ID   F9X3S3_ZYMTI            Unreviewed;       482 AA.
AC   F9X3S3;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
DE   Flags: Fragment;
GN   Name=HKX2 {ECO:0000313|EMBL:EGP90492.1};
GN   ORFNames=MYCGRDRAFT_55383 {ECO:0000313|EMBL:EGP90492.1};
OS   Zymoseptoria tritici (strain CBS 115943 / IPO323) (Speckled leaf blotch
OS   fungus) (Septoria tritici).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Zymoseptoria.
OX   NCBI_TaxID=336722 {ECO:0000313|EMBL:EGP90492.1, ECO:0000313|Proteomes:UP000008062};
RN   [1] {ECO:0000313|EMBL:EGP90492.1, ECO:0000313|Proteomes:UP000008062}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 115943 / IPO323 {ECO:0000313|Proteomes:UP000008062};
RX   PubMed=21695235; DOI=10.1371/journal.pgen.1002070;
RA   Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F.,
RA   Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A.,
RA   Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A.,
RA   Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., Cools H.J.,
RA   Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B.,
RA   van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B.,
RA   Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A.,
RA   Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R.,
RA   Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J.,
RA   Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H.,
RA   de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H.,
RA   Oliver R.P., Grigoriev I.V., Kema G.H.J.;
RT   "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola
RT   reveals dispensome structure, chromosome plasticity, and stealth
RT   pathogenesis.";
RL   PLoS Genet. 7:E1002070-E1002070(2011).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|ARBA:ARBA00009225, ECO:0000256|RuleBase:RU362007}.
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DR   EMBL; CM001197; EGP90492.1; -; Genomic_DNA.
DR   RefSeq; XP_003855516.1; XM_003855468.1.
DR   AlphaFoldDB; F9X3S3; -.
DR   STRING; 336722.F9X3S3; -.
DR   EnsemblFungi; Mycgr3T55383; Mycgr3P55383; Mycgr3G55383.
DR   GeneID; 13403456; -.
DR   KEGG; ztr:MYCGRDRAFT_55383; -.
DR   eggNOG; KOG1369; Eukaryota.
DR   HOGENOM; CLU_014393_4_1_1; -.
DR   InParanoid; F9X3S3; -.
DR   OMA; FPVEQTS; -.
DR   OrthoDB; 5481886at2759; -.
DR   UniPathway; UPA00109; UER00180.
DR   Proteomes; UP000008062; Chromosome 2.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0001678; P:intracellular glucose homeostasis; IEA:InterPro.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.40.367.20; -; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; HEXOKINASE; 1.
DR   PANTHER; PTHR19443:SF24; HEXOKINASE YLR446W-RELATED; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PRINTS; PR00475; HEXOKINASE.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362007};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|RuleBase:RU362007};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU362007};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008062};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU362007}.
FT   DOMAIN          16..223
FT                   /note="Hexokinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00349"
FT   DOMAIN          229..481
FT                   /note="Hexokinase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03727"
FT   NON_TER         482
FT                   /evidence="ECO:0000313|EMBL:EGP90492.1"
SQ   SEQUENCE   482 AA;  53456 MW;  F1B4150CB439ED12 CRC64;
     MDEYLHNVRS QFEAPLHIDR LLEISKQLQQ ECRDRLQASD ISMLPSYQRS LPTGEERGDF
     LALDVGGSTF RIALIRLAGK TKAEHSSTCS ATHTPDTPCR SDSLQIRRIR TFTIDETVRR
     LRGEAFFDWM ADRIGDMLHE YNHIRGTSNA HLPMGLAWSF PIEQTSPHSG RLLAMGKGFL
     ATHGVENQDL SSLIMRSCRA KKLNVEMRAI VNDSAATLLA QSYRDSSVRM SLILGTGTNA
     AVYLPVSSLH PSKFGDRPES WFSDTTHVLV NTELSMLGKR SLPRTHWDDQ LNASHPLPDF
     QPLEYLITGR YLAEIFRLVL LEAEGSIVDF FSLPPAWRTT PYSVDASLLA IFEADTTPTL
     SLSRAAILPH YPPDSKTQIL APDLSFLRSI AQSITCRAST YLATALHALW VVRCEAEGLR
     PTTDQSRVSV ACAGSIVEKY PGYRQRAQRV LDELCGVGEC EEGYVRLGCS GESSVVGAAV
     AV
//