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F9YU51

- F9YU51_CAPCC

UniProt

F9YU51 - F9YU51_CAPCC

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Protein
Thymidine kinase
Gene
tdk, Ccan_20530
Organism
Capnocytophaga canimorsus (strain 5)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei139 – 1391Proton acceptor By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi66 – 738ATP By similarityUniRule annotation
Nucleotide bindingi138 – 1414ATP By similarityUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. thymidine kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationsImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciCCAN860228:GH4O-2108-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Ccan_20530Imported
OrganismiCapnocytophaga canimorsus (strain 5)Imported
Taxonomic identifieri860228 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCapnocytophaga
ProteomesiUP000008895: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

KOiK00857.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F9YU51-1 [UniParc]FASTAAdd to Basket

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MISKVFTNYI KNNKSLIYNT ILSLLVKNPS EIQKNTYFCE QYNSIMFLEN    50
TTNYSEKFGW IEVICGSMFS GKTEELIRRL RRAQFAKQKV EIFKPAFDTR 100
YDDVMVVSHN ANEIRSTPVP AAANIMLLAD GCDVIGIDEA QFFDDEIVTV 150
CNDLANRGMR VIVAGLDMDF KGKPFGPMPA LMATAEYVTK VHAVCTRTGN 200
LANFSYRKSA NENVFLLGEQ EAYEPLSRAA YFKAMKEKK 239
Length:239
Mass (Da):27,104
Last modified:October 19, 2011 - v1
Checksum:i7344888EC2AC8999
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002113 Genomic DNA. Translation: AEK24169.1.
RefSeqiWP_013998153.1. NC_015846.1.
YP_004741276.1. NC_015846.1.

Genome annotation databases

EnsemblBacteriaiAEK24169; AEK24169; Ccan_20530.
GeneIDi10981053.
KEGGiccm:Ccan_20530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP002113 Genomic DNA. Translation: AEK24169.1 .
RefSeqi WP_013998153.1. NC_015846.1.
YP_004741276.1. NC_015846.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AEK24169 ; AEK24169 ; Ccan_20530 .
GeneIDi 10981053.
KEGGi ccm:Ccan_20530.

Phylogenomic databases

KOi K00857.

Enzyme and pathway databases

BioCyci CCAN860228:GH4O-2108-MONOMER.

Family and domain databases

HAMAPi MF_00124. Thymidine_kinase.
InterProi IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020634. Thymidine_kinase_subgr.
[Graphical view ]
PANTHERi PTHR11441. PTHR11441. 1 hit.
Pfami PF00265. TK. 1 hit.
[Graphical view ]
PIRSFi PIRSF035805. TK_cell. 1 hit.
SUPFAMi SSF52540. SSF52540. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the dog commensal and human pathogen Capnocytophaga canimorsus strain 5."
    Manfredi P., Pagni M., Cornelis G.R.
    J. Bacteriol. 193:5558-5559(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 5.

Entry informationi

Entry nameiF9YU51_CAPCC
AccessioniPrimary (citable) accession number: F9YU51
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: September 3, 2014
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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