G0DMP3 (G0DMP3_9GAMM) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Isocitrate dehydrogenase, NADP-dependent EMBL AEH14317.1
EC=1.1.1.42 EMBL AEH14317.1

Gene names

ORF Names:

Sbal117_2611 EMBL AEH14317.1

Organism

Shewanella baltica OS117 EMBL AEH14317.1

Taxonomic identifier

693970 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella › Shewanella baltica

Protein attributes

Sequence length	741 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. PIRSR PIRSR009407-3

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR009407-3 Metal-binding PIRSR PIRSR009407-3
Molecular function	Oxidoreductase EMBL AEH14317.1
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	isocitrate dehydrogenase (NADP+) activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Region	134 – 141	8	Substrate binding By similarity PIRSR PIRSR009407-2
Sites
	Metal binding	352	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	550	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Metal binding	554	1	Magnesium or manganese By similarity PIRSR PIRSR009407-3
	Binding site	147	1	Substrate By similarity PIRSR PIRSR009407-2
	Binding site	549	1	Substrate By similarity PIRSR PIRSR009407-2
	Site	257	1	Critical for catalysis By similarity PIRSR PIRSR009407-1
	Site	422	1	Critical for catalysis By similarity PIRSR PIRSR009407-1

Sequences

	Sequence		Length	Mass (Da)
	G0DMP3 [UniParc]. Last modified October 19, 2011. Version 1. Checksum: BA28276443C5D718	FASTA	741	80,354
	10 20 30 40 50 60 MKDNSSTIIY TETDEAPALA TLSLLPIIRT FTDAAGVAVE TRDISLSGRI IASFPEQLTE 70 80 90 100 110 120 AQKIGDHLTE LGELANQPEA NIIKLPNISA SIPQLKACIL ELQQKGYDIP HYPDEPKTDA 130 140 150 160 170 180 EKSIKTRYDK IKGSAVNPVL REGNSDRRAP LSVKNFAKKN PHSMGKWATD SKSHVAHMTY 190 200 210 220 230 240 GDFYGSEQSV TLSDAGSVNI VLTQKDGQEV VLKSGLKLLA GEIIDAAVLS KKALVSFYER 250 260 270 280 290 300 EIENAKAEDV LLSLHLKATM MKVSDPIMFG HAVKVFFKPV FDKHAALFAE LGVDVNNGFG 310 320 330 340 350 360 DVYAKIATLP ADSRAEVEAD IAAVYAARPA LAMVDSDKGI TNLHVPSDII IDASMPAAIR 370 380 390 400 410 420 SSGQMWGPDG QLHDTKAMIP DRCYAGIYQE TIAFCKEHGA FDPKTMGSVP NVGLMAQKAE 430 440 450 460 470 480 EYGSHDKTFE MPADGVVNVV DASGKVLMSH NVEAGDIWRM CQVKDAPIRD WVKLAVRRAR 490 500 510 520 530 540 LSNTPAVFWL DSKRAHDAQI IAKVQQYLPE HDTDGLDISI MSPEDATRLS LARIKEGKDT 550 560 570 580 590 600 ISVTGNVLRD YLTDLFPILE LGTSAKMLSI VPLMNGGGLF ETGAGGSAPK HVQQVEKEGH 610 620 630 640 650 660 LRWDSLGEFL ALAASLEHLS QTVGNPKAQV LADTLDQAIG QFLDSNKSPS RRVGELDNRG 670 680 690 700 710 720 SHFYLAMYWA QALAAQTGDE QLQAHFIPLA HALAANEQVI VAELATAQGA PVDLGGYYRL 730 740 DAAKAEKAMR PSETLNKLLI A

References

[1]

"Complete sequence of chromosome of Shewanella baltica OS117." US DOE Joint Genome Institute Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Lu M., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Hofle M., Brettar I. , Konstantinidis K., Deng J., Tiedje J., Auchtung J., Woyke T. Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: OS117 EMBL AEH14317.1.

[2]

"Genome Sequencing of Five Shewanella baltica Strains Recovered from the Oxic-Anoxic Interface of the Baltic Sea." Caro-Quintero A., Auchtung J., Deng J., Brettar I., Hofle M., Tiedje J.M., Konstantinidis K.T. J. Bacteriol. 194:1236-1236(2012) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: OS117 EMBL AEH14317.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP002811 Genomic DNA. Translation: AEH14317.1.
RefSeq	YP_006037811.1. NC_017579.1.
3D structure databases
ProteinModelPortal	G0DMP3.
SMR	G0DMP3. Positions 8-739.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AEH14317; AEH14317; Sbal117_2611.
GeneID	12634380.
KEGG	sbs:Sbal117_2611.
Phylogenomic databases
KO	K00031.
Enzyme and pathway databases
BioCyc	SBAL693970:GLK3-2662-MONOMER.
Family and domain databases
Gene3D	3.40.718.10. 3 hits.
InterPro	IPR004436. Isocitrate_DH_NADP_mono. IPR024084. IsoPropMal-DH-like_dom. [Graphical view]
Pfam	PF03971. IDH. 1 hit. [Graphical view]
PIRSF	PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMs	TIGR00178. monomer_idh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

G0DMP3_9GAMM

Accession

Primary (citable) accession number: G0DMP3

Entry history

Integrated into UniProtKB/TrEMBL:	October 19, 2011
Last sequence update:	October 19, 2011
Last modified:	May 29, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)