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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylomonas methanica (strain MC09)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei147UniRule annotation1
Active sitei591UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMMET857087:G1GY2-3266-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Metme_3258Imported
OrganismiMethylomonas methanica (strain MC09)Imported
Taxonomic identifieri857087 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylomonas
Proteomesi
  • UP000008888 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi857087.Metme_3258

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
KOiK01595
OMAiGPTHRFI
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

G0A5C4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRTPEYDDK TLRANIRLLK GMLDNVLKNQ ASHQVAEIVE QLQRQFTVLQ
60 70 80 90 100
RDNNPAKRQQ ILKTLHNLPA ETLSEVIRAF SLYFSLLNIA EESTQLQHRR
110 120 130 140 150
HQIEKNKHYW RGSFHDTLLA FKNAGISAEQ LQPLLDDLHY LPVMTAHPTE
160 170 180 190 200
AKRRTVRGAL RSVFVSHEKL QNSGIKGYFR DVALERLQSQ IQLLWKTDEV
210 220 230 240 250
RAHSMGVIDE IDSGLFYFPL SLFEATAQVY RNFQRALVDV YGSDAASKVN
260 270 280 290 300
IPSFLNFGSW IGGDRDGNPN VKPHTTALAL RLQARTITRE YLRRIDILLE
310 320 330 340 350
QLAYSHGMCQ PTEAFLQSLQ NDRDLLGDTA ITLERNYLQE PYRHKLALMK
360 370 380 390 400
FRMHRRMELL EQRIAGDSSQ SDDQAYNNIQ TFHADLCLIR ESLSSHGDQA
410 420 430 440 450
IADRDLQDLI RLVDIFGFYL MQLDVRQEST RHSQAVAEIL SAGLGIDYLS
460 470 480 490 500
MDEDQRMQVL SEAIAIPGGL GYDASELSAA TVETLDVFQV MAQMRREIGN
510 520 530 540 550
DCFSRYVISM THSASHIMEV LLLAAQNGLA GRISGQWYCH IGVSPLFETI
560 570 580 590 600
DDLNHIDGVL RSLLSQPAYR ALLEASGLRQ EVMLGYSDSC KDGGILASAW
610 620 630 640 650
GLYRAQQQVT AISDDVGIPC RLFHGRGGTI GRGGGPTHEA ILAQPPATVR
660 670 680 690 700
GQIKFTEQGE VLFYRYNNME TAIYELTMGI TGLMKASVSL IQPVEPDRPD
710 720 730 740 750
NLQLMGELAQ LGERSYRQLT EHTPGFLDYF YEATPVQEIG QLNIGSRPSH
760 770 780 790 800
RKKADRSKYS VRAIAWVFAW AQSRQTFPAW YGIGSSLESY CAGNPERLQA
810 820 830 840 850
LRELYKNWPF FRNLLSNAQM ALSKSDMTIA EEYSSLCSDP EAGKRVHGLI
860 870 880 890 900
AGEHRRCVDW VLEIAECDQL LAENPELAAS LRRRNDYLGP LNYMQAGLLR
910 920 930
ALNEDEDANG QSRWMNPLLR TINAIAAGMR NTG
Length:933
Mass (Da):105,347
Last modified:October 19, 2011 - v1
Checksum:iDA41ADDFB161FC51
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002738 Genomic DNA Translation: AEG01630.1
RefSeqiWP_013819857.1, NC_015572.1

Genome annotation databases

EnsemblBacteriaiAEG01630; AEG01630; Metme_3258
KEGGimmt:Metme_3258

Similar proteinsi

Entry informationi

Entry nameiG0A5C4_METMM
AccessioniPrimary (citable) accession number: G0A5C4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: March 28, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health