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Protein
Submitted name:

E3 SUMO-protein ligase PIAS2

Gene

Pias2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri324 – 401SP-RING-typePROSITE-ProRule annotationAdd BLAST78

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
E3 SUMO-protein ligase PIAS2Imported
Gene namesi
Name:Pias2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1096566 Pias2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiF8WHS8
PeptideAtlasiF8WHS8
PRIDEiF8WHS8

Expressioni

Gene expression databases

BgeeiENSMUSG00000025423
ExpressionAtlasiF8WHS8 baseline and differential
GenevisibleiF8WHS8 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF8WHS8
SMRiF8WHS8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 38SAPInterPro annotationAdd BLAST35
Domaini127 – 292PINITInterPro annotationAdd BLAST166
Domaini324 – 401SP-RING-typeInterPro annotationAdd BLAST78

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri324 – 401SP-RING-typePROSITE-ProRule annotationAdd BLAST78

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG2169 Eukaryota
ENOG410XQ2E LUCA
GeneTreeiENSGT00550000074410

Family and domain databases

Gene3Di1.10.720.30, 1 hit
2.60.120.780, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR027228 PIAS2
IPR023321 PINIT
IPR038654 PINIT_sf
IPR003034 SAP_dom
IPR036361 SAP_dom_sf
IPR004181 Znf_MIZ
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR10782:SF12 PTHR10782:SF12, 1 hit
PfamiView protein in Pfam
PF14324 PINIT, 1 hit
PF02891 zf-MIZ, 1 hit
SMARTiView protein in SMART
SM00513 SAP, 1 hit
SUPFAMiSSF68906 SSF68906, 1 hit
PROSITEiView protein in PROSITE
PS51466 PINIT, 1 hit
PS50800 SAP, 1 hit
PS51044 ZF_SP_RING, 1 hit

Sequencei

Sequence statusi: Complete.

F8WHS8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMVSSFRVS ELQVLLGFAG RNKSGRKHDL LMRALHLLKS GCSPAVQIKI
60 70 80 90 100
RELYRRRYPR TLEGLCDLST IKSSVFSLDG SSSPVEPDLP VAGIHSLPST
110 120 130 140 150
SITPHSPSSP VGSVLLQDTK PTFEMQQPSP PIPPVHPDVQ LKNLPFYDVL
160 170 180 190 200
DVLIKPTSLV QSSIQRFQEK FFIFALTPQQ VREICISRDF LPGGRRDYTV
210 220 230 240 250
QVQLRLCLAE TSCPQEDNYP NSLCIKVNGK LFPLPGYAPP PKNGIEQKRP
260 270 280 290 300
GRPLNITSLV RLSSAVPNQI SISWASEIGK NYSMSVYLVR QLTSAMLLQR
310 320 330 340 350
LKMKGIRNPD HSRALIKEKL TADPDSEIAT TSLRVSLMCP LGKMRLTIPC
360 370 380 390 400
RAVTCTHLQC FDAALYLQMN EKKPTWICPV CDKKAAYESL ILDGLFMEIL
410 420 430 440 450
NDCSDVDEIK FQEDGSWCPM RPKKEAMKVT SQPCTKVESS SVFSKPCSVT
460 470 480 490 500
VASDASKKKI DVIDLTIESS SDEEEDPPAK RKCIFMSETQ SSPTKGVLMY
510 520 530 540 550
QPSSVRVPSV TSVDPAAIPP SLTDYSVPFH HTPVSSMSSD LPGEQRRNDI
560
NNEVQLGASS DTVQQ
Length:565
Mass (Da):62,597
Last modified:September 21, 2011 - v1
Checksum:i5AE07B23AFBA7C1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC132608 Genomic DNA No translation available.
AC157991 Genomic DNA No translation available.
RefSeqiNP_001157642.1, NM_001164170.1
UniGeneiMm.6370

Genome annotation databases

EnsembliENSMUST00000114776; ENSMUSP00000110424; ENSMUSG00000025423
GeneIDi17344
UCSCiuc008frd.2 mouse

Similar proteinsi

Entry informationi

Entry nameiF8WHS8_MOUSE
AccessioniPrimary (citable) accession number: F8WHS8
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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