ID   F9D229_PREDD            Unreviewed;       456 AA.
AC   F9D229;
DT   19-OCT-2011, integrated into UniProtKB/TrEMBL.
DT   19-OCT-2011, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE            EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN   OrderedLocusNames=Prede_1036 {ECO:0000313|EMBL:AGB28373.1};
GN   ORFNames=HMPREF9136_0907 {ECO:0000313|EMBL:EGQ15847.1};
OS   Prevotella dentalis (strain ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043
OS   / ES 2772) (Mitsuokella dentalis).
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC   Prevotella.
OX   NCBI_TaxID=908937 {ECO:0000313|EMBL:EGQ15847.1, ECO:0000313|Proteomes:UP000007820};
RN   [1] {ECO:0000313|EMBL:EGQ15847.1, ECO:0000313|Proteomes:UP000007820}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 3688 {ECO:0000313|EMBL:EGQ15847.1,
RC   ECO:0000313|Proteomes:UP000007820};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000010862}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49559 / DSM 3688 / JCM 13448 / NCTC 12043 / ES 2772
RC   {ECO:0000313|Proteomes:UP000010862};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA   Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA   Eisen J.A.;
RT   "Complete sequence of chromosome 1 of Prevotella dentalis DSM 3688.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AGB28373.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=DSM 3688 {ECO:0000313|EMBL:AGB28373.1};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Peters L., Mikhailova N., Chertkov O.,
RA   Kyrpides N., Mavromatis K., Ivanova N., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA   Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E., Klenk H.-P.,
RA   Eisen J.A.;
RT   "Complete sequence of chromosome 1 of Prevotella dentalis DSM 3688.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP003368; AGB28373.1; -; Genomic_DNA.
DR   EMBL; AFPW01000012; EGQ15847.1; -; Genomic_DNA.
DR   RefSeq; WP_005844769.1; NZ_GL982488.1.
DR   AlphaFoldDB; F9D229; -.
DR   STRING; 908937.Prede_1036; -.
DR   KEGG; pdt:Prede_1036; -.
DR   PATRIC; fig|908937.9.peg.1085; -.
DR   eggNOG; COG4409; Bacteria.
DR   HOGENOM; CLU_025267_1_0_10; -.
DR   OrthoDB; 7294637at2; -.
DR   Proteomes; UP000007820; Unassembled WGS sequence.
DR   Proteomes; UP000010862; Chromosome 1.
DR   GO; GO:0004308; F:exo-alpha-sialidase activity; IEA:InterPro.
DR   CDD; cd15482; Sialidase_non-viral; 1.
DR   Gene3D; 2.120.10.10; -; 1.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; SIALIDASE; 1.
DR   PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   SUPFAM; SSF50939; Sialidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000010862};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          106..358
FT                   /note="Sialidase"
FT                   /evidence="ECO:0000259|Pfam:PF13088"
SQ   SEQUENCE   456 AA;  50868 MW;  07577AD870CDDCA6 CRC64;
     MKNSIPLSQM LMRNNFCRRI KGLRVTPVQL AFVLLVGFPI GTTAQTTDKE VVVFDNVHSE
     VPYRIPALAY TRDGRLIAVC DYRISKSDIG INNRNGLWQI NEVMRMSTDN GRTWGAVKTV
     AEGNELADDW HAAFGDPCIV ADRESDQILM GCVAGKIGYW GENRSTRGRR QDCVFFRSND
     GGHTWGPGEL RTDDIWNLYE GTLPGGQSAH GLFLTSGKIM QSRYVKAGSH YRLYIAHPVR
     LDSFDKRMGT FVIYSDDFGK TWRVLGGTAA PASIAQDESK VEELPDGSVL LSCRDKDGGR
     RFNVYTYTDP KTAAGTWGEE VMPSNMTRDS INAVNGGIMV VSARQTSTGR PICLLLQSVP
     QSPERRTMGF YYKVVTNRTD YATPSRLAAG WVKGLKITDA TACYSTMVLM DDGYIGLLYE
     KNSHNDGYDI VFQRLSLDEI TGNQYHYDDT QPCRPT
//