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Protein

Thymidine kinase

Gene

tdk

Organism
Capnocytophaga canimorsus (strain 5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei139Proton acceptorUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi66 – 73ATPUniRule annotation8
Nucleotide bindingi138 – 141ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationImported, Transferase

Keywords - Biological processi

DNA synthesisUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:Ccan_20530Imported
OrganismiCapnocytophaga canimorsus (strain 5)Imported
Taxonomic identifieri860228 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesFlavobacteriaceaeCapnocytophaga
Proteomesi
  • UP000008895 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi860228.Ccan_20530.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107T8J. Bacteria.
COG1435. LUCA.
KOiK00857.
OMAiFKGKPFG.
OrthoDBiPOG091H0659.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

F9YU51-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISKVFTNYI KNNKSLIYNT ILSLLVKNPS EIQKNTYFCE QYNSIMFLEN
60 70 80 90 100
TTNYSEKFGW IEVICGSMFS GKTEELIRRL RRAQFAKQKV EIFKPAFDTR
110 120 130 140 150
YDDVMVVSHN ANEIRSTPVP AAANIMLLAD GCDVIGIDEA QFFDDEIVTV
160 170 180 190 200
CNDLANRGMR VIVAGLDMDF KGKPFGPMPA LMATAEYVTK VHAVCTRTGN
210 220 230
LANFSYRKSA NENVFLLGEQ EAYEPLSRAA YFKAMKEKK
Length:239
Mass (Da):27,104
Last modified:October 19, 2011 - v1
Checksum:i7344888EC2AC8999
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002113 Genomic DNA. Translation: AEK24169.1.

Genome annotation databases

EnsemblBacteriaiAEK24169; AEK24169; Ccan_20530.
KEGGiccm:Ccan_20530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002113 Genomic DNA. Translation: AEK24169.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi860228.Ccan_20530.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAEK24169; AEK24169; Ccan_20530.
KEGGiccm:Ccan_20530.

Phylogenomic databases

eggNOGiENOG4107T8J. Bacteria.
COG1435. LUCA.
KOiK00857.
OMAiFKGKPFG.
OrthoDBiPOG091H0659.

Family and domain databases

HAMAPiMF_00124. Thymidine_kinase. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
[Graphical view]
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiPF00265. TK. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiF9YU51_CAPCC
AccessioniPrimary (citable) accession number: F9YU51
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: November 2, 2016
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.