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Protein

Bifunctional protein PutA

Gene

putA

Organism
Collimonas fungivorans (strain Ter331)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Oxidizes proline to glutamate for use as a carbon and nitrogen source.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: L-proline degradation into L-glutamate

This protein is involved in step 1 and 2 of the subpathway that synthesizes L-glutamate from L-proline.UniRule annotation
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Bifunctional protein PutA (putA)
  2. Bifunctional protein PutA (putA)
This subpathway is part of the pathway L-proline degradation into L-glutamate, which is itself part of Amino-acid degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes L-glutamate from L-proline, the pathway L-proline degradation into L-glutamate and in Amino-acid degradation.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei778 – 7781UniRule annotation
Active sitei812 – 8121UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywords - Molecular functioni

OxidoreductaseUniRule annotationImported, RepressorUniRule annotation

Keywords - Biological processi

Proline metabolismUniRule annotation, Transcription, Transcription regulationUniRule annotation

Keywords - Ligandi

DNA-bindingUniRule annotation, FADUniRule annotation, Flavoprotein, NADUniRule annotation

Enzyme and pathway databases

BioCyciCFUN1005048:GJNH-4461-MONOMER.
UniPathwayiUPA00261; UER00373.
UPA00261; UER00374.

Names & Taxonomyi

Protein namesi
Recommended name:
Bifunctional protein PutAUniRule annotation
Gene namesi
Name:putAImported
Ordered Locus Names:CFU_4418Imported
OrganismiCollimonas fungivorans (strain Ter331)Imported
Taxonomic identifieri1005048 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeCollimonas
Proteomesi
  • UP000008392 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi1005048.CFU_4418.

Structurei

3D structure databases

ProteinModelPortaliG0AEN1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini55 – 166112Pro_dh-DNA_bdgInterPro annotationAdd
BLAST
Domaini179 – 472294Pro_dhInterPro annotationAdd
BLAST
Domaini559 – 998440AldedhInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.UniRule annotation
In the C-terminal section; belongs to the aldehyde dehydrogenase family.UniRule annotation
In the N-terminal section; belongs to the proline dehydrogenase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C26. Bacteria.
COG0506. LUCA.
COG4230. LUCA.
KOiK13821.
OMAiYSLDTQE.

Family and domain databases

Gene3Di1.10.2060.10. 1 hit.
1.20.5.550. 1 hit.
3.20.20.220. 1 hit.
3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR025703. Bifunct_PutA.
IPR005933. Delta1-pyrroline-5-COlate_DH-3.
IPR029041. FAD-linked_oxidoreductase-like.
IPR024090. PRODH_PutA_dom_I.
IPR024089. PRODH_PutA_dom_I/II.
IPR024082. PRODH_PutA_dom_II.
IPR002872. Proline_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
PF01619. Pro_dh. 1 hit.
PF14850. Pro_dh-DNA_bdg. 1 hit.
[Graphical view]
PIRSFiPIRSF000197. Bifunct_PutA. 1 hit.
SUPFAMiSSF51730. SSF51730. 1 hit.
SSF53720. SSF53720. 1 hit.
SSF81935. SSF81935. 1 hit.
TIGRFAMsiTIGR01238. D1pyr5carbox3. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

G0AEN1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRAAITAAYR RDETLAVQWL LAQVQTSAGA HAASQALARK LVQAVREKRT
60 70 80 90 100
RASGVDALMH EFSLSSEEGV ALMCLAEALL RIPDHQTADR LIADKISKGD
110 120 130 140 150
WGSHLGESPS LFVNAATWGL LITGKLVATN SERGLGSALT KLIGRGGEPL
160 170 180 190 200
IRKGVDVAMR MLGNQFVTGQ TIAEALGNSR DNEKRGYRYS YDMLGEAALT
210 220 230 240 250
EEDAAAYYRS YEDAIHAIGK ASNGRGIKQG PGISVKLSAL HPRYSRAQRQ
260 270 280 290 300
RTMEELLPRL KQLLLLAKQY DIGLNIDAEE ADRLELSLDL MEALAFDPEL
310 320 330 340 350
AGFEGIGFVV QGYQKRCPFV IDYLVDLAHR SGRKFMVRLV KGAYWDSEIK
360 370 380 390 400
RAQVDGLPGF PVYTRKVYTD VSYLTCAQKL LASTDVIYPQ FATHNAHTLA
410 420 430 440 450
TIYSWAQEKK ITDYEFQCLH GMGETLYDQV VGKDMLDKPC RIYAPVGSHQ
460 470 480 490 500
TLLAYLVRRL LENGANSSFV NQIVDESVSI DSLIADPLQA AQQLGGEPHP
510 520 530 540 550
QIALPPAMYG AERKNSAGLD LSSEEVLRQI DSAFGVFGKQ QWHATPMLAE
560 570 580 590 600
LQTYSQAVRP VLNPADQRDV VGSVVEASVA DVDKALHAAS VYAMDWQTLP
610 620 630 640 650
PAERADKLDR AAALFEVHQL ELIALAIREA GKSLPNAIAE VREAVDFLRY
660 670 680 690 700
YAAQVRHTQN ALALGPVVCI SPWNFPLAIF IGEVSAALAA GNVVLAKPAE
710 720 730 740 750
QTPLIAARAV QLLHEAGVPP AALQFLPGQG DTVGATLTAD ARVKGVIFTG
760 770 780 790 800
STEVAQIISR TLAKRSLAES VDLPLIAETG GQNALIVDSS ALPEQVVQDV
810 820 830 840 850
LSSAFDSAGQ RCSALRVLCL QNDIADRTLH MLKGAMQELR IGNPDRLVTD
860 870 880 890 900
IGPVIDTDAQ GQLLAHIETM RATAKDFYQL PLPPEQHHGT FVAPTLIEIG
910 920 930 940 950
SMSELKREVF GPVLHVLRYA RNELPQLVDA INGSGYGLTL GIHSRIDETI
960 970 980 990 1000
DFIVARAHVG NIYVNRNIVG AVVGVQPFGG EGKSGTGPKA GGPLYLKRLQ
1010 1020 1030 1040 1050
RNPAVSLGAH TIHAPNPEAA NATPVLQALL SWARTHGHQR IAALGEEYMH
1060 1070 1080 1090 1100
ASWLGTSLVL PGPTGERNSL SFAPRGAILC SADNVGAMLN QLAAVFATGN
1110 1120 1130 1140 1150
LPVVEAGSSA MIPEGLPRAV RAAIRVVDQL AGSDHATRLQ LALVDGAGTV
1160 1170 1180 1190 1200
RLRPLLTALG EQSGALVPLL ETSEYASIPL WRLLAERAVC VNTTAAGGNA

SLMTLQA
Length:1,207
Mass (Da):129,846
Last modified:October 19, 2011 - v1
Checksum:i9EA53A95918A6C0B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002745 Genomic DNA. Translation: AEK64239.1.

Genome annotation databases

EnsemblBacteriaiAEK64239; AEK64239; CFU_4418.
KEGGicfu:CFU_4418.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002745 Genomic DNA. Translation: AEK64239.1.

3D structure databases

ProteinModelPortaliG0AEN1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1005048.CFU_4418.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEK64239; AEK64239; CFU_4418.
KEGGicfu:CFU_4418.

Phylogenomic databases

eggNOGiENOG4105C26. Bacteria.
COG0506. LUCA.
COG4230. LUCA.
KOiK13821.
OMAiYSLDTQE.

Enzyme and pathway databases

UniPathwayiUPA00261; UER00373.
UPA00261; UER00374.
BioCyciCFUN1005048:GJNH-4461-MONOMER.

Family and domain databases

Gene3Di1.10.2060.10. 1 hit.
1.20.5.550. 1 hit.
3.20.20.220. 1 hit.
3.40.309.10. 1 hit.
3.40.605.10. 1 hit.
InterProiIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS_CYS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR025703. Bifunct_PutA.
IPR005933. Delta1-pyrroline-5-COlate_DH-3.
IPR029041. FAD-linked_oxidoreductase-like.
IPR024090. PRODH_PutA_dom_I.
IPR024089. PRODH_PutA_dom_I/II.
IPR024082. PRODH_PutA_dom_II.
IPR002872. Proline_DH_dom.
[Graphical view]
PfamiPF00171. Aldedh. 1 hit.
PF01619. Pro_dh. 1 hit.
PF14850. Pro_dh-DNA_bdg. 1 hit.
[Graphical view]
PIRSFiPIRSF000197. Bifunct_PutA. 1 hit.
SUPFAMiSSF51730. SSF51730. 1 hit.
SSF53720. SSF53720. 1 hit.
SSF81935. SSF81935. 1 hit.
TIGRFAMsiTIGR01238. D1pyr5carbox3. 1 hit.
PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Collimonas fungivorans Ter331."
    Leveau J.H.
    Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ter331Imported.

Entry informationi

Entry nameiG0AEN1_COLFT
AccessioniPrimary (citable) accession number: G0AEN1
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 11, 2016
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.