.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G0FQE2-1 [UniParc]FASTAAdd to Basket

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    MTKQQYVRTK PHLNIGTMGH VDHGKTTLTA AITKVLAEQG GTNRYVAFDR    50
    IDRAPEEVER GITINIAHVE YETPTRHYAH VDMPGHADYV KNMITGAAQL 100
    DGAVLVVSAQ DGAMPQTREH VVLARRIGVG HLVVALNKAD LADDEELLDL 150
    VELEVRELLT RYGFDGDAVP VVRVSGLRAL EGDPRWTQRI LDLLAAVDEH 200
    VPIPPRRLDL PFLMPIENVL TITGRGTVVT GAVEQGTLTV GDAVEVIGLG 250
    PAVTSVATGL ETFGKPMDRA EAGDNAAVLL RGVKRGEVRR GQVVCLPGSV 300
    RPHRRFRADV HVLSAAEGGR RTPFAANYRP QFHFRTSDVV GVVTLADGVT 350
    AVRPGDVASL TVELGQPVAM SPGLGFAMRE GRLTVAAGTV REVLD 395
    Length:395
    Mass (Da):42,507
    Last modified:October 19, 2011 - v1
    Checksum:iE35CB3BAFE01E9B3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002896 Genomic DNA. Translation: AEK42775.1.
    CP003729 Genomic DNA. Translation: AFO77702.1.
    RefSeqiYP_005532232.1. NC_017186.1.
    YP_006550647.1. NC_018266.1.

    Genome annotation databases

    EnsemblBacteriaiAEK42775; AEK42775; RAM_21475.
    AFO77702; AFO77702; AMES_4166.
    GeneIDi12124868.
    13415170.
    KEGGiamm:AMES_4166.
    amn:RAM_21475.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002896 Genomic DNA. Translation: AEK42775.1 .
    CP003729 Genomic DNA. Translation: AFO77702.1 .
    RefSeqi YP_005532232.1. NC_017186.1.
    YP_006550647.1. NC_018266.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEK42775 ; AEK42775 ; RAM_21475 .
    AFO77702 ; AFO77702 ; AMES_4166 .
    GeneIDi 12124868.
    13415170.
    KEGGi amm:AMES_4166.
    amn:RAM_21475.

    Phylogenomic databases

    KOi K02358.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699."
      Verma M., Kaur J., Kumar M., Kumari K., Saxena A., Anand S., Nigam A., Ravi V., Raghuvanshi S., Khurana P., Tyagi A.K., Khurana J.P., Lal R.
      J. Bacteriol. 193:5562-5563(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S699Imported.
    2. "Complete genome sequence of Amycolatopsis mediterranei S699 based on de novo assembly via a combinatorial sequencing strategy."
      Tang B., Zhao W., Zheng H., Zhuo Y., Zhang L., Zhao G.P.
      J. Bacteriol. 194:5699-5700(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S699Imported.
    3. Biao T.
      Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: S699Imported.

    Entry informationi

    Entry nameiG0FQE2_AMYMS
    AccessioniPrimary (citable) accession number: G0FQE2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3