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Protein
Submitted name:

Cofilin-1

Gene

Cfl1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cofilin-1Imported
Gene namesi
Name:Cfl1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:101757. Cfl1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiF8WGL3.
PaxDbiF8WGL3.
PeptideAtlasiF8WGL3.
PRIDEiF8WGL3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000056201.
ExpressionAtlasiF8WGL3. baseline and differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF8WGL3.
SMRiF8WGL3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 153ADF-HInterPro annotationAdd BLAST150

Sequence similaritiesi

Belongs to the actin-binding proteins ADF family.SAAS annotation

Phylogenomic databases

eggNOGiKOG1735. Eukaryota.
ENOG41122P5. LUCA.
GeneTreeiENSGT00440000033289.
OMAiPTFVIYR.
OrthoDBiEOG091G0PWC.
TreeFamiTF328601.

Family and domain databases

CDDicd11286. ADF_cofilin_like. 1 hit.
Gene3Di3.40.20.10. 1 hit.
InterProiView protein in InterPro
IPR002108. ADF-H.
IPR029006. ADF-H/Gelsolin-like_dom_sf.
IPR017904. ADF/Cofilin.
IPR027234. Cofilin_1.
PANTHERiPTHR11913. PTHR11913. 1 hit.
PTHR11913:SF17. PTHR11913:SF17. 1 hit.
PfamiView protein in Pfam
PF00241. Cofilin_ADF. 1 hit.
PRINTSiPR00006. COFILIN.
SMARTiView protein in SMART
SM00102. ADF. 1 hit.
PROSITEiView protein in PROSITE
PS51263. ADF_H. 1 hit.

Sequencei

Sequence statusi: Complete.

F8WGL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE
60 70 80 90 100
EGKEILVGDV GQTVDDPYTT FVKMLPDKDC RYALYDATYE TKESKKEDLV
110 120 130 140 150
FIFWAPENAP LKSKMIYASS KDAIKKKLTG IKHELQANCY EEVKDRCTLA
160 170 180 190 200
EKLGGSAVIS LEGKPLSHPA PCLEHLNSPR PALGCCRLPL SCQTGGAGGI
210 220
PAGGGLSLHP SCQTSLPPPG PSFSLHP
Length:227
Mass (Da):24,576
Last modified:September 21, 2011 - v1
Checksum:i2B7C3A4FD13F9830
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC126029 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000116560; ENSMUSP00000112259; ENSMUSG00000056201.

Similar proteinsi

Entry informationi

Entry nameiF8WGL3_MOUSE
AccessioniPrimary (citable) accession number: F8WGL3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 22, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported