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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cupriavidus necator (strain ATCC 43291 / DSM 13513 / N-1) (Ralstonia eutropha)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei215UniRule annotation1
Active sitei662UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:CNE_1c28710Imported
OrganismiCupriavidus necator (strain ATCC 43291 / DSM 13513 / N-1) (Ralstonia eutropha)Imported
Taxonomic identifieri1042878 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
Proteomesi
  • UP000006798 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

G0EUD7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQHAARPHG RRTAPAAKDQ SPALGAGQGD ANGASTTESK RPATRSGTKR
60 70 80 90 100
SPKPKLSIVS SNGTAIAPTA RRTADKDVPL REDIRFLGRL LGECLREQEG
110 120 130 140 150
DAAFEVVETI RQTAVRFRRE NDRAAGAELD RLLKRLSRDQ TNQVVRAFSY
160 170 180 190 200
FSHLANIAED QHHNRRRRVH ALAGSPPQAG SLAHALEAID AAGVTGKQLR
210 220 230 240 250
KFLDEALIVP VLTAHPTEVQ RKSILDAERE IARLLAERDL PMTAREREHN
260 270 280 290 300
TAQLRAKVTT LWQTRMLRDS RLTVADEIEN ALSYYRTCFL RGIPQLMSEL
310 320 330 340 350
EEDIAAVFPA TRKRKGTPGA QPAPLAPFLQ MGSWIGGDRD GNPNVTAETL
360 370 380 390 400
EHAASQQGQM IIDWYLDEVH ALGAELSMST LMVDASPELL ALAERSPDHS
410 420 430 440 450
EHRADEPYRR ALIGIYARLA ATSKALTGHA VPRRPVAPAE PYDSAEAFAA
460 470 480 490 500
DVQVVVDSLR ANHGQALANG RIDALARAIG VFGFHLASVD MRQVSDVHEA
510 520 530 540 550
VIAELFAAAG IAPDYAALPE ARKLELLLAE LRQPRLLTLP WHEYSEQTRK
560 570 580 590 600
ELAIFAAARE LRARYGKRIA RNYIISHTET LSDLVEVMLL QKESGMLQGT
610 620 630 640 650
LGSKTDPARM ELMVIPLFET IEDLRNAAGI MQSLLDLPGF DSVIAHHGVE
660 670 680 690 700
QEVMLGYSDS NKDGGFLTST WELYKAELAL VQLFEQRQVK LRLFHGRGGT
710 720 730 740 750
VGRGGGPTYQ AILSQPPGTV NGQIRLTEQG EIINSKFANA EIGRRNLETV
760 770 780 790 800
VAATLEASLL PQQNAPRELD TFEAVMQQLS DRAFTAYRDL VYETPGFKDY
810 820 830 840 850
FFATTPITEI ADLNLGSRPA SRKLMDKKNR RIEDLRAIPW GFSWGQCRLL
860 870 880 890 900
LPGWYGFGSA VKSLLDTAPD DKARKLAVTT LRRMVKTWPF FSTLLSNMDM
910 920 930 940 950
VLAKTDLAVA SRYAQLCDDA ALRRTVFNRI SKEWHLTCEM LTLVTGHQER
960 970 980 990 1000
LADNPLLARS IKNRFAYLDP LNHLQVELLK RFRSGKDGDD IRVRRGIHLT
1010
INGVAAGLRN TG
Length:1,012
Mass (Da):112,111
Last modified:October 19, 2011 - v1
Checksum:iFD36B6708A2E6DAA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002877 Genomic DNA Translation: AEI78184.1
RefSeqiWP_013957758.1, NC_015726.1

Genome annotation databases

EnsemblBacteriaiAEI78184; AEI78184; CNE_1c28710
GeneIDi34310566
KEGGicnc:CNE_1c28710

Similar proteinsi

Entry informationi

Entry nameiG0EUD7_CUPNN
AccessioniPrimary (citable) accession number: G0EUD7
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: March 28, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health