ID   F8WEU5_HUMAN            Unreviewed;       173 AA.
AC   F8WEU5;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   27-MAR-2024, entry version 90.
DE   SubName: Full=Zinc finger protein 197 {ECO:0000313|Ensembl:ENSP00000334616.6};
GN   Name=ZNF197 {ECO:0000313|Ensembl:ENSP00000334616.6};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000334616.6, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000334616.6, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA   Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA   Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA   Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA   Sodergren E., Song X.Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA   Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA   Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA   Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA   Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA   Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA   Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA   Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O.,
RA   Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J., Zhang X.,
RA   Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA   Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000334616.6}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00187}.
CC   -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC       family. {ECO:0000256|ARBA:ARBA00006991}.
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DR   EMBL; AC099669; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000334075.6; ENSP00000334616.6; ENSG00000186448.15.
DR   Ensembl; ENST00000627858; ENSP00000486661; ENSG00000281709.
DR   UCSC; uc062ivk.1; human.
DR   HGNC; HGNC:12988; ZNF197.
DR   VEuPathDB; HostDB:ENSG00000186448; -.
DR   GeneTree; ENSGT00940000162801; -.
DR   HOGENOM; CLU_002678_53_4_1; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000186448; Expressed in cortical plate and 107 other cell types or tissues.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd07936; SCAN; 1.
DR   Gene3D; 1.10.4020.10; DNA breaking-rejoining enzymes; 1.
DR   InterPro; IPR003309; SCAN_dom.
DR   InterPro; IPR038269; SCAN_sf.
DR   PANTHER; PTHR45935; PROTEIN ZBED8-RELATED; 1.
DR   PANTHER; PTHR45935:SF15; SCAN DOMAIN-CONTAINING PROTEIN 3; 1.
DR   Pfam; PF02023; SCAN; 1.
DR   SMART; SM00431; SCAN; 1.
DR   SUPFAM; SSF47353; Retrovirus capsid dimerization domain-like; 1.
DR   PROSITE; PS50804; SCAN_BOX; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00187};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640}.
FT   DOMAIN          42..124
FT                   /note="SCAN box"
FT                   /evidence="ECO:0000259|PROSITE:PS50804"
SQ   SEQUENCE   173 AA;  19731 MW;  029268F9272DCE86 CRC64;
     MTRENVAHNA LRQEGLVKGK DDTWKWGTSF QGSSSSVWET SHLHFRQLRY HETSGPQEAL
     SRLRELCRRW LRPEARTKAQ ILELLVLEQF LSILPGEIRT WVQLHHPGSG EEAVALVEEL
     QKDLDGPAIQ VWLLFPPLCT VSSGRGHQCH EWGSRAAPLF SMQSFTAVLM LHT
//