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F9Y470

- F9Y470_KETVW

UniProt

F9Y470 - F9Y470_KETVW

Protein

Acetyltransferase component of pyruvate dehydrogenase complex

Gene

pdhB

Organism
Ketogulonicigenium vulgare (strain WSH-001)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 18 (01 Oct 2014)
      Sequence version 1 (19 Oct 2011)
      Previous versions | rss
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    Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.UniRule annotation

    Catalytic activityi

    Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine.

    Cofactori

    Binds 1 lipoyl cofactor covalently.UniRule annotation
    Binds 2 lipoyl cofactors covalently.UniRule annotation
    Binds 3 lipoyl cofactors covalently.UniRule annotation

    GO - Molecular functioni

    1. dihydrolipoyllysine-residue acetyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pyruvate metabolic process Source: InterPro

    Keywords - Molecular functioni

    AcyltransferaseUniRule annotationImported, Transferase

    Keywords - Ligandi

    PyruvateImported

    Enzyme and pathway databases

    BioCyciKVUL759362:GLEX-694-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acetyltransferase component of pyruvate dehydrogenase complexUniRule annotation (EC:2.3.1.12UniRule annotation)
    Gene namesi
    Name:pdhBImported
    Ordered Locus Names:KVU_0667Imported
    OrganismiKetogulonicigenium vulgare (strain WSH-001)Imported
    Taxonomic identifieri759362 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeKetogulonicigenium
    ProteomesiUP000000692: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. pyruvate dehydrogenase complex Source: InterPro

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 lipoyl-binding domain.UniRule annotation

    Keywords - Domaini

    LipoylUniRule annotationSAAS annotation

    Phylogenomic databases

    KOiK00627.

    Family and domain databases

    Gene3Di3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProiIPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view]
    PfamiPF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view]
    SUPFAMiSSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsiTIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEiPS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F9Y470-1 [UniParc]FASTAAdd to Basket

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    MSIEILMPAL SPTMEEGTIA KWLVAEGDTV KSGDILAEIE TDKATMEFEA    50
    VDDGVIGKIL LPAGSEGVKV NTPMAILLED GETEAAAPKA AAPKVEAAPV 100
    EAPKAAPVAA AAAPVEKGDR VFASPLARRI AADKGLDLNA IAGSGPKGRI 150
    VRADVEGATA AKPAEAAKAP AAAAPTPAAP APVPTSSSAD QILKMYQGRD 200
    YTEVKLDGMR KTIAARLTEA KQTVPHFYLR RSVNLDALMA FRADLNAKLG 250
    PRGIKISVND FVIKACAIAL QQVPKANAIW AGDRVLQMKA SDVSIAVAVE 300
    GGLFTPVIRD ADAKSISALS AEMKDLAKRA RDKKLQPQDY QGGSFSISNL 350
    GMFGVENFDA VINPPQGAIL AVGAGIKKPI VGDDGEITTA TLMSLTLSVD 400
    HRVIDGALGA HLLTAIVENL ENPLSMLA 428
    Length:428
    Mass (Da):44,430
    Last modified:October 19, 2011 - v1
    Checksum:iDF28E1294E6FD9D5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002018 Genomic DNA. Translation: AEM40506.1.
    RefSeqiYP_005794502.1. NC_017384.1.

    Genome annotation databases

    EnsemblBacteriaiAEM40506; AEM40506; KVU_0667.
    GeneIDi12373522.
    KEGGikvl:KVU_0667.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP002018 Genomic DNA. Translation: AEM40506.1 .
    RefSeqi YP_005794502.1. NC_017384.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AEM40506 ; AEM40506 ; KVU_0667 .
    GeneIDi 12373522.
    KEGGi kvl:KVU_0667.

    Phylogenomic databases

    KOi K00627.

    Enzyme and pathway databases

    BioCyci KVUL759362:GLEX-694-MONOMER.

    Family and domain databases

    Gene3Di 3.30.559.10. 1 hit.
    4.10.320.10. 1 hit.
    InterProi IPR003016. 2-oxoA_DH_lipoyl-BS.
    IPR001078. 2-oxoacid_DH_actylTfrase.
    IPR000089. Biotin_lipoyl.
    IPR023213. CAT-like_dom.
    IPR004167. E3-bd.
    IPR006257. LAT1.
    IPR011053. Single_hybrid_motif.
    [Graphical view ]
    Pfami PF00198. 2-oxoacid_dh. 1 hit.
    PF00364. Biotin_lipoyl. 1 hit.
    PF02817. E3_binding. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47005. SSF47005. 1 hit.
    SSF51230. SSF51230. 1 hit.
    TIGRFAMsi TIGR01349. PDHac_trf_mito. 1 hit.
    PROSITEi PS50968. BIOTINYL_LIPOYL. 1 hit.
    PS00189. LIPOYL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the industrial strain Ketogulonicigenium vulgare WSH-001."
      Liu L., Li Y., Zhang J., Zhou Z., Liu J., Li X., Zhou J., Du G., Wang L., Chen J.
      J. Bacteriol. 193:6108-6109(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WSH-001Imported.

    Entry informationi

    Entry nameiF9Y470_KETVW
    AccessioniPrimary (citable) accession number: F9Y470
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 19, 2011
    Last sequence update: October 19, 2011
    Last modified: October 1, 2014
    This is version 18 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3