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Protein

DNA ligase

Gene

MYCGRDRAFT_68344

Organism
Mycosphaerella graminicola (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA biosynthetic process Source: InterPro
  2. DNA ligation involved in DNA repair Source: InterPro
  3. DNA recombination Source: UniProtKB-KW
  4. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotation

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:MYCGRDRAFT_68344Imported
OrganismiMycosphaerella graminicola (strain CBS 115943 / IPO323) (Speckled leaf blotch fungus) (Septoria tritici)Imported
Taxonomic identifieri336722 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesDothideomycetidaeCapnodialesMycosphaerellaceaeZymoseptoria
ProteomesiUP000008062: Chromosome 2

Structurei

3D structure databases

ProteinModelPortaliF9X2V5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP-dependent DNA ligase family.UniRule annotation

Phylogenomic databases

InParanoidiF9X2V5.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F9X2V5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYGHGSMTQD EMDEKYPGRP KNHAKTLPFH ELYTTLFNPL NENKKKPTGP
60 70 80 90 100
SIARKKEGPH GQGQAPHEAR RSIIDRFISR WRKQVGNDIF PAIRLIVPEK
110 120 130 140 150
DRERGMYGIK EMTLGKLLVR VMKINKDSED GYNLLHWKLP GVKASSAMAG
160 170 180 190 200
DFAGRCFEVI SKRPMRQTPG DMTIAQVNEM LDRLSVAQKE ENQRPIIEEF
210 220 230 240 250
YNRMCAEEMM WLIRMILRQM KVGASERTFF DVWHQDAENL FNISSNLRRV
260 270 280 290 300
CWELWDPDVR LEGDSAGIAL MQCFQPQLAA FQMRSMEQMV ARMKPTEEDA
310 320 330 340 350
EFWIEEKLDG ERMQLHMVED DQIPGGKRFG FWSRKAKDYT YLYGKHFEDD
360 370 380 390 400
NSALTRHIKN AFNEGVRNII LDGEMITWDP KEQALVPFGT LKTAALSEQQ
410 420 430 440 450
NPFSTGNRPV FRIFDCLFLN DKDLTHYTLR VRHEALLKSV TSIDQRMEIH
460 470 480 490 500
EHQKATQASE IEPVLRKVVA EASEGLVLKN PRSEYRLNER NDDWIKVKPE
510 520 530 540 550
YMTEFGESLD CIVVGGYYGS GKRGGGLSSF LCGLKPQQAI FSSQNRNINP
560 570 580 590 600
QMVLSFFKVG GGFAASDYAE IRHRTEGKWT DWNAKKPPTD WVVLGGGDRQ
610 620 630 640 650
FEKPDVWIKP EDSIVLSVKA ASVTGTTQFA TGCTLRFPRF KKLRTDKDWT
660 670 680 690 700
QALTQDEFNA LRKRVEAEVE EKKMKIDDTR KQKVGPKRKK RELVIQGQED
710 720 730 740 750
AVRAPYAGPA TKVFEGLSFF VMTEAPKPLK KTKAELEQLI KANGGNVVAS
760 770 780 790 800
EKDPDTIIIA DRNMVKVASI SKHDKRSIIR PSWLLDCVRQ SEIDIGRPAL
810 820 830 840 850
LLPLEKFHLF HTASAEQGRF DDNVDEYGDS YARDITTEEL LALCNAMPSK
860 870 880 890 900
MEDGLNPDEV LEQFHDHGHE LDAMKGFMFR GTTAYFDDVP AEAIRLFKFA
910 920 930 940 950
GGQIADSIED DQLTHVVLHT GCSPAATRKA VSSKQQLPRI VTESWVADSW
960
SEATRLDEEQ FVPS
Length:964
Mass (Da):110,023
Last modified:October 19, 2011 - v1
Checksum:iC1CE5B7451D732CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM001197 Genomic DNA. Translation: EGP90536.1.
RefSeqiXP_003855560.1. XM_003855512.1.

Genome annotation databases

EnsemblFungiiMycgr3T68344; Mycgr3P68344; Mycgr3G68344.
GeneIDi13399568.
KEGGiztr:MYCGRDRAFT_68344.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM001197 Genomic DNA. Translation: EGP90536.1.
RefSeqiXP_003855560.1. XM_003855512.1.

3D structure databases

ProteinModelPortaliF9X2V5.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiMycgr3T68344; Mycgr3P68344; Mycgr3G68344.
GeneIDi13399568.
KEGGiztr:MYCGRDRAFT_68344.

Phylogenomic databases

InParanoidiF9X2V5.
KOiK10777.
OrthoDBiEOG7QC84G.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR029710. LIG4.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PANTHERiPTHR10459:SF7. PTHR10459:SF7. 1 hit.
PfamiPF00533. BRCT. 1 hit.
PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Finished genome of the fungal wheat pathogen Mycosphaerella graminicola reveals dispensome structure, chromosome plasticity, and stealth pathogenesis."
    Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., Crane C.F., Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., Aerts A., Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., van der Burgt A., Canto-Canche B., Churchill A.C.L.
    , Conde-Ferraez L., Cools H.J., Coutinho P.M., Csukai M., Dehal P., De Wit P., Donzelli B., van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., Henrissat B., Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., Kuzniar A., Lindquist E., Lombard V., Maliepaard C., Martins N., Mehrabi R., Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., Schmutz J., Schouten H.J., Shapiro H., Stergiopoulos I., Torriani S.F.F., Tu H., de Vries R.P., Waalwijk C., Ware S.B., Wiebenga A., Zwiers L.-H., Oliver R.P., Grigoriev I.V., Kema G.H.J.
    PLoS Genet. 7:E1002070-E1002070(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CBS 115943 / IPO323Imported.

Entry informationi

Entry nameiF9X2V5_MYCGM
AccessioniPrimary (citable) accession number: F9X2V5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: February 4, 2015
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.