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G0CWS0

- G0CWS0_CORUB

UniProt

G0CWS0 - G0CWS0_CORUB

Protein

Alanine racemase

Gene

alr

Organism
Corynebacterium ulcerans (strain BR-AD22)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 23 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei36 – 361Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei135 – 1351SubstrateUniRule annotation
    Active sitei262 – 2621Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei310 – 3101Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciCULC945712:GHG6-476-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Name:alrImported
    Ordered Locus Names:CULC22_00462Imported
    OrganismiCorynebacterium ulcerans (strain BR-AD22)Imported
    Taxonomic identifieri945712 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium
    ProteomesiUP000008887: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei36 – 361N6-(pyridoxal phosphate)lysineUniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliG0CWS0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    KOiK01775.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    G0CWS0-1 [UniParc]FASTAAdd to Basket

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    MNLLEARIDL DAIAHNTHLI KDKAAAQGAQ LMCVVKADGY NHGAVEVATV    50
    MEDNGADQFG VATIREALAL REGGIESSIL SWIWSPEQDL GAAIAAGIDL 100
    AAISLAHVKA LVRASESYGE KPVRVTVKVD TGLHRSGVDK QDWEEAFCSL 150
    RDAENIQVTG VFSHFSSADE SDSSETEQQV EAFLAAIELG RSLGLELPVN 200
    HIANSPATLN RPDLYFDMVR PGLALYGHEP IPGENHGLRE AMSWVGRVTV 250
    VKPIAKGEGT SYNLTWRAEQ DGYLCVVPVG YADGLPRSAQ GHLEVTIGGR 300
    RYPQVGRVCM DQIVVNLGEN PYGVAQDDEA VILGPTGMTA TELATAIGTI 350
    NYELVCRPCG RTVRVFEHRD 370
    Length:370
    Mass (Da):39,870
    Last modified:October 19, 2011 - v1
    Checksum:i1F5BFA3AA5DAAB41
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002791 Genomic DNA. Translation: AEG83180.1.
    RefSeqiWP_013910846.1. NC_015683.1.
    YP_004629099.1. NC_015683.1.

    Genome annotation databases

    EnsemblBacteriaiAEG83180; AEG83180; CULC22_00462.
    GeneIDi10843021.
    KEGGicul:CULC22_00462.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002791 Genomic DNA. Translation: AEG83180.1 .
    RefSeqi WP_013910846.1. NC_015683.1.
    YP_004629099.1. NC_015683.1.

    3D structure databases

    ProteinModelPortali G0CWS0.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEG83180 ; AEG83180 ; CULC22_00462 .
    GeneIDi 10843021.
    KEGGi cul:CULC22_00462.

    Phylogenomic databases

    KOi K01775.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci CULC945712:GHG6-476-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BR-AD22Imported.

    Entry informationi

    Entry nameiG0CWS0_CORUB
    AccessioniPrimary (citable) accession number: G0CWS0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 23 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3