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Protein
Submitted name:

Leukemia inhibitory factor

Gene

Lif

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Leukemia inhibitory factorImported
Gene namesi
Name:LifImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:96787. Lif.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiF8WH42.

Expressioni

Gene expression databases

BgeeiF8WH42.
ExpressionAtlasiF8WH42. baseline and differential.
GenevisibleiF8WH42. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000067066.

Structurei

3D structure databases

ProteinModelPortaliF8WH42.
SMRiF8WH42. Positions 1-158.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410ITBQ. Eukaryota.
ENOG410YVPP. LUCA.
GeneTreeiENSGT00390000000059.
KOiK05419.

Family and domain databases

Gene3Di1.20.1250.10. 1 hit.
InterProiIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR003624. Leukemia_IF.
IPR001581. Leukemia_IF/oncostatin.
IPR019827. Leukemia_IF/oncostatin_CS.
[Graphical view]
PANTHERiPTHR10633. PTHR10633. 1 hit.
PfamiPF01291. LIF_OSM. 1 hit.
[Graphical view]
PRINTSiPR01883. LEUKAEMIAIF.
SMARTiSM00080. LIF_OSM. 1 hit.
[Graphical view]
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiPS00590. LIF_OSM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8WH42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQIKNQLAQ LNGSANALFI SYYTAQGEPF PNNVEKLCAP NMTDFPSFHG
60 70 80 90 100
NGTEKTKLVE LYRMVAYLSA SLTNITRDQK VLNPTAVSLQ VKLNATIDVM
110 120 130 140 150
RGLLSNVLCR LCNKYRVGHV DVPPVPDHSD KEAFQRKKLG CQLLGTYKQV

ISVVVQAF
Length:158
Mass (Da):17,574
Last modified:September 21, 2011 - v1
Checksum:iDD867142A62F322E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL731658 Genomic DNA. No translation available.
RefSeqiNP_001034626.1. NM_001039537.2.
XP_006514607.1. XM_006514544.2.
UniGeneiMm.4964.

Genome annotation databases

EnsembliENSMUST00000040750; ENSMUSP00000036853; ENSMUSG00000034394.
GeneIDi16878.
KEGGimmu:16878.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL731658 Genomic DNA. No translation available.
RefSeqiNP_001034626.1. NM_001039537.2.
XP_006514607.1. XM_006514544.2.
UniGeneiMm.4964.

3D structure databases

ProteinModelPortaliF8WH42.
SMRiF8WH42. Positions 1-158.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000067066.

Proteomic databases

PaxDbiF8WH42.

Protocols and materials databases

DNASUi16878.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000040750; ENSMUSP00000036853; ENSMUSG00000034394.
GeneIDi16878.
KEGGimmu:16878.

Organism-specific databases

CTDi3976.
MGIiMGI:96787. Lif.

Phylogenomic databases

eggNOGiENOG410ITBQ. Eukaryota.
ENOG410YVPP. LUCA.
GeneTreeiENSGT00390000000059.
KOiK05419.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiF8WH42.
ExpressionAtlasiF8WH42. baseline and differential.
GenevisibleiF8WH42. MM.

Family and domain databases

Gene3Di1.20.1250.10. 1 hit.
InterProiIPR009079. 4_helix_cytokine-like_core.
IPR012351. 4_helix_cytokine_core.
IPR003624. Leukemia_IF.
IPR001581. Leukemia_IF/oncostatin.
IPR019827. Leukemia_IF/oncostatin_CS.
[Graphical view]
PANTHERiPTHR10633. PTHR10633. 1 hit.
PfamiPF01291. LIF_OSM. 1 hit.
[Graphical view]
PRINTSiPR01883. LEUKAEMIAIF.
SMARTiSM00080. LIF_OSM. 1 hit.
[Graphical view]
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiPS00590. LIF_OSM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiF8WH42_MOUSE
AccessioniPrimary (citable) accession number: F8WH42
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 8, 2016
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.