F9ZLP0F9ZLP0_ACICSRibulose bisphosphate carboxylase large chainRuBisCO large subunit4.1.1.39cbbLAtc_0926Acidithiobacillus caldus (strain SM-1)BacteriaPseudomonadotaAcidithiobacilliaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillusUnraveling the Acidithiobacillus caldus complete genome and its central metabolisms for carbon assimilation.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.2 (2R)-3-phosphoglycerate + 2 H(+) = CO2 + D-ribulose 1,5-bisphosphate + H2OD-ribulose 1,5-bisphosphate + O2 = (2R)-3-phosphoglycerate + 2-phosphoglycolate + 2 H(+)Mg(2+)Binds 1 Mg(2+) ion per subunit.Heterohexadecamer of 8 large chains and 8 small chains.The basic functional RuBisCO is composed of a large chain homodimer in a 'head-to-tail' conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric 'cap' on each end of the 'barrel'.Belongs to the RuBisCO large chain family. Type I subfamily.Lacks conserved residue(s) required for the propagation of feature annotation.Calvin cycleCarbon dioxide fixationLyaseMagnesiumMetal-bindingMonooxygenaseOxidoreductaseReference proteomesubstratesubstratesubstrateMg(2+)Mg(2+)Mg(2+)substratesubstratesubstrateMAGKYEAGVKEYRHTYWAPDYVPLDSDILACFKIVPQPGVDREEAAAAVAAESSTGTWTTVWTDLLTDMDYYKGRAYRIEDVPGDDTAFYAFIAYPIDLFEEGSVVNVFTSLVGNVFGFKAVRSLRLEDVRFPLHYVMTCNGPAHGIQVERDKMDKYGRPLLGCTIKPKLGLSAKNYGRAVYEALRGGLDFTKDDENVNSQPFMRWRDRFLFVADAIRNAEAQTGERKGHYLNVTAPSPEEMYERAEFAKELGMPIIMHDFLTGGFCANTGLARWCRKNGVLLHIHRAMHAVIDRNPHHGIHFRVLTKALRLSGGDHLHTGTVVGKLEGDRASTLGWIDLLRESYIPEDRSRGIFFDQDWGSMPGAFAVASGGIHVWHMPALVNIFGDDSVLQFGGGTLGHPWGNAAGAAANRVALEACVEARNRGVEIEKEGKEVLMNAARHSPELKIALETWKEIKFEFDTVDKLDVQNR
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