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F9YZ00

- F9YZ00_PROAA

UniProt

F9YZ00 - F9YZ00_PROAA

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Protein
Submitted name:

Isocitrate dehydrogenase (NADP)

Gene

icd

Organism
Propionibacterium acnes 266
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Cofactori

Binds 1 magnesium or manganese ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei143 – 1431SubstrateUniRule annotation
Sitei252 – 2521Critical for catalysis
Metal bindingi347 – 3471Magnesium or manganeseUniRule annotation
Sitei417 – 4171Critical for catalysisUniRule annotation
Binding sitei541 – 5411SubstrateUniRule annotation
Metal bindingi542 – 5421Magnesium or manganeseUniRule annotation
Metal bindingi546 – 5461Magnesium or manganeseUniRule annotation

GO - Molecular functioni

  1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Keywords - Ligandi

MagnesiumUniRule annotation, Metal-bindingUniRule annotation

Enzyme and pathway databases

BioCyciPACN909952:GLIJ-1802-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Isocitrate dehydrogenase (NADP)Imported (EC:1.1.1.42Imported)
Gene namesi
Name:icdImported
ORF Names:PAZ_c18100Imported
OrganismiPropionibacterium acnes 266Imported
Taxonomic identifieri909952 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium
ProteomesiUP000009069: Chromosome

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni130 – 1378Substrate bindingUniRule annotation

Phylogenomic databases

KOiK00031.

Family and domain databases

Gene3Di3.40.718.10. 3 hits.
InterProiIPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PfamiPF03971. IDH. 1 hit.
[Graphical view]
PIRSFiPIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

Sequencei

Sequence statusi: Complete.

F9YZ00 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPTIVWTKID EAPALASYSL LPIVEGFLDG SGIDITTSDI SLAGRILAQF
60 70 80 90 100
PDRLNEDQKV ADHLAELGEL TGSPDANIIK LPNISASVPQ LKAAIAELQS
110 120 130 140 150
QGYELPDFPD KPSTDEEREI AARYATVLGS AVNPVLRQGN SDRRAPTAVK
160 170 180 190 200
AYAKAHPHRM GQWTDQVKAR VAHMDHGDFF DHEESFVSRG QDLDVVLIGT
210 220 230 240 250
DGSETTLASG IKTLDGEIVD ATFMSVDALD EFYASSLAQA NEEDLLWSVH
260 270 280 290 300
LKATMMKVSD PVLFGHAVRT FLVDVFDKYG DDLNSVGVNP DLGLGDLYTR
310 320 330 340 350
LEKLPAERAT AIKAAIDSAF AARPALAMVD SDNGITNLHA GNLVIIDASM
360 370 380 390 400
PTVVRDSGCM WNAEGKRQET LACIPDRSYA TMYAAIMDDC REHGALDPAT
410 420 430 440 450
MGDVPNVGLM AQKAEEYGSH PTTFIVPHDG RVEVRCGDEV LTNQQVEAGD
460 470 480 490 500
VWRMSRVRDI PVRDWVRLAI ERARITNTPA VFWLDKNRAH DARVIEKVKA
510 520 530 540 550
YLPEHEGLDI RILAPADAMK FTLARIRRGE DTISVTGNVL RDYLTDVFPI
560 570 580 590 600
LEIGTSAKML SVVPLLAGGG LFETGAGGSA PKHVAQFVAE DYLRWDSLGE
610 620 630 640 650
FCALGACLEH IDQTSEGTKA GILAATLDKA IGAFLENDRS PARKLGQSDN
660 670 680 690 700
RGSHYWLARY WASELAAQHD DAELADRFSD VATELAARED QILKELNGVQ
710 720 730
GSPVDMGGYY HPDEELVAEA MRPSTTFNAI IESL
Length:734
Mass (Da):79,939
Last modified:October 19, 2011 - v1
Checksum:i5F5479981DA082A8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002409 Genomic DNA. Translation: AEE72951.1.
RefSeqiYP_005942982.1. NC_017534.1.

Genome annotation databases

EnsemblBacteriaiAEE72951; AEE72951; PAZ_c18100.
GeneIDi12533596.
KEGGipaw:PAZ_c18100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002409 Genomic DNA. Translation: AEE72951.1 .
RefSeqi YP_005942982.1. NC_017534.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEE72951 ; AEE72951 ; PAZ_c18100 .
GeneIDi 12533596.
KEGGi paw:PAZ_c18100.

Phylogenomic databases

KOi K00031.

Enzyme and pathway databases

BioCyci PACN909952:GLIJ-1802-MONOMER.

Family and domain databases

Gene3Di 3.40.718.10. 3 hits.
InterProi IPR004436. Isocitrate_DH_NADP_mono.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view ]
Pfami PF03971. IDH. 1 hit.
[Graphical view ]
PIRSFi PIRSF009407. IDH_monmr. 1 hit.
TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 266Imported.

Entry informationi

Entry nameiF9YZ00_PROAA
AccessioniPrimary (citable) accession number: F9YZ00
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: October 29, 2014
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3