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F9Y470 (F9Y470_KETVW) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyltransferase component of pyruvate dehydrogenase complex RuleBase RU361137

EC=2.3.1.12 RuleBase RU361137
Gene names
Name:pdhB EMBL AEM40506.1
Ordered Locus Names:KVU_0667 EMBL AEM40506.1
OrganismKetogulonicigenium vulgare (strain WSH-001) [Complete proteome] [HAMAP] EMBL AEM40506.1
Taxonomic identifier759362 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeKetogulonicigenium

Protein attributes

Sequence length428 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2 By similarity. RuleBase RU361137

Catalytic activity

Acetyl-CoA + enzyme N(6)-(dihydrolipoyl)lysine = CoA + enzyme N(6)-(S-acetyldihydrolipoyl)lysine. RuleBase RU361137

Cofactor

Binds 1 lipoyl cofactor covalently By similarity. RuleBase RU361137

Binds 2 lipoyl cofactors covalently By similarity. RuleBase RU361137

Binds 3 lipoyl cofactors covalently By similarity. RuleBase RU361137

Sequence similarities

Belongs to the 2-oxoacid dehydrogenase family. RuleBase RU361137

Contains 1 lipoyl-binding domain. RuleBase RU361137

Sequences

Sequence LengthMass (Da)Tools
F9Y470 [UniParc].

Last modified October 19, 2011. Version 1.
Checksum: DF28E1294E6FD9D5

FASTA42844,430
        10         20         30         40         50         60 
MSIEILMPAL SPTMEEGTIA KWLVAEGDTV KSGDILAEIE TDKATMEFEA VDDGVIGKIL 

        70         80         90        100        110        120 
LPAGSEGVKV NTPMAILLED GETEAAAPKA AAPKVEAAPV EAPKAAPVAA AAAPVEKGDR 

       130        140        150        160        170        180 
VFASPLARRI AADKGLDLNA IAGSGPKGRI VRADVEGATA AKPAEAAKAP AAAAPTPAAP 

       190        200        210        220        230        240 
APVPTSSSAD QILKMYQGRD YTEVKLDGMR KTIAARLTEA KQTVPHFYLR RSVNLDALMA 

       250        260        270        280        290        300 
FRADLNAKLG PRGIKISVND FVIKACAIAL QQVPKANAIW AGDRVLQMKA SDVSIAVAVE 

       310        320        330        340        350        360 
GGLFTPVIRD ADAKSISALS AEMKDLAKRA RDKKLQPQDY QGGSFSISNL GMFGVENFDA 

       370        380        390        400        410        420 
VINPPQGAIL AVGAGIKKPI VGDDGEITTA TLMSLTLSVD HRVIDGALGA HLLTAIVENL 


ENPLSMLA 

« Hide

References

[1]"Complete genome sequence of the industrial strain Ketogulonicigenium vulgare WSH-001."
Liu L., Li Y., Zhang J., Zhou Z., Liu J., Li X., Zhou J., Du G., Wang L., Chen J.
J. Bacteriol. 193:6108-6109(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WSH-001 EMBL AEM40506.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP002018 Genomic DNA. Translation: AEM40506.1.
RefSeqYP_005794502.1. NC_017384.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAEM40506; AEM40506; KVU_0667.
GeneID12373522.
KEGGkvl:KVU_0667.

Organism-specific databases

CMRSearch...

Phylogenomic databases

KOK00627.

Enzyme and pathway databases

BioCycKVUL759362:GLEX-694-MONOMER.

Family and domain databases

Gene3D3.30.559.10. 1 hit.
4.10.320.10. 1 hit.
InterProIPR003016. 2-oxoA_DH_lipoyl-BS.
IPR001078. 2-oxoacid_DH_actylTfrase.
IPR000089. Biotin_lipoyl.
IPR023213. CAT-like_dom.
IPR004167. E3-bd.
IPR006257. LAT1.
IPR011053. Single_hybrid_motif.
[Graphical view]
PfamPF00198. 2-oxoacid_dh. 1 hit.
PF00364. Biotin_lipoyl. 1 hit.
PF02817. E3_binding. 1 hit.
[Graphical view]
SUPFAMSSF47005. SSF47005. 1 hit.
SSF51230. SSF51230. 1 hit.
TIGRFAMsTIGR01349. PDHac_trf_mito. 1 hit.
PROSITEPS50968. BIOTINYL_LIPOYL. 1 hit.
PS00189. LIPOYL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameF9Y470_KETVW
AccessionPrimary (citable) accession number: F9Y470
Entry history
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: July 9, 2014
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)