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G0ACY7

- G0ACY7_COLFT

UniProt

G0ACY7 - G0ACY7_COLFT

Protein

Isocitrate dehydrogenase [NADP]

Gene

icdA

Organism
Collimonas fungivorans (strain Ter331)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 16 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation
    Binds 1 magnesium or manganese ion per subunit By similarity.

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotationImported

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciCFUN1005048:GJNH-3290-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdAImported
    Ordered Locus Names:CFU_3268Imported
    OrganismiCollimonas fungivorans (strain Ter331)Imported
    Taxonomic identifieri1005048 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesOxalobacteraceaeCollimonas
    ProteomesiUP000008392: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    KOiK00031.
    OMAiCLRPIRY.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    G0ACY7-1 [UniParc]FASTAAdd to Basket

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    MSQHIKVPAE GKKITVNADF SINVPDNPII PYIEGDGTGV DISPVMIKVV    50
    DAAVSKAYAG KRKISWMEVF AGEKSTKVYG PDVWLPEETL AAIKDYVVSI 100
    KGPLTTPVGG GIRSLNVALR QELDLYVCLR PVRYFKGVPS PVREPEKTDM 150
    VIFRENSEDI YAGIEWQEGS DGAKKLIEFL IKEMGVKKIR FPDTSGIGVK 200
    PVSREGTERL VRKAIQYAID NDKPSVTIVH KGNIMKFTEG GFRDWAYALA 250
    QKEFGAELID GGPWAKFKNP KTGREIIVKD SIADAFLQQI LLRPNEYSVI 300
    ATLNLNGDYI SDALAAQVGG IGIAPGANLS DSVAMFEATH GTAPKYAGKD 350
    YVNPGSLILS AEMMLRHMGW VEAADLIIES MQKSITSKKV TYDFARLMEG 400
    ATQVSCSGFG EVLIENM 417
    Length:417
    Mass (Da):45,601
    Last modified:October 19, 2011 - v1
    Checksum:i185204F826785EBD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002745 Genomic DNA. Translation: AEK63092.1.
    RefSeqiWP_014007244.1. NC_015856.1.
    YP_004753915.1. NC_015856.1.

    Genome annotation databases

    EnsemblBacteriaiAEK63092; AEK63092; CFU_3268.
    GeneIDi10993975.
    KEGGicfu:CFU_3268.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002745 Genomic DNA. Translation: AEK63092.1 .
    RefSeqi WP_014007244.1. NC_015856.1.
    YP_004753915.1. NC_015856.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEK63092 ; AEK63092 ; CFU_3268 .
    GeneIDi 10993975.
    KEGGi cfu:CFU_3268.

    Phylogenomic databases

    KOi K00031.
    OMAi CLRPIRY.

    Enzyme and pathway databases

    BioCyci CFUN1005048:GJNH-3290-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Collimonas fungivorans Ter331."
      Leveau J.H.
      Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Ter331Imported.

    Entry informationi

    Entry nameiG0ACY7_COLFT
    AccessioniPrimary (citable) accession number: G0ACY7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 16 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3