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Protein
Submitted name:

PHD and RING finger domain-containing protein 1

Gene

PHRF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
PHD and RING finger domain-containing protein 1Imported
Gene namesi
Name:PHRF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000070047.11.
HGNCiHGNC:24351. PHRF1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000070047.

PTM / Processingi

Proteomic databases

MaxQBiF8WEF5.
PaxDbiF8WEF5.
PeptideAtlasiF8WEF5.
PRIDEiF8WEF5.

Expressioni

Gene expression databases

BgeeiENSG00000070047.
ExpressionAtlasiF8WEF5. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF8WEF5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini107 – 148RING-typeInterPro annotationAdd BLAST42
Domaini182 – 232PHD-typeInterPro annotationAdd BLAST51

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0825. Eukaryota.
ENOG410YZAI. LUCA.
GeneTreeiENSGT00530000063661.

Family and domain databases

Gene3Di3.30.40.10. 2 hits.
InterProiView protein in InterPro
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR001841. Znf_RING.
IPR013083. Znf_RING/FYVE/PHD.
IPR017907. Znf_RING_CS.
PfamiView protein in Pfam
PF00628. PHD. 1 hit.
PF13639. zf-RING_2. 1 hit.
SMARTiView protein in SMART
SM00249. PHD. 1 hit.
SM00184. RING. 2 hits.
SUPFAMiSSF57903. SSF57903. 1 hit.
PROSITEiView protein in PROSITE
PS50016. ZF_PHD_2. 1 hit.
PS00518. ZF_RING_1. 1 hit.
PS50089. ZF_RING_2. 1 hit.

Sequencei

Sequence statusi: Complete.

F8WEF5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDDDSLDELV ARSPGPDGHP QVGPADPAGD FESSVGSSGD SGDDSDSEHG
60 70 80 90 100
DGTDGEDEGA SEEEDLEDRS GSEDSEDDGE TLLEVAGTQG KLEAAGSFNS
110 120 130 140 150
DDDAESCPIC LNAFRDQAVG TPENCAHYFC LDCIVEWSKN ANSCPVDRTL
160 170 180 190 200
FKCICIRAQF GGKILRKIPV ENTKASEEEE DPTFCEVCGR SDREDRLLLC
210 220 230 240 250
DGCDAGYHME CLDPPLQEVP VDEWFCPECA APGVVLAADA GPVSEEEVSL
260 270 280 290 300
LLADVVPTTS RLRPRAGRTR AIARTRQSER VRATVNRNRI STARRVQHTP
310 320 330 340 350
GRLGSSLLDE AIEAVATGLS TAVYQRPLTP RTPARRKRKT RRRKKVPGRK
360 370 380 390 400
KTPSGPSAKS KSSATRSKKR QHRVKKRRGK KVKSEATTRS RIARTLGLRR
410 420 430 440 450
PVHSSCIPSV LKPVEPSLGL LRADIGAASL SLFGDPYELD PFDSEELSAN
460 470 480 490 500
PLSPLSAKRR ALSRSALQSH QPVARPVSVG LSRRRLPAAV PEPDLEEEPV
510 520 530 540 550
PDLLGSILSG QSLLMLGSSD VIIHRDGSLS AKRAAPVSFQ RNSGSLSRGE
560 570 580 590 600
EGFKGCLQPR ALPSGSPAQG PSGNRPQSTG LSCQGRSRTP ARTAGAPVRL
610 620 630 640 650
DLPAAPGAVQ ARNLSNGSVP GFRQSHSPWF NGTNKHTLPL ASAASKISSR
660 670 680 690 700
DSKPPCRSVV PGPPLKPAPR RTDISELPRI PKIRRDDGGG RRDAAPAHGQ
710 720 730 740 750
SIEIPSACIS RLTGREGTGQ PGRGTRAESE ASSRVPREPG VHTGSSRPPA
760 770 780 790 800
PSSHGSLAPL GPSRGKGVGS TFESFRINIP GNMAHSSQLS SPGFCNTFRP
810 820 830 840 850
VDDKEQRKEN PSPLFSIKKT KQLRSEVYDP SDPTGSDSSA PGSSPERSGP
860 870 880 890 900
GLLPSEITRT ISINSPKAQT VQAVRCVTSY TVESIFGTEP EPPLGPSSAM
910 920 930 940 950
SKLRGAVAAE GASDTEREEP TESQGLAARL RRPSPPEPWD EEDGASCSTF
960 970 980 990 1000
FGSEERTVTC VTVVEPEAPP SPDVLQAATH RVVELRPPSR SRSTSSSRSR
1010 1020 1030 1040 1050
KKAKRKRVSR EHGRTRSGTR SESRDRSSRS ASPSVGEERP RRQRSKAKSR
1060 1070 1080 1090 1100
RSSSDRSSSR ERAKRKKAKD KSREHRRGPW GHSRRTSRSR SGSPGSSSYE
1110 1120 1130 1140 1150
HYESRKKKKR RSASRPRGRE CSPTSSLERL CRHKHQRERS HERPDRKESV
1160 1170 1180 1190 1200
AWPRDRRKRR SRSPSSEHRA REHRRPRSRE KWPQTRSHSP ERKGAVREAS
1210 1220 1230 1240 1250
PAPLAQGEPG REDLPTRLPA LGEAHVSPEV ATADKAPLQA PPVLEVAAEC
1260 1270 1280 1290 1300
EPDDLDLDYG DSVEAGHVFD DFSSDAVFIQ LDDMSSPPSP ESTDSSPERD
1310 1320 1330 1340 1350
FPLKPALPPA SLAVAAIQRE VSLMHDEDPS QPPPLPEGTQ EPHLLRPDAA
1360 1370 1380 1390 1400
EKAEAPSSPD VAPAGKEDSP SASGRVQEAA RPEEVVSQTP LLRSRALVKR
1410 1420 1430 1440 1450
VTWNLQESES SAPAEDRAPR APLHRPQKPR EGAWDMEDVA PTGVRQVFSE
1460 1470 1480 1490 1500
LPFPSHVLPE PGFPDTDPSQ VYSPGLPPAP AQPSSIPPCA LVSQPTVQFI
1510 1520 1530 1540 1550
LQGSLPLVGC GAAQTLAPVP AALTPASEPA SQATAASNSE EKTPAPRLAA
1560 1570 1580 1590 1600
EKTKKEEYMK KLHMQERAVE EVKLAIKPFY QKREVTKEEY KDILRKAVQK
1610 1620 1630 1640
ICHSKSGEIN PVKVANLVKA YVDKYRHMRR HKKPEAGEEP PTQGAEG
Length:1,647
Mass (Da):178,450
Last modified:September 21, 2011 - v1
Checksum:iF2089FFC6FA0265F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006284 Genomic DNA. No translation available.
RefSeqiNP_001273511.1. NM_001286582.1.
UniGeneiHs.325838.

Genome annotation databases

EnsembliENST00000413872; ENSP00000388589; ENSG00000070047.
GeneIDi57661.
UCSCiuc010qwd.4. human.

Similar proteinsi

Entry informationi

Entry nameiF8WEF5_HUMAN
AccessioniPrimary (citable) accession number: F8WEF5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 25, 2017
This is version 54 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported