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G0FQE2

- G0FQE2_AMYMS

UniProt

G0FQE2 - G0FQE2_AMYMS

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Protein

Elongation factor Tu

Gene

tufA

Organism
Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi82 – 865GTPUniRule annotation
Nucleotide bindingi137 – 1404GTPUniRule annotation

GO - Molecular functioni

  1. GTPase activity Source: InterPro
  2. GTP binding Source: UniProtKB-HAMAP
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Elongation factorUniRule annotation, HydrolaseImported

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tufAImported
Synonyms:tufUniRule annotation
Ordered Locus Names:AMES_4166Imported, RAM_21475Imported
OrganismiAmycolatopsis mediterranei (strain S699) (Nocardia mediterranei)Imported
Taxonomic identifieri713604 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeAmycolatopsis
ProteomesiUP000006138: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG0FQE2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

KOiK02358.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.

Sequencei

Sequence statusi: Complete.

G0FQE2 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKQQYVRTK PHLNIGTMGH VDHGKTTLTA AITKVLAEQG GTNRYVAFDR
60 70 80 90 100
IDRAPEEVER GITINIAHVE YETPTRHYAH VDMPGHADYV KNMITGAAQL
110 120 130 140 150
DGAVLVVSAQ DGAMPQTREH VVLARRIGVG HLVVALNKAD LADDEELLDL
160 170 180 190 200
VELEVRELLT RYGFDGDAVP VVRVSGLRAL EGDPRWTQRI LDLLAAVDEH
210 220 230 240 250
VPIPPRRLDL PFLMPIENVL TITGRGTVVT GAVEQGTLTV GDAVEVIGLG
260 270 280 290 300
PAVTSVATGL ETFGKPMDRA EAGDNAAVLL RGVKRGEVRR GQVVCLPGSV
310 320 330 340 350
RPHRRFRADV HVLSAAEGGR RTPFAANYRP QFHFRTSDVV GVVTLADGVT
360 370 380 390
AVRPGDVASL TVELGQPVAM SPGLGFAMRE GRLTVAAGTV REVLD
Length:395
Mass (Da):42,507
Last modified:October 19, 2011 - v1
Checksum:iE35CB3BAFE01E9B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002896 Genomic DNA. Translation: AEK42775.1.
CP003729 Genomic DNA. Translation: AFO77702.1.
RefSeqiYP_005532232.1. NC_017186.1.
YP_006550647.1. NC_018266.1.

Genome annotation databases

EnsemblBacteriaiAEK42775; AEK42775; RAM_21475.
AFO77702; AFO77702; AMES_4166.
GeneIDi12124868.
13415170.
KEGGiamm:AMES_4166.
amn:RAM_21475.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002896 Genomic DNA. Translation: AEK42775.1 .
CP003729 Genomic DNA. Translation: AFO77702.1 .
RefSeqi YP_005532232.1. NC_017186.1.
YP_006550647.1. NC_018266.1.

3D structure databases

ProteinModelPortali G0FQE2.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEK42775 ; AEK42775 ; RAM_21475 .
AFO77702 ; AFO77702 ; AMES_4166 .
GeneIDi 12124868.
13415170.
KEGGi amm:AMES_4166.
amn:RAM_21475.

Phylogenomic databases

KOi K02358.

Family and domain databases

Gene3Di 3.40.50.300. 1 hit.
HAMAPi MF_00118_B. EF_Tu_B.
InterProi IPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view ]
Pfami PF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view ]
PRINTSi PR00315. ELONGATNFCT.
SUPFAMi SSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699."
    Verma M., Kaur J., Kumar M., Kumari K., Saxena A., Anand S., Nigam A., Ravi V., Raghuvanshi S., Khurana P., Tyagi A.K., Khurana J.P., Lal R.
    J. Bacteriol. 193:5562-5563(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S699Imported.
  2. "Complete genome sequence of Amycolatopsis mediterranei S699 based on de novo assembly via a combinatorial sequencing strategy."
    Tang B., Zhao W., Zheng H., Zhuo Y., Zhang L., Zhao G.P.
    J. Bacteriol. 194:5699-5700(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S699Imported.
  3. Biao T.
    Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: S699Imported.

Entry informationi

Entry nameiG0FQE2_AMYMS
AccessioniPrimary (citable) accession number: G0FQE2
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: October 29, 2014
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3