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Protein
Submitted name:

Calcium/calmodulin-dependent protein kinase type II subunit alpha

Gene

Camk2a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium/calmodulin-dependent protein kinase type II subunit alphaImported
Gene namesi
Name:Camk2aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:88256. Camk2a.

PTM / Processingi

Proteomic databases

MaxQBiF8WIS9.
PaxDbiF8WIS9.
PeptideAtlasiF8WIS9.
PRIDEiF8WIS9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000024617.
ExpressionAtlasiF8WIS9. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiF8WIS9. 1 interactor.
STRINGi10090.ENSMUSP00000099952.

Structurei

3D structure databases

ProteinModelPortaliF8WIS9.
SMRiF8WIS9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 271Protein kinaseInterPro annotationAdd BLAST259

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0033. Eukaryota.
ENOG410XNRX. LUCA.
GeneTreeiENSGT00760000118944.
OMAiVTQYIDA.
OrthoDBiEOG091G0SCS.

Family and domain databases

Gene3Di3.10.450.50. 1 hit.
InterProiIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543. Ca/CaM-dep_prot_kinase-assoc.
IPR011009. Kinase-like_dom.
IPR032710. NTF2-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR24347. PTHR24347. 1 hit.
PfamiPF08332. CaMKII_AD. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF54427. SSF54427. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8WIS9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATITCTRFT EEYQLFEELG KGAFSVVRRC VKVLAGQEYA AKIINTKKLS
60 70 80 90 100
ARDHQKLERE ARICRLLKHP NIVRLHDSIS EEGHHYLIFD LVTGGELFED
110 120 130 140 150
IVAREYYSEA DASHCIQQIL EAVLHCHQMG VVHRDLKPEN LLLASKLKGA
160 170 180 190 200
AVKLADFGLA IEVEGEQQAW FGFAGTPGYL SPEVLRKDPY GKPVDLWACG
210 220 230 240 250
VILYILLVGY PPFWDEDQHR LYQQIKAGAY DFPSPEWDTV TPEAKDLINK
260 270 280 290 300
MLTINPSKRI TAAEALKHPW ISHRSTVASC MHRQETVDCL KKFNARRKLK
310 320 330 340 350
GAILTTMLAT RNFSGGKSGG NKKNDGVKKR KSSSSVQLME SSESTNTTIE
360 370 380 390 400
DEDTKVRKQE IIKVTEQLIE AISNGDFESY TKMCDPGMTA FEPEALGNLV
410 420 430 440 450
EGLDFHRFYF ENLWSRNSKP VHTTILNPHI HLMGDESACI AYIRITQYLD
460 470 480
AGGIPRTAQS EETRVWHRRD GKWQIVHFHR SGAPSVLPH
Length:489
Mass (Da):55,347
Last modified:September 21, 2011 - v1
Checksum:iABFEC3059FC8C91D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124431 Genomic DNA. No translation available.
RefSeqiXP_006525604.1. XM_006525541.3.
UniGeneiMm.131530.
Mm.446530.

Genome annotation databases

EnsembliENSMUST00000025519; ENSMUSP00000025519; ENSMUSG00000024617.
GeneIDi12322.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124431 Genomic DNA. No translation available.
RefSeqiXP_006525604.1. XM_006525541.3.
UniGeneiMm.131530.
Mm.446530.

3D structure databases

ProteinModelPortaliF8WIS9.
SMRiF8WIS9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiF8WIS9. 1 interactor.
STRINGi10090.ENSMUSP00000099952.

Proteomic databases

MaxQBiF8WIS9.
PaxDbiF8WIS9.
PeptideAtlasiF8WIS9.
PRIDEiF8WIS9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025519; ENSMUSP00000025519; ENSMUSG00000024617.
GeneIDi12322.

Organism-specific databases

CTDi815.
MGIiMGI:88256. Camk2a.

Phylogenomic databases

eggNOGiKOG0033. Eukaryota.
ENOG410XNRX. LUCA.
GeneTreeiENSGT00760000118944.
OMAiVTQYIDA.
OrthoDBiEOG091G0SCS.

Miscellaneous databases

ChiTaRSiCamk2a. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000024617.
ExpressionAtlasiF8WIS9. baseline and differential.

Family and domain databases

Gene3Di3.10.450.50. 1 hit.
InterProiIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543. Ca/CaM-dep_prot_kinase-assoc.
IPR011009. Kinase-like_dom.
IPR032710. NTF2-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PANTHERiPTHR24347. PTHR24347. 1 hit.
PfamiPF08332. CaMKII_AD. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF54427. SSF54427. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF8WIS9_MOUSE
AccessioniPrimary (citable) accession number: F8WIS9
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 30, 2016
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.