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Protein

Guanylate kinase

Gene

gmk

Organism
Cupriavidus necator (strain ATCC 43291 / DSM 13513 / N-1) (Ralstonia eutropha)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotationSAAS annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi26 – 33ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinaseUniRule annotationSAAS annotationImported, Transferase
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotationSAAS annotation (EC:2.7.4.8UniRule annotationSAAS annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotationImported
Ordered Locus Names:CNE_1c09030Imported
OrganismiCupriavidus necator (strain ATCC 43291 / DSM 13513 / N-1) (Ralstonia eutropha)Imported
Taxonomic identifieri1042878 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000006798 Componenti: Chromosome 1

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Structurei

3D structure databases

ProteinModelPortaliG0EYZ9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini19 – 197Guanylate kinase-likeInterPro annotationAdd BLAST179

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK00942.
OMAiYGTLKSE.
OrthoDBiPOG091H01Q4.

Family and domain databases

HAMAPiMF_00328. Guanylate_kinase. 1 hit.
InterProiView protein in InterPro
IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like_dom.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00625. Guanylate_kin. 1 hit.
SMARTiView protein in SMART
SM00072. GuKc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiView protein in PROSITE
PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.

Sequencei

Sequence statusi: Complete.

G0EYZ9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSPTPQSAPH TAIDTVYPGN LFMVVAPSGA GKSTLVNKLL SQDPAIRLSI
60 70 80 90 100
SHTTRAPRPG EQDGREYHFV TVDAFRAARD RGDFLEWAEV HGNYYATSRV
110 120 130 140 150
WIEQQMAQGN DVLLEIDWQG AQQVHQRFSN AVEIFILPPS LTALEERLKK
160 170 180 190 200
RGQDEPNVIV RRLLAAGSEM AHASESDYVI INEVFDDALE QLRNVISATR
210 220
LRFSSQKARH TELFIELGIH
Length:220
Mass (Da):24,690
Last modified:October 19, 2011 - v1
Checksum:i98CD30366190166D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002877 Genomic DNA. Translation: AEI76264.1.
RefSeqiWP_010809225.1. NC_015726.1.

Genome annotation databases

EnsemblBacteriaiAEI76264; AEI76264; CNE_1c09030.
GeneIDi34310287.
KEGGicnc:CNE_1c09030.

Similar proteinsi

Entry informationi

Entry nameiG0EYZ9_CUPNN
AccessioniPrimary (citable) accession number: G0EYZ9
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 22, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported