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Protein
Submitted name:

Leukemia inhibitory factor

Gene

Lif

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Leukemia inhibitory factorImported
Gene namesi
Name:LifImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:96787. Lif.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF8WH42.
PRIDEiF8WH42.

Expressioni

Gene expression databases

BgeeiENSMUSG00000034394.
ExpressionAtlasiF8WH42. baseline and differential.
GenevisibleiF8WH42. MM.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF8WH42.
SMRiF8WH42.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410ITBQ. Eukaryota.
ENOG410YVPP. LUCA.
GeneTreeiENSGT00390000000059.

Family and domain databases

InterProiView protein in InterPro
IPR009079. 4_helix_cytokine-like_core.
IPR003624. Leukemia_IF.
IPR001581. Leukemia_IF/oncostatin.
IPR019827. Leukemia_IF/oncostatin_CS.
PANTHERiPTHR10633. PTHR10633. 1 hit.
PfamiView protein in Pfam
PF01291. LIF_OSM. 1 hit.
PRINTSiPR01883. LEUKAEMIAIF.
SMARTiView protein in SMART
SM00080. LIF_OSM. 1 hit.
SUPFAMiSSF47266. SSF47266. 1 hit.
PROSITEiView protein in PROSITE
PS00590. LIF_OSM. 1 hit.

Sequencei

Sequence statusi: Complete.

F8WH42-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQIKNQLAQ LNGSANALFI SYYTAQGEPF PNNVEKLCAP NMTDFPSFHG
60 70 80 90 100
NGTEKTKLVE LYRMVAYLSA SLTNITRDQK VLNPTAVSLQ VKLNATIDVM
110 120 130 140 150
RGLLSNVLCR LCNKYRVGHV DVPPVPDHSD KEAFQRKKLG CQLLGTYKQV

ISVVVQAF
Length:158
Mass (Da):17,574
Last modified:September 21, 2011 - v1
Checksum:iDD867142A62F322E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL731658 Genomic DNA. No translation available.
RefSeqiNP_001034626.1. NM_001039537.2.
XP_006514607.1. XM_006514544.3.
UniGeneiMm.4964.

Genome annotation databases

EnsembliENSMUST00000040750; ENSMUSP00000036853; ENSMUSG00000034394.
GeneIDi16878.

Similar proteinsi

Entry informationi

Entry nameiF8WH42_MOUSE
AccessioniPrimary (citable) accession number: F8WH42
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: August 30, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported