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Protein

Aldose 1-epimerase

Gene

galM

Organism
Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Converts alpha-aldose to the beta-anomer.UniRule annotation

Catalytic activityi

Alpha-D-glucose = beta-D-glucose.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. aldose 1-epimerase activity Source: UniProtKB-EC
  2. carbohydrate binding Source: InterPro

GO - Biological processi

  1. hexose metabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolismUniRule annotation

Enzyme and pathway databases

UniPathwayiUPA00242.

Names & Taxonomyi

Protein namesi
Recommended name:
Aldose 1-epimeraseUniRule annotation (EC:5.1.3.3UniRule annotation)
Alternative name(s):
Galactose mutarotaseUniRule annotation
Gene namesi
Name:galMImported
Ordered Locus Names:AMES_3324Imported, RAM_17100Imported
OrganismiAmycolatopsis mediterranei (strain S699) (Nocardia mediterranei)Imported
Taxonomic identifieri713604 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPseudonocardineaePseudonocardiaceaeAmycolatopsis
ProteomesiUP000006138: Chromosome

Structurei

3D structure databases

ProteinModelPortaliG0FLT1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldose epimerase family.UniRule annotation

Phylogenomic databases

KOiK01785.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0FLT1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAPELTREL FGQAGGTDVH RYTLGRPGGP VVRVLDYGGV LQSLEAPDRD
60 70 80 90 100
GRPGNVVLGY ADLDAYVANN RPEADRVFLG AVIGRFANRI AGGTFTLDGV
110 120 130 140 150
QYRVPLNNGK NSLHGGPAGF DTRIWTAAEI RDGDGVAVQL TLVSPDGDQG
160 170 180 190 200
YPGRLTAEVT YRLDARDRLR ITYRATTDAP TVVNLTNHTY WNLAGEGAGD
210 220 230 240 250
VHEHRLEIAA SRFCPTGDDL IPAGDPVPVE GTPFDFRRGA PIGARVGEPD
260 270 280 290 300
PQLVIGQGYD HNWVLDDGAP FAARAWDPAS GRLLTMWTTE PGLQFYSGNY
310 320 330 340 350
LTAALTGTGG RPYHRGAGFA LEAQHFPDSP NRPDFPSTVL RPGEVYHQET
360
VFALTTADEP PVA
Length:363
Mass (Da):39,045
Last modified:October 19, 2011 - v1
Checksum:iFAA36C1A993CF0F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002896 Genomic DNA. Translation: AEK41908.1.
CP003729 Genomic DNA. Translation: AFO76860.1.
RefSeqiYP_005531365.1. NC_017186.1.
YP_006549805.1. NC_018266.1.

Genome annotation databases

EnsemblBacteriaiAEK41908; AEK41908; RAM_17100.
AFO76860; AFO76860; AMES_3324.
GeneIDi12117600.
13413680.
KEGGiamm:AMES_3324.
amn:RAM_17100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002896 Genomic DNA. Translation: AEK41908.1.
CP003729 Genomic DNA. Translation: AFO76860.1.
RefSeqiYP_005531365.1. NC_017186.1.
YP_006549805.1. NC_018266.1.

3D structure databases

ProteinModelPortaliG0FLT1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEK41908; AEK41908; RAM_17100.
AFO76860; AFO76860; AMES_3324.
GeneIDi12117600.
13413680.
KEGGiamm:AMES_3324.
amn:RAM_17100.

Phylogenomic databases

KOiK01785.

Enzyme and pathway databases

UniPathwayiUPA00242.

Family and domain databases

Gene3Di2.70.98.10. 1 hit.
InterProiIPR018052. Ald1_epimerase_CS.
IPR015443. Aldose_1-epimerase.
IPR008183. Aldose_1/G6P_1-epimerase.
IPR011013. Gal_mutarotase_SF_dom.
IPR014718. Glyco_hydro-type_carb-bd_sub.
[Graphical view]
PfamiPF01263. Aldose_epim. 1 hit.
[Graphical view]
PIRSFiPIRSF005096. GALM. 1 hit.
SUPFAMiSSF74650. SSF74650. 1 hit.
PROSITEiPS00545. ALDOSE_1_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Whole genome sequence of the rifamycin B-producing strain Amycolatopsis mediterranei S699."
    Verma M., Kaur J., Kumar M., Kumari K., Saxena A., Anand S., Nigam A., Ravi V., Raghuvanshi S., Khurana P., Tyagi A.K., Khurana J.P., Lal R.
    J. Bacteriol. 193:5562-5563(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S699Imported.
  2. "Complete genome sequence of Amycolatopsis mediterranei S699 based on de novo assembly via a combinatorial sequencing strategy."
    Tang B., Zhao W., Zheng H., Zhuo Y., Zhang L., Zhao G.P.
    J. Bacteriol. 194:5699-5700(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S699Imported.
  3. Biao T.
    Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: S699Imported.

Entry informationi

Entry nameiG0FLT1_AMYMS
AccessioniPrimary (citable) accession number: G0FLT1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: February 4, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.