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G0BG51 (G0BG51_9ENTR) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Galactokinase HAMAP-Rule MF_00246
EC=2.7.1.6 HAMAP-Rule MF_00246
Alternative name(s):
Galactose kinase HAMAP-Rule MF_00246
Gene names
Name:galK HAMAP-Rule MF_00246
ORF Names:SerAS12_1264 EMBL AEF49354.1
OrganismSerratia sp. AS12 EMBL AEF49354.1
Taxonomic identifier768490 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Serratia

Protein attributes

Sequence length383 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) By similarity. HAMAP-Rule MF_00246 SAAS SAAS006206

Catalytic activity

ATP + D-galactose = ADP + alpha-D-galactose 1-phosphate. HAMAP-Rule MF_00246 SAAS SAAS006206

Pathway

Carbohydrate metabolism; galactose metabolism. SAAS SAAS006206 HAMAP-Rule MF_00246

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00246 SAAS SAAS006206.

Sequence similarities

Belongs to the GHMP kinase family. GalK subfamily. HAMAP-Rule MF_00246

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding124 – 1307ATP By similarity HAMAP-Rule MF_00246
Region34 – 374Substrate binding By similarity HAMAP-Rule MF_00246

Sites

Active site1741Proton acceptor By similarity HAMAP-Rule MF_00246
Metal binding1301Magnesium By similarity HAMAP-Rule MF_00246
Metal binding1621Magnesium By similarity HAMAP-Rule MF_00246
Binding site2231Substrate By similarity HAMAP-Rule MF_00246
Site281Transition state stabilizer By similarity HAMAP-Rule MF_00246

Sequences

Sequence LengthMass (Da)Tools
G0BG51 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: E401EC53DFC0D7A4

FASTA38341,526
        10         20         30         40         50         60 
MSLKHHTHTI FTQRFGYAPA LTIQAPGRVN LIGEHTDYND GFVLPCAIDY QTVIAGARRD 

        70         80         90        100        110        120 
DRQIRVIAAD YDGQLDQFSL DDPIVSHPDQ LWSDYVRGVI KHLQLRNANF GGADLVIAGN 

       130        140        150        160        170        180 
VPQGAGLSSS ASLEVAVGQV MQALYELPLD GVALALNGQE AENQFVGCNC GIMDQLISAL 

       190        200        210        220        230        240 
GEQDHALLID CRSLETRAVS VPENIAVVII NSNVKRGLVD SEYNTRREQC EAAARFFGVK 

       250        260        270        280        290        300 
ALRDVSPDLF FPIQHELDPI VAKRARHVIT ENDRTLAAAD ALAAGDMKLM GRLMAESHAS 

       310        320        330        340        350        360 
MRDDFAITVP PIDQLVEIVK NVIGDRGGAR MTGGGFGGCI VALMPQELVE QVRETVAREY 

       370        380 
PLQTNGLQET FYVCKASAGA GIC

« Hide

References

[1]"Complete sequence of Serratia sp. AS12."
US DOE Joint Genome Institute
Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Ovchinnikova G., Chertkov O., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Pagani I., Neupane S., Alstrom S. expand/collapse author list , Finlay R., Hogberg N., Woyke T.
Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: AS12 EMBL AEF49354.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002774 Genomic DNA. Translation: AEF49354.1.
RefSeqYP_004499711.1. NC_015566.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEF49354; AEF49354; SerAS12_1264.
GeneID10625439.
KEGGsrs:SerAS12_1264.

Phylogenomic databases

KOK00849.

Enzyme and pathway databases

UniPathwayUPA00214.

Family and domain databases

Gene3D3.30.230.10. 1 hit.
HAMAPMF_00246. Galactokinase.
InterProIPR000705. Galactokinase.
IPR022963. Galactokinase_bac.
IPR019741. Galactokinase_CS.
IPR019539. GalKase_gal-bd.
IPR013750. GHMP_kinase_C_dom.
IPR006204. GHMP_kinase_N_dom.
IPR006203. GHMP_knse_ATP-bd_CS.
IPR006206. Mevalonate/galactokinase.
IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
[Graphical view]
PfamPF10509. GalKase_gal_bdg. 1 hit.
PF08544. GHMP_kinases_C. 1 hit.
PF00288. GHMP_kinases_N. 1 hit.
[Graphical view]
PIRSFPIRSF000530. Galactokinase. 1 hit.
PRINTSPR00473. GALCTOKINASE.
PR00959. MEVGALKINASE.
SUPFAMSSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMsTIGR00131. gal_kin. 1 hit.
PROSITEPS00106. GALACTOKINASE. 1 hit.
PS00627. GHMP_KINASES_ATP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG0BG51_9ENTR
AccessionPrimary (citable) accession number: G0BG51
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 3, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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