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G0FNS9

- G0FNS9_AMYMS

UniProt

G0FNS9 - G0FNS9_AMYMS

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Protein
DNA ligase
Gene
ligB, lig, AMES_7943, RAM_41435
Organism
Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
Name:ligBImported
Synonyms:ligImported
Ordered Locus Names:AMES_7943Imported, RAM_41435Imported
OrganismiAmycolatopsis mediterranei (strain S699) (Nocardia mediterranei)Imported
Taxonomic identifieri713604 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeAmycolatopsis
ProteomesiUP000006138: Chromosome

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

KOiK01971.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProiIPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0FNS9-1 [UniParc]FASTAAdd to Basket

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MLLSELVRAS AELAATRSRK AKIALLAELL RAAEIAELPT VIAYLTGQTA    50
QDRLGAGWRT LAALGAGAAA GPVASVLEVD AALTAAAGVA AGTGSSTRRQ 100
EVLRALFERL TKDEQQFLFR LVTGELRQGA LEGVMVDAIA AAAEVPAEDV 150
RRAFMLSGKL GVTGVAAMTG GQAALAEFRL TLGTPIKPML ASPAESLDEA 200
VAEHAEAIVE YKMDGARIQV HRQGDEVHVW TRTLREITGS VQELVDLVRA 250
LPCESVVLDG ETLALTDAGR PRPFQDTMSR FGSTREEQVK ALLLRPYFFD 300
CLHLDGVDLL DAPLSERNAA LRKVAGAHVI PGEVGTAGAA AVLEAAMEAG 350
HEGVMVKDLA APYAAGRRGR AWLKVKPVHT IDLVVLAAEW GHGRRTGTLS 400
NLHLGARDPD GGPPIMVGKT FKGMTDELLA WQTRTFQEIE THRDEWTVYV 450
RPEVVVEIEL DSAQVSTRYP GGLALRFARV VRYRPDKDPA DADTIDTVRG 500
LLHGDRSEGS 510
Length:510
Mass (Da):54,598
Last modified:October 19, 2011 - v1
Checksum:i1A349D55022D5068
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002896 Genomic DNA. Translation: AEK46754.1.
CP003729 Genomic DNA. Translation: AFO81476.1.
RefSeqiYP_005536211.1. NC_017186.1.
YP_006554421.1. NC_018266.1.

Genome annotation databases

EnsemblBacteriaiAEK46754; AEK46754; RAM_41435.
AFO81476; AFO81476; AMES_7943.
GeneIDi12118584.
13407471.
KEGGiamm:AMES_7943.
amn:RAM_41435.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002896 Genomic DNA. Translation: AEK46754.1 .
CP003729 Genomic DNA. Translation: AFO81476.1 .
RefSeqi YP_005536211.1. NC_017186.1.
YP_006554421.1. NC_018266.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEK46754 ; AEK46754 ; RAM_41435 .
AFO81476 ; AFO81476 ; AMES_7943 .
GeneIDi 12118584.
13407471.
KEGGi amm:AMES_7943.
amn:RAM_41435.

Phylogenomic databases

KOi K01971.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
InterProi IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699."
    Verma M., Kaur J., Kumar M., Kumari K., Saxena A., Anand S., Nigam A., Ravi V., Raghuvanshi S., Khurana P., Tyagi A.K., Khurana J.P., Lal R.
    J. Bacteriol. 193:5562-5563(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S699Imported.
  2. "Complete genome sequence of Amycolatopsis mediterranei S699 based on de novo assembly via a combinatorial sequencing strategy."
    Tang B., Zhao W., Zheng H., Zhuo Y., Zhang L., Zhao G.P.
    J. Bacteriol. 194:5699-5700(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S699Imported.
  3. Biao T.
    Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: S699Imported.

Entry informationi

Entry nameiG0FNS9_AMYMS
AccessioniPrimary (citable) accession number: G0FNS9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 16, 2014
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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