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Protein

Glutamate decarboxylase

Gene

RAM_45505

Organism
Amycolatopsis mediterranei (strain S699) (Nocardia mediterranei)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:RAM_45505Imported
OrganismiAmycolatopsis mediterranei (strain S699) (Nocardia mediterranei)Imported
Taxonomic identifieri713604 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaPseudonocardialesPseudonocardiaceaeAmycolatopsis
Proteomesi
  • UP000006138 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei277N6-(pyridoxal phosphate)lysineUniRule annotation1

Structurei

3D structure databases

ProteinModelPortaliG0FKM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

KOiK01580.
OMAiYTGRLFT.
OrthoDBiPOG091H06F5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

G0FKM5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLHQGKAGR PDRTAGTNPL YAGANPALAA GFVMPHDKLR EDSLPPDTAL
60 70 80 90 100
QLVRDELMLD GNARLNLATF VTTWMEPQAR ELMAECVDKN MIDKDEYPQT
110 120 130 140 150
AELERRCVNI LADLWHAPDP GDVMGCSTTG SSEACMLAGM ALKRRWSKLG
160 170 180 190 200
RTGKPNLVMG ANVQVCWEKF CEYWEVEPRL VPMDGDRYHL TADEAVARCD
210 220 230 240 250
ENTIGVVAIL GSTFDGSYEP VAEIAAALDS LEERTGWDIP VHVDGASGAM
260 270 280 290 300
IAPFLDPHLE WDFRLPRVAS INTSGHKYGL VYPGVGWVLW RDKAALPSEL
310 320 330 340 350
VFNVNYLGGD MPTFALNFSR PGAEVAAQYY TFVRLGREGF RAVQQASRDV
360 370 380 390 400
ALHLSSGIAS LGPFSLLTRG DQLPVFAFTT RPDVGFDVFD VSRRLRERGW
410 420 430 440 450
LVPAYTFPEN RTDLAVLRIV VRNGFTHDLA DLLLADLRRV LPELEQFGGR
460
PKDPAKATAF HH
Length:462
Mass (Da):51,110
Last modified:October 19, 2011 - v1
Checksum:iD2D44AF965447041
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002896 Genomic DNA. Translation: AEK47566.1.
RefSeqiWP_013230584.1. NC_018266.1.

Genome annotation databases

EnsemblBacteriaiAEK47566; AEK47566; RAM_45505.
KEGGiamm:AMES_8734.
amn:RAM_45505.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002896 Genomic DNA. Translation: AEK47566.1.
RefSeqiWP_013230584.1. NC_018266.1.

3D structure databases

ProteinModelPortaliG0FKM5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEK47566; AEK47566; RAM_45505.
KEGGiamm:AMES_8734.
amn:RAM_45505.

Phylogenomic databases

KOiK01580.
OMAiYTGRLFT.
OrthoDBiPOG091H06F5.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiG0FKM5_AMYMS
AccessioniPrimary (citable) accession number: G0FKM5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: September 7, 2016
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.