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F9ZJ56 (F9ZJ56_9PROT) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tyrosine--tRNA ligase HAMAP-Rule MF_02007
EC=6.1.1.1 HAMAP-Rule MF_02007
Alternative name(s):
Tyrosyl-tRNA synthetase HAMAP-Rule MF_02007
Gene names
Name:tyrS HAMAP-Rule MF_02007
ORF Names:NAL212_2811 EMBL ADZ27598.1
OrganismNitrosomonas sp. AL212 EMBL ADZ27598.1
Taxonomic identifier153948 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Nitrosomonadales › Nitrosomonadaceae › Nitrosomonas

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr) By similarity. HAMAP-Rule MF_02007 SAAS SAAS002307

Catalytic activity

ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr). HAMAP-Rule MF_02007 SAAS SAAS002307

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_02007 SAAS SAAS002307

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_02007.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. HAMAP-Rule MF_02007

Contains 1 S4 RNA-binding domain. HAMAP-Rule MF_02007 SAAS SAAS002307

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain338 – 39962S4 RNA-binding By similarity HAMAP-Rule MF_02007
Motif43 – 5210"HIGH" region By similarity HAMAP-Rule MF_02007
Motif227 – 2315"KMSKS" region By similarity HAMAP-Rule MF_02007

Sites

Binding site2301ATP By similarity HAMAP-Rule MF_02007

Sequences

Sequence LengthMass (Da)Tools
F9ZJ56 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: F1F78D3EC229D59E

FASTA40044,795
        10         20         30         40         50         60 
MNTSIKSQLE IIKRGSQELL VETELEAKLV SGHPLRVKAG FDPTAPDLHL GHTVLLNKLR 

        70         80         90        100        110        120 
QLQVMGHHIL FLIGDFTGMI GDPSGKNSTR PPLTREQVAE NAQSYTTQVF KILNPDQTEV 

       130        140        150        160        170        180 
VFNSTWMGKM DAADLIKLAA THTVARMLER DDFDKRYRNN QAIAIHEFLY PLIQGYDSVA 

       190        200        210        220        230        240 
LKADLELGGT DQKFNLLMGR ELQKHFGQAQ QCILTMPLLE GLDGVNKMSK SLNNYVGITE 

       250        260        270        280        290        300 
SPAEIFGKLM SVSDQLMWRY LELLSFESLQ TIQKWREEVA AGRNPRDIKV ILAQEMVTRF 

       310        320        330        340        350        360 
HNRTSAEDAL ADFEARFKHG ALPEEIPEKI IQAPGSEIPL VQVLKQTGLT ASTSEALRMI 

       370        380        390        400 
EQGAVKLNNE KITDKSIQIM RGASVVIQVG KRKFAKAIIH

« Hide

References

[1]"Complete sequence of chromosome of Nitrosomonas sp. AL212."
Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Chertkov O., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Suwa Y. expand/collapse author list , Klotz M.G., Bollmann A., Stein L.Y., Laanbroek H.J., Arp D.J., Norton J.M., Woyke T.
Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: AL212 EMBL ADZ27598.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP002552 Genomic DNA. Translation: ADZ27598.1.
RefSeqYP_004295760.1. NC_015222.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADZ27598; ADZ27598; NAL212_2811.
GeneID10299352.
KEGGnit:NAL212_2811.

Phylogenomic databases

KOK01866.

Enzyme and pathway databases

BioCycNSP153948:GHZ8-2688-MONOMER.

Family and domain databases

Gene3D3.10.290.10. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_02007. Tyr_tRNA_synth_type2.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002942. S4_RNA-bd.
IPR002307. Tyr-tRNA-ligase.
IPR024088. Tyr-tRNA-ligase_bac-type.
IPR024108. Tyr-tRNA-ligase_bac_2.
[Graphical view]
PANTHERPTHR11766. PTHR11766. 1 hit.
PfamPF01479. S4. 1 hit.
PF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSPR01040. TRNASYNTHTYR.
SMARTSM00363. S4. 1 hit.
[Graphical view]
TIGRFAMsTIGR00234. tyrS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
PS50889. S4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF9ZJ56_9PROT
AccessionPrimary (citable) accession number: F9ZJ56
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: May 29, 2013
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info