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F9YU51

- F9YU51_CAPCC

UniProt

F9YU51 - F9YU51_CAPCC

Protein

Thymidine kinase

Gene

tdk

Organism
Capnocytophaga canimorsus (strain 5)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 20 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei139 – 1391Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi66 – 738ATPUniRule annotation
    Nucleotide bindingi138 – 1414ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. thymidine kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. DNA replication Source: UniProtKB-KW

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Biological processi

    DNA synthesisUniRule annotationSAAS annotation

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCCAN860228:GH4O-2108-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
    Gene namesi
    Name:tdkUniRule annotation
    Ordered Locus Names:Ccan_20530Imported
    OrganismiCapnocytophaga canimorsus (strain 5)Imported
    Taxonomic identifieri860228 [NCBI]
    Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCapnocytophaga
    ProteomesiUP000008895: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the thymidine kinase family.UniRule annotation

    Phylogenomic databases

    KOiK00857.

    Family and domain databases

    HAMAPiMF_00124. Thymidine_kinase.
    InterProiIPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view]
    PANTHERiPTHR11441. PTHR11441. 1 hit.
    PfamiPF00265. TK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF035805. TK_cell. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    F9YU51-1 [UniParc]FASTAAdd to Basket

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    MISKVFTNYI KNNKSLIYNT ILSLLVKNPS EIQKNTYFCE QYNSIMFLEN    50
    TTNYSEKFGW IEVICGSMFS GKTEELIRRL RRAQFAKQKV EIFKPAFDTR 100
    YDDVMVVSHN ANEIRSTPVP AAANIMLLAD GCDVIGIDEA QFFDDEIVTV 150
    CNDLANRGMR VIVAGLDMDF KGKPFGPMPA LMATAEYVTK VHAVCTRTGN 200
    LANFSYRKSA NENVFLLGEQ EAYEPLSRAA YFKAMKEKK 239
    Length:239
    Mass (Da):27,104
    Last modified:October 19, 2011 - v1
    Checksum:i7344888EC2AC8999
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002113 Genomic DNA. Translation: AEK24169.1.
    RefSeqiWP_013998153.1. NC_015846.1.
    YP_004741276.1. NC_015846.1.

    Genome annotation databases

    EnsemblBacteriaiAEK24169; AEK24169; Ccan_20530.
    GeneIDi10981053.
    KEGGiccm:Ccan_20530.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002113 Genomic DNA. Translation: AEK24169.1 .
    RefSeqi WP_013998153.1. NC_015846.1.
    YP_004741276.1. NC_015846.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEK24169 ; AEK24169 ; Ccan_20530 .
    GeneIDi 10981053.
    KEGGi ccm:Ccan_20530.

    Phylogenomic databases

    KOi K00857.

    Enzyme and pathway databases

    BioCyci CCAN860228:GH4O-2108-MONOMER.

    Family and domain databases

    HAMAPi MF_00124. Thymidine_kinase.
    InterProi IPR027417. P-loop_NTPase.
    IPR001267. Thymidine_kinase.
    IPR020634. Thymidine_kinase_subgr.
    [Graphical view ]
    PANTHERi PTHR11441. PTHR11441. 1 hit.
    Pfami PF00265. TK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF035805. TK_cell. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the dog commensal and human pathogen Capnocytophaga canimorsus strain 5."
      Manfredi P., Pagni M., Cornelis G.R.
      J. Bacteriol. 193:5558-5559(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 5Imported.

    Entry informationi

    Entry nameiF9YU51_CAPCC
    AccessioniPrimary (citable) accession number: F9YU51
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 20 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3