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G0CQV7 (G0CQV7_CORUL) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddlA EMBL AEG81505.1
Synonyms:ddl HAMAP-Rule MF_00047
ORF Names:CULC809_00969 EMBL AEG81505.1
OrganismCorynebacterium ulcerans 809 [Complete proteome] EMBL AEG81505.1
Taxonomic identifier945711 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeCorynebacteriaceaeCorynebacterium

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain153 – 357205ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding180 – 23556ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding3121Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3241Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding3241Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding3261Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
G0CQV7 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 6552A03B73C87B24

FASTA36239,140
        10         20         30         40         50         60 
MVVTQNPSEN PRVRVAVVYG GQSSEHSVSC VSAGAIMSHL DPEKYEVFPV GITRDGVWTV 

        70         80         90        100        110        120 
GETDATKLRT VDRVMPEVEF VREVKLSVNP RSAGEFRYED GTLYAHADVI FPALHGRFGE 

       130        140        150        160        170        180 
DGTIQGMFEL SGIPYVGTGV LSSACGMDKE YTKKLLAAEG LPVGKEVILR GDETLTDADK 

       190        200        210        220        230        240 
HMLGLPVFVK PARGGSSIGI SRVAEWDDFD AALTLAREHD TKVIVEAEIK GVEVECGVLE 

       250        260        270        280        290        300 
RADGSLIASV PAQLEDVDEG EEGFYGFDTK YLDNVVTATI PAPFDEATTK LIQSLSLEAF 

       310        320        330        340        350        360 
QALNCRGLSR VDFFITAQGP VLNEVNTMPG FTPISMYPQV FEATGIGYAE LLSHLIDQAL 


AQ 

« Hide

References

[1]"Comparative analysis of two complete Corynebacterium ulcerans genomes and detection of candidate virulence factors."
Trost E., Al-Dilaimi A., Papavasiliou P., Schneider J., Viehoever P., Burkovski A., Soares S.C., Almeida S.S., Dorella F.A., Miyoshi A., Azevedo V., Schneider M.P., Silva A., Santos C.S., Santos L.S., Sabbadini P., Dias A.A., Hirata R.Jr., Mattos-Guaraldi A.L., Tauch A.
BMC Genomics 12:383-383(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: 809 EMBL AEG81505.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002790 Genomic DNA. Translation: AEG81505.1.
RefSeqYP_005710599.1. NC_017317.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEG81505; AEG81505; CULC809_00969.
GeneID12285536.
KEGGcuc:CULC809_00969.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK01921.

Enzyme and pathway databases

BioCycCULC945711:GLC2-991-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0CQV7_CORUL
AccessionPrimary (citable) accession number: G0CQV7
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 11, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)