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Protein
Submitted name:

Putative 4-aminobutyrate aminotransferase

Gene

gabT

Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei281 – 2811N6-(pyridoxalphosphate)lysine (covalent)Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-829-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative 4-aminobutyrate aminotransferaseImported (EC:2.6.1.19Imported)
Gene namesi
Name:gabTImported
Ordered Locus Names:STK_07350Imported
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)Imported
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001015 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi273063.ST0735.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EO5X-ray1.90A1-419[»]
ProteinModelPortaliF9VN77.
SMRiF9VN77. Positions 1-418.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

KOiK00823.
OMAiNLCAEAN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProiIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F9VN77-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSRKIIEES DIYLATSTRD PELFPLVIDH GEGVWIYDVD GNKYLDFTSG
60 70 80 90 100
IGVNNLGWPS HPEVIKIGIE QMQKLAHAAA NDFYNIPQLE LAKKLVTYSP
110 120 130 140 150
GNFQKKVFFS NSGTEAIEAS IKVVKNTGRK YIIAFLGGFH GRTFGSISLT
160 170 180 190 200
ASKAVQRSIV GPFMPGVIHV PYPNPYRNPW HINGYENPSE LVNRVIEFIE
210 220 230 240 250
DYIFVNLVPP EEVAGIFFEP IQGEGGYVIP PKNFFAELQK LAKKYGILLV
260 270 280 290 300
DDEVQMGLGR TGKLFAIENF NTVPDVITLA KALGGGIMPI GATIFRKDLD
310 320 330 340 350
FKPGMHSNTF GGNALACAIG SKVIDIVKDL LPHVNEIGKI FAEELQGLAD
360 370 380 390 400
DVRGIGLAWG LEYNEKKVRD RIIGESFKRG LLLLPAGRSA IRVIPPLVIS
410
EEEAKQGLDI LKKVIKVVK
Length:419
Mass (Da):46,218
Last modified:October 19, 2011 - v1
Checksum:i8E356A3B12F7E83F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAK54374.1.
RefSeqiNP_376633.1. NC_003106.2.
WP_010978725.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAK54374; BAK54374; STK_07350.
GeneIDi1458692.
KEGGisto:ST0735.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAK54374.1.
RefSeqiNP_376633.1. NC_003106.2.
WP_010978725.1. NC_003106.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2EO5X-ray1.90A1-419[»]
ProteinModelPortaliF9VN77.
SMRiF9VN77. Positions 1-418.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273063.ST0735.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAK54374; BAK54374; STK_07350.
GeneIDi1458692.
KEGGisto:ST0735.

Phylogenomic databases

KOiK00823.
OMAiNLCAEAN.

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-829-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProiIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7Imported.
  2. "Crystal structure of 4-aminobutyrate aminotransferase from Sulfolobus tokodaii strain7."
    Mizutani H., Kunishima N.
    Submitted (MAR-2007) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS) IN COMPLEX WITH N6-(PYRIDOXALPHOSPHATE)LYSINE.

Entry informationi

Entry nameiF9VN77_SULTO
AccessioniPrimary (citable) accession number: F9VN77
Entry historyi
Integrated into UniProtKB/TrEMBL: October 19, 2011
Last sequence update: October 19, 2011
Last modified: June 24, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.