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G0DZL2 (G0DZL2_ENTAK) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length701 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA By similarity. HAMAP-Rule MF_01858

Catalytic activity

S-adenosyl-L-methionine + guanine(2069) in 23S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(2069) in 23S rRNA. HAMAP-Rule MF_01858 SAAS SAAS000241

S-adenosyl-L-methionine + guanine(2445) in 23S rRNA = S-adenosyl-L-homocysteine + N(2)-methylguanine(2445) in 23S rRNA. HAMAP-Rule MF_01858 SAAS SAAS000241

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01858 SAAS SAAS000241.

Sequence similarities

Belongs to the methyltransferase superfamily. RlmKL family. HAMAP-Rule MF_01858

Contains 1 THUMP domain. HAMAP-Rule MF_01858

Contains THUMP domain. SAAS SAAS000241

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain43 – 154112THUMP By similarity HAMAP-Rule MF_01858

Sequences

Sequence LengthMass (Da)Tools
G0DZL2 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: A912936E9126B028

FASTA70178,843
        10         20         30         40         50         60 
MKSLFASTAR GLEELLKTEL EGLGATACQV VQGGVHFQGD TRLLYQSLMW SRLASRIMLP 

        70         80         90        100        110        120 
LGECSVYSDL DLYLGVQSIP WTEIFTTDAT FAVHFSGLNE EIRNSQYGAL KVKDAIVDSF 

       130        140        150        160        170        180 
TRKNLPRPNV DRENPDLRIN VWLNKETAHI SLDLSGEGLH LRGYRDGTGM APIKENLAAA 

       190        200        210        220        230        240 
IVMRSGWVAG TPLLDPMCGS GTLLIEAAML ATDRAPGLHR GHWGFGGWAQ HDDAIWKEVK 

       250        260        270        280        290        300 
AEAQTRARQG LAAYESRFYG SDVDERVIER ARRNARRAGI GELINFEVKD VAQLNNPLPK 

       310        320        330        340        350        360 
GPYGTVISNP PYGERLESEP ALIALHSLLG RIMKNQFGGW NLSVFSASPE LLSCLQLRAD 

       370        380        390        400        410        420 
KQFKAKNGPL DCVQKNYHLA ESEGGKPAML AEDFANRLRK NLKKFEKWAR QEGIECYRLY 

       430        440        450        460        470        480 
DADLPEYNVA IDRYGEWVVV QEYAPPKTVD AHKARQRLFD IIAATIAVLG IAPNKLVLKT 

       490        500        510        520        530        540 
RERQKGKNQY QKMAEKGDFI EVQEYNARLW VNLTDYLDTG LFLDHRIARC MLGQMSKGKD 

       550        560        570        580        590        600 
FLNLFSYTGS ASVHAGLGGA RSTTTVDMSR TYLEWAERNL RLNGLTGRAH RLMQADVLGW 

       610        620        630        640        650        660 
LRESTEQFDL IFIDPPTFSN SKRMEDAFDV QRDHIRLMTD LKRLLRKGGT IMFSNNKRGF 

       670        680        690        700 
RMDHDGLAAL GLKAQEISQK TLSQDFARNR QIHNCWLITA A 

« Hide

References

[1]"Complete sequence of Enterobacter aerogenes KCTC 2190."
Shin S.H., Kim S., Kim J.Y., Yang K.-S., Seo J.-S.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 13048 / DSM 30053 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002824 Genomic DNA. Translation: AEG97974.1.
RefSeqYP_004593253.1. NC_015663.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG97974; AEG97974; EAE_15305.
GeneID10793283.
KEGGeae:EAE_15305.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK12297.
OMANKRGFKM.

Enzyme and pathway databases

BioCycEAER1028307:GHNA-3125-MONOMER.

Family and domain databases

HAMAPMF_01858. 23SrRNA_methyltr_KL.
InterProIPR017244. 23SrRNA_methyltr_KL.
IPR002052. DNA_methylase_N6_adenine_CS.
IPR002296. N12N6_MeTrfase.
IPR000241. RNA_methylase_dom.
IPR019614. SAM-dep_methyl-trfase.
IPR004114. THUMP.
[Graphical view]
PfamPF10672. Methyltrans_SAM. 1 hit.
PF02926. THUMP. 1 hit.
PF01170. UPF0020. 1 hit.
[Graphical view]
PIRSFPIRSF037618. RNA_Mtase_bacteria_prd. 1 hit.
PRINTSPR00507. N12N6MTFRASE.
SMARTSM00981. THUMP. 1 hit.
[Graphical view]
PROSITEPS00092. N6_MTASE. 1 hit.
PS51165. THUMP. 1 hit.
PS01261. UPF0020. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0DZL2_ENTAK
AccessionPrimary (citable) accession number: G0DZL2
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 16, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)