Skip Header

Contribute Send feedback
Read comments (?) or add your own

F9ZTE5 (F9ZTE5_ACICS) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Lysine--tRNA ligase RuleBase RU000336 HAMAP-Rule MF_00252
EC=6.1.1.6 RuleBase RU000336 HAMAP-Rule MF_00252
Alternative name(s):
Lysyl-tRNA synthetase HAMAP-Rule MF_00252
Gene names
Name:lysS HAMAP-Rule MF_00252
Ordered Locus Names:Atc_0315 EMBL AEK56966.1
OrganismAcidithiobacillus caldus (strain SM-1) [Complete proteome] [HAMAP]
Taxonomic identifier990288 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Acidithiobacillales › Acidithiobacillaceae › Acidithiobacillus ›

Protein attributes

Sequence length495 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys). SAAS SAAS002313 HAMAP-Rule MF_00252

Cofactor

Binds 3 magnesium ions per subunit By similarity. HAMAP-Rule MF_00252

Subunit structure

Homodimer By similarity. SAAS SAAS002313 HAMAP-Rule MF_00252

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00252.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. RuleBase RU003746 HAMAP-Rule MF_00252

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding4041Magnesium 1 By similarity HAMAP-Rule MF_00252
Metal binding4111Magnesium 1 By similarity HAMAP-Rule MF_00252
Metal binding4111Magnesium 2 By similarity HAMAP-Rule MF_00252

Sequences

Sequence LengthMass (Da)Tools
F9ZTE5 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: 57DE48023AE8D394

FASTA49556,202
        10         20         30         40         50         60 
MDQELNDQMQ VRRHKLERWR EQGAAYPNGF RRDAEAAELH RRYDQSDAAE LDAQAVQAHL 

        70         80         90        100        110        120 
GGRLMSRRIM GKASFADLQD GSGRLQLFFS RDELGEDAYA QFKELDLGDV IGVGGQLFRT 

       130        140        150        160        170        180 
RTGELSLRVA SFTLLAKALR PLPEKWHGLS DPETRFRQRY VDLIVTESTR RTFRIRSQTV 

       190        200        210        220        230        240 
AALRTVLSND GFIEVETPMM QPIPGGATAR PFITHHHALD MTLYLRIAPE LYLKRLVVGG 

       250        260        270        280        290        300 
FERVFEINRN FRNEGVSTRH NPEFTMLEWY ETYADYTMAM DRCETLIRAA AQAALGSTDI 

       310        320        330        340        350        360 
HYQGLAIHLG EPFARLGVAE AVRRYHPDLA HKDLRDAGVL GDKLRELGHP CPADWGWGKR 

       370        380        390        400        410        420 
LVELFEKTVE PRLEQPTFIT EYPLEVSPLA RRCSADPELT DRFELFIAGR ELANGFSELN 

       430        440        450        460        470        480 
DPDDQAARFR AQVAAKEAGD EEAMFFDADY IRALEYGMPP TAGVGLGVDR LVMLLADQPS 

       490 
IREVILFPHL RPEQT

« Hide

References

[1]"Unraveling the Acidithiobacillus caldus complete genome and its central metabolisms for carbon assimilation."
You X.Y., Guo X., Zheng H.J., Zhang M.J., Liu L.J., Zhu Y.Q., Zhu B., Wang S.Y., Zhao G.P., Poetsch A., Jiang C.Y., Liu S.J.
J. Genet. Genomics 38:243-252(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SM-1 EMBL AEK56966.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002573 Genomic DNA. Translation: AEK56966.1.
RefSeqYP_004747666.1. NC_015850.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEK56966; AEK56966; Atc_0315.
GeneID10988103.
KEGGacu:Atc_0315.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK04567.

Enzyme and pathway databases

BioCycACAL990288:GJBS-317-MONOMER.

Family and domain databases

Gene3D2.40.50.140. 1 hit.
HAMAPMF_00252. Lys_tRNA_synth_class2.
InterProIPR004364. aa-tRNA-synt_II.
IPR018150. aa-tRNA-synt_II-like.
IPR006195. aa-tRNA-synth_II.
IPR002313. Lys-tRNA-ligase_II.
IPR018149. Lys-tRNA-synth_II_C.
IPR012340. NA-bd_OB-fold.
IPR004365. NA-bd_OB_tRNA-helicase.
[Graphical view]
PANTHERPTHR22594. PTHR22594. 1 hit.
PTHR22594:SF4. PTHR22594:SF4. 1 hit.
PfamPF00152. tRNA-synt_2. 1 hit.
PF01336. tRNA_anti. 1 hit.
[Graphical view]
PRINTSPR00982. TRNASYNTHLYS.
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMsTIGR00499. lysS_bact. 1 hit.
PROSITEPS50862. AA_TRNA_LIGASE_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF9ZTE5_ACICS
AccessionPrimary (citable) accession number: F9ZTE5
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: April 3, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info