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G0FNS9

- G0FNS9_AMYMS

UniProt

G0FNS9 - G0FNS9_AMYMS

Protein

DNA ligase

Gene

ligB

Organism
Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 21 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. DNA binding Source: InterPro
    3. DNA ligase (ATP) activity Source: UniProtKB-EC

    GO - Biological processi

    1. DNA ligation involved in DNA repair Source: InterPro
    2. DNA recombination Source: UniProtKB-KW
    3. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    LigaseUniRule annotationImported

    Keywords - Biological processi

    DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
    Gene namesi
    Name:ligBImported
    Synonyms:ligImported
    Ordered Locus Names:AMES_7943Imported, RAM_41435Imported
    OrganismiAmycolatopsis mediterranei (strain S699) (Nocardia mediterranei)Imported
    Taxonomic identifieri713604 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeAmycolatopsis
    ProteomesiUP000006138: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ATP-dependent DNA ligase family.UniRule annotation

    Phylogenomic databases

    KOiK01971.

    Family and domain databases

    Gene3Di1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProiIPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view]
    PfamiPF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsiTIGR00574. dnl1. 1 hit.
    PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G0FNS9-1 [UniParc]FASTAAdd to Basket

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    MLLSELVRAS AELAATRSRK AKIALLAELL RAAEIAELPT VIAYLTGQTA    50
    QDRLGAGWRT LAALGAGAAA GPVASVLEVD AALTAAAGVA AGTGSSTRRQ 100
    EVLRALFERL TKDEQQFLFR LVTGELRQGA LEGVMVDAIA AAAEVPAEDV 150
    RRAFMLSGKL GVTGVAAMTG GQAALAEFRL TLGTPIKPML ASPAESLDEA 200
    VAEHAEAIVE YKMDGARIQV HRQGDEVHVW TRTLREITGS VQELVDLVRA 250
    LPCESVVLDG ETLALTDAGR PRPFQDTMSR FGSTREEQVK ALLLRPYFFD 300
    CLHLDGVDLL DAPLSERNAA LRKVAGAHVI PGEVGTAGAA AVLEAAMEAG 350
    HEGVMVKDLA APYAAGRRGR AWLKVKPVHT IDLVVLAAEW GHGRRTGTLS 400
    NLHLGARDPD GGPPIMVGKT FKGMTDELLA WQTRTFQEIE THRDEWTVYV 450
    RPEVVVEIEL DSAQVSTRYP GGLALRFARV VRYRPDKDPA DADTIDTVRG 500
    LLHGDRSEGS 510
    Length:510
    Mass (Da):54,598
    Last modified:October 19, 2011 - v1
    Checksum:i1A349D55022D5068
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002896 Genomic DNA. Translation: AEK46754.1.
    CP003729 Genomic DNA. Translation: AFO81476.1.
    RefSeqiYP_005536211.1. NC_017186.1.
    YP_006554421.1. NC_018266.1.

    Genome annotation databases

    EnsemblBacteriaiAEK46754; AEK46754; RAM_41435.
    AFO81476; AFO81476; AMES_7943.
    GeneIDi12118584.
    13407471.
    KEGGiamm:AMES_7943.
    amn:RAM_41435.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002896 Genomic DNA. Translation: AEK46754.1 .
    CP003729 Genomic DNA. Translation: AFO81476.1 .
    RefSeqi YP_005536211.1. NC_017186.1.
    YP_006554421.1. NC_018266.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEK46754 ; AEK46754 ; RAM_41435 .
    AFO81476 ; AFO81476 ; AMES_7943 .
    GeneIDi 12118584.
    13407471.
    KEGGi amm:AMES_7943.
    amn:RAM_41435.

    Phylogenomic databases

    KOi K01971.

    Family and domain databases

    Gene3Di 1.10.3260.10. 1 hit.
    2.40.50.140. 1 hit.
    InterProi IPR000977. DNA_ligase_ATP-dep.
    IPR012309. DNA_ligase_ATP-dep_C.
    IPR012310. DNA_ligase_ATP-dep_cent.
    IPR016059. DNA_ligase_ATP-dep_CS.
    IPR012308. DNA_ligase_ATP-dep_N.
    IPR012340. NA-bd_OB-fold.
    [Graphical view ]
    Pfami PF04679. DNA_ligase_A_C. 1 hit.
    PF01068. DNA_ligase_A_M. 1 hit.
    PF04675. DNA_ligase_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF117018. SSF117018. 1 hit.
    SSF50249. SSF50249. 1 hit.
    TIGRFAMsi TIGR00574. dnl1. 1 hit.
    PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
    PS50160. DNA_LIGASE_A3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699."
      Verma M., Kaur J., Kumar M., Kumari K., Saxena A., Anand S., Nigam A., Ravi V., Raghuvanshi S., Khurana P., Tyagi A.K., Khurana J.P., Lal R.
      J. Bacteriol. 193:5562-5563(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S699Imported.
    2. "Complete genome sequence of Amycolatopsis mediterranei S699 based on de novo assembly via a combinatorial sequencing strategy."
      Tang B., Zhao W., Zheng H., Zhuo Y., Zhang L., Zhao G.P.
      J. Bacteriol. 194:5699-5700(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S699Imported.
    3. Biao T.
      Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: S699Imported.

    Entry informationi

    Entry nameiG0FNS9_AMYMS
    AccessioniPrimary (citable) accession number: G0FNS9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 21 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3