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F8WGL3 (F8WGL3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Protein attributes

Sequence length227 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains ADF-H domain. SAAS SAAS002108

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000112259

Ontologies

Keywords
   LigandActin-binding SAAS SAAS017904
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processactin filament depolymerization

Inferred from electronic annotation. Source: InterPro

actin filament organization

Inferred from mutant phenotype PubMed 15606898. Source: MGI

cell projection organization

Inferred from sequence orthology PubMed 16286931. Source: MGI

cellular component movement

Inferred from mutant phenotype PubMed 15548599. Source: MGI

establishment of cell polarity

Inferred from mutant phenotype PubMed 15606898. Source: MGI

mitotic cytokinesis

Inferred from mutant phenotype PubMed 15548599. Source: MGI

negative regulation of cell size

Inferred from sequence orthology PubMed 16286931. Source: MGI

neural crest cell migration

Inferred from mutant phenotype PubMed 15649475. Source: MGI

neural fold formation

Inferred from mutant phenotype PubMed 15649475. Source: MGI

positive regulation of actin filament depolymerization

Inferred from mutant phenotype PubMed 15548599. Source: MGI

protein import into nucleus

Inferred from electronic annotation. Source: Ensembl

protein phosphorylation

Inferred from direct assay PubMed 17018287. Source: MGI

regulation of cell morphogenesis

Inferred from electronic annotation. Source: Ensembl

response to amino acid

Inferred from direct assay PubMed 17018287. Source: MGI

response to virus

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentcell-cell junction

Inferred from direct assay PubMed 23793062. Source: MGI

cortical actin cytoskeleton

Inferred from direct assay PubMed 15004221PubMed 15548599. Source: MGI

cytoplasm

Inferred from direct assay PubMed 15548599. Source: MGI

lamellipodium

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
F8WGL3 [UniParc].

Last modified September 21, 2011. Version 1.
Checksum: 2B7C3A4FD13F9830

FASTA22724,576
        10         20         30         40         50         60 
MASGVAVSDG VIKVFNDMKV RKSSTPEEVK KRKKAVLFCL SEDKKNIILE EGKEILVGDV 

        70         80         90        100        110        120 
GQTVDDPYTT FVKMLPDKDC RYALYDATYE TKESKKEDLV FIFWAPENAP LKSKMIYASS 

       130        140        150        160        170        180 
KDAIKKKLTG IKHELQANCY EEVKDRCTLA EKLGGSAVIS LEGKPLSHPA PCLEHLNSPR 

       190        200        210        220 
PALGCCRLPL SCQTGGAGGI PAGGGLSLHP SCQTSLPPPG PSFSLHP 

« Hide

References

« Hide 'large scale' references
[1]"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.M., Polakiewicz R.D., Comb M.J.
Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[2]"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[3]"Quantitative time-resolved phosphoproteomic analysis of mast cell signaling."
Cao L., Yu K., Banh C., Nguyen V., Ritz A., Raphael B.J., Kawakami Y., Kawakami T., Salomon A.R.
J. Immunol. 179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[4]"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[5]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000112259.
[6]Ensembl
Submitted (JUL-2011) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000112259.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC126029 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortalF8WGL3.
SMRF8WGL3. Positions 1-166.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEF8WGL3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000116560; ENSMUSP00000112259; ENSMUSG00000056201.

Organism-specific databases

MGIMGI:101757. Cfl1.

Phylogenomic databases

GeneTreeENSGT00440000033289.
OMAPPSCQTG.
OrthoDBEOG7353Z9.
TreeFamTF328601.

Gene expression databases

BgeeF8WGL3.

Family and domain databases

Gene3D3.40.20.10. 1 hit.
InterProIPR002108. ADF-H.
IPR029006. ADF-H/Gelsolin-like_dom.
IPR017904. ADF/Cofilin/Destrin.
IPR027234. Cofilin_1.
[Graphical view]
PANTHERPTHR11913. PTHR11913. 1 hit.
PTHR11913:SF17. PTHR11913:SF17. 1 hit.
PfamPF00241. Cofilin_ADF. 1 hit.
[Graphical view]
PRINTSPR00006. COFILIN.
SMARTSM00102. ADF. 1 hit.
[Graphical view]
PROSITEPS51263. ADF_H. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio35559761.
SOURCESearch...

Entry information

Entry nameF8WGL3_MOUSE
AccessionPrimary (citable) accession number: F8WGL3
Entry history
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 11, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)