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Protein
Submitted name:

Calcium/calmodulin-dependent protein kinase type II subunit alpha

Gene

Camk2a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium/calmodulin-dependent protein kinase type II subunit alphaImported
Gene namesi
Name:Camk2aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:88256. Camk2a.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence analysisAdd
BLAST
Chaini28 – 189162Sequence analysisPRO_5003379505Add
BLAST

Proteomic databases

PaxDbiF8WHB5.

Expressioni

Gene expression databases

BgeeiF8WHB5.
ExpressionAtlasiF8WHB5. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099952.

Structurei

3D structure databases

ProteinModelPortaliF8WHB5.
SMRiF8WHB5. Positions 47-185.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 184128CaMKII_ADInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0033. Eukaryota.
ENOG410XNRX. LUCA.
GeneTreeiENSGT00760000118944.
KOiK04515.

Family and domain databases

Gene3Di3.10.450.50. 1 hit.
InterProiIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543. Ca/CaM-dep_prot_kinase-assoc.
IPR032710. NTF2-like_dom.
[Graphical view]
PANTHERiPTHR24347. PTHR24347. 1 hit.
PfamiPF08332. CaMKII_AD. 1 hit.
[Graphical view]
SUPFAMiSSF54427. SSF54427. 1 hit.

Sequencei

Sequence statusi: Complete.

F8WHB5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLFLTLWAL VPCLVLLTLY FLSSTGGKSG GNKKNDGVKE SSESTNTTIE
60 70 80 90 100
DEDTKVRKQE IIKVTEQLIE AISNGDFESY TKMCDPGMTA FEPEALGNLV
110 120 130 140 150
EGLDFHRFYF ENLWSRNSKP VHTTILNPHI HLMGDESACI AYIRITQYLD
160 170 180
AGGIPRTAQS EETRVWHRRD GKWQIVHFHR SGAPSVLPH
Length:189
Mass (Da):21,351
Last modified:September 21, 2011 - v1
Checksum:i0C7607B4B01BA49C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124431 Genomic DNA. No translation available.
RefSeqiNP_001273738.1. NM_001286809.1.
UniGeneiMm.131530.
Mm.446530.

Genome annotation databases

EnsembliENSMUST00000039904; ENSMUSP00000048325; ENSMUSG00000024617.
GeneIDi12322.
KEGGimmu:12322.
UCSCiuc033hhl.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124431 Genomic DNA. No translation available.
RefSeqiNP_001273738.1. NM_001286809.1.
UniGeneiMm.131530.
Mm.446530.

3D structure databases

ProteinModelPortaliF8WHB5.
SMRiF8WHB5. Positions 47-185.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099952.

Proteomic databases

PaxDbiF8WHB5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000039904; ENSMUSP00000048325; ENSMUSG00000024617.
GeneIDi12322.
KEGGimmu:12322.
UCSCiuc033hhl.1. mouse.

Organism-specific databases

CTDi815.
MGIiMGI:88256. Camk2a.

Phylogenomic databases

eggNOGiKOG0033. Eukaryota.
ENOG410XNRX. LUCA.
GeneTreeiENSGT00760000118944.
KOiK04515.

Miscellaneous databases

ChiTaRSiCamk2a. mouse.
SOURCEiSearch...

Gene expression databases

BgeeiF8WHB5.
ExpressionAtlasiF8WHB5. baseline and differential.

Family and domain databases

Gene3Di3.10.450.50. 1 hit.
InterProiIPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase.
IPR013543. Ca/CaM-dep_prot_kinase-assoc.
IPR032710. NTF2-like_dom.
[Graphical view]
PANTHERiPTHR24347. PTHR24347. 1 hit.
PfamiPF08332. CaMKII_AD. 1 hit.
[Graphical view]
SUPFAMiSSF54427. SSF54427. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
    Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
    Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF8WHB5_MOUSE
AccessioniPrimary (citable) accession number: F8WHB5
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 8, 2016
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.