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F9ZRS3 (F9ZRS3_ACICS) Unreviewed, UniProtKB/TrEMBL

Last modified October 16, 2013. Version 12. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Isocitrate dehydrogenase [NADP] RuleBase RU004446

EC=1.1.1.42 RuleBase RU004446
Gene names
Ordered Locus Names:Atc_2440 EMBL AEK59088.1
OrganismAcidithiobacillus caldus (strain SM-1) [Complete proteome] [HAMAP] EMBL AEK59088.1
Taxonomic identifier990288 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus

Protein attributes

Sequence length424 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH. RuleBase RU004446

Cofactor

Binds 1 magnesium or manganese ion per subunit By similarity. RuleBase RU004446

Sequence similarities

Belongs to the isocitrate and isopropylmalate dehydrogenases family. RuleBase RU004443

Sequences

Sequence LengthMass (Da)Tools
F9ZRS3 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: C6ECB6ABE0389E92

FASTA42445,501
        10         20         30         40         50         60 
MSGGSLIRWA AGRLEVPDRP IIPFIEGDGI GVDVTPAMRR VVDAAVAKAY GGARAIVWRE 

        70         80         90        100        110        120 
LLAGQKAVAE LGADQILPEA TLAAIREHHV AIKGPLETPV GTGMRSLNVA LRQELDLYVC 

       130        140        150        160        170        180 
QRPVRYFRGT PSPLREPEKV DMVIFRENSE DIYAGIEWPA ESPEARRLIA FLREEMGVRK 

       190        200        210        220        230        240 
IRFPESSAIG IKPVSREGSE RLIRRAIAYA LAQGKPSVTL VHKGNIMKFT EGGFRDWGYA 

       250        260        270        280        290        300 
LAEREFGEQV FTWRQKTALA KSEGKAAAEA AEKAAVAAGK LIVKDVIADN FLQQILLRPE 

       310        320        330        340        350        360 
LYSVVATLNL NGDYLSDALA AEVGGIGMAP GANLSDSHAI FEATHGTAPD IAGLGRANPS 

       370        380        390        400        410        420 
SLILSAVMLL EHIGWPEAAE RILAAMEATI GAGEVTADLA ALRGDVPALS TAEFTAALCR 


RVEA 

« Hide

References

[1]"Unraveling the Acidithiobacillus caldus complete genome and its central metabolisms for carbon assimilation."
You X.Y., Guo X., Zheng H.J., Zhang M.J., Liu L.J., Zhu Y.Q., Zhu B., Wang S.Y., Zhao G.P., Poetsch A., Jiang C.Y., Liu S.J.
J. Genet. Genomics 38:243-252(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SM-1 EMBL AEK59088.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002573 Genomic DNA. Translation: AEK59088.1.
RefSeqYP_004749790.1. NC_015850.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEK59088; AEK59088; Atc_2440.
GeneID10990225.
KEGGacu:Atc_2440.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00031.

Enzyme and pathway databases

BioCycACAL990288:GJBS-2477-MONOMER.

Family and domain databases

Gene3D3.40.718.10. 1 hit.
InterProIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR004439. Isocitrate_DH_NADP_dimer_prok.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERPTHR11835. PTHR11835. 1 hit.
PfamPF00180. Iso_dh. 1 hit.
[Graphical view]
TIGRFAMsTIGR00183. prok_nadp_idh. 1 hit.
PROSITEPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF9ZRS3_ACICS
AccessionPrimary (citable) accession number: F9ZRS3
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: October 16, 2013
This is version 12 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)