ID   F9YS48_CAPCC            Unreviewed;       522 AA.
AC   F9YS48;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 59.
DE   SubName: Full=Neuraminidase {ECO:0000313|EMBL:AEK22601.1};
DE            EC=3.2.1.18 {ECO:0000313|EMBL:AEK22601.1};
GN   OrderedLocusNames=Ccan_04790 {ECO:0000313|EMBL:AEK22601.1};
OS   Capnocytophaga canimorsus (strain 5).
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Capnocytophaga.
OX   NCBI_TaxID=860228 {ECO:0000313|EMBL:AEK22601.1, ECO:0000313|Proteomes:UP000008895};
RN   [1] {ECO:0000313|EMBL:AEK22601.1, ECO:0000313|Proteomes:UP000008895}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5 {ECO:0000313|Proteomes:UP000008895};
RX   PubMed=21914877; DOI=10.1128/JB.05853-11;
RA   Manfredi P., Pagni M., Cornelis G.R.;
RT   "Complete genome sequence of the dog commensal and human pathogen
RT   Capnocytophaga canimorsus strain 5.";
RL   J. Bacteriol. 193:5558-5559(2011).
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DR   EMBL; CP002113; AEK22601.1; -; Genomic_DNA.
DR   RefSeq; WP_013996593.1; NC_015846.1.
DR   AlphaFoldDB; F9YS48; -.
DR   SMR; F9YS48; -.
DR   STRING; 860228.Ccan_04790; -.
DR   KEGG; ccm:Ccan_04790; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_024620_0_0_10; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000008895; Chromosome.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF19; SIALIDASE; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Glycosidase {ECO:0000313|EMBL:AEK22601.1};
KW   Hydrolase {ECO:0000313|EMBL:AEK22601.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008895};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..522
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003392025"
FT   DOMAIN          199..497
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   522 AA;  58538 MW;  1E3EC51A1B1E9ED9 CRC64;
     MNRIFYLLFA FVLLSACGSQ KNVIGGGEFT QPEMPLVTGK ENLLASFKLA TKNLNAITEV
     KVLLKSELKS LDLSEITIYL SDKENFKEAQ QFASTKSVQS TTLLKGNYLP KTENTYVWVT
     TKTTENPNLL NKIKVFQIEF LSNGSRYVYV NPKSASQRFG ITLRDKKQDG IECYRIPGLA
     TTNKGTLIAV YDNRYNNCKD LQEDVNVGMS RSTDGGQTWE PMKEIMDLGE WGGLDNRLNG
     IGDPAVLVDK TTGTIWVAAL WLHGHDKDKM AWWASKPGMT PHETGQLMLV KSEDDGITWS
     EPINITAQTK DPKWYLFFNG PGSGITLNDG KIMFAAQYKD ENQVPHSTLI YSDDHGKTWH
     CGTGAKSHTT EAQVVQLSDG SIMLNMRDDR NRQNYTLSDA FHGRSVAVTR DFGKTWTEHS
     TSRKALTEPN CMASIISLDK NGKKYLFFSN PADAKKRVNM TIKVSDDDGN TWDKLPALKL
     YENEGFGYSC MSIIDDKYIG ILYEGAGDLI FQKIPVEEFI KN
//