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Protein
Submitted name:

Transient receptor potential cation channel subfamily M member 8

Gene

TRPM8

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Biological processi

  1. cation transport Source: InterPro
  2. detection of temperature stimulus Source: InterPro
  3. sensory perception of temperature stimulus Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transient receptor potential cation channel subfamily M member 8Imported
Gene namesi
Name:TRPM8Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:17961. TRPM8.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiF8WD55.
ExpressionAtlasiF8WD55. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF8WD55.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000119127.

Family and domain databases

InterProiIPR029603. TRPM8.
[Graphical view]
PANTHERiPTHR13800:SF9. PTHR13800:SF9. 1 hit.

Sequencei

Sequence statusi: Complete.

F8WD55-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFRAARLSM RNRRNDTLDS TRTLYSSASR STDLSYSESD LVNFIQANFK
60 70 80 90 100
KRECVFFTKD SKATENVCKC GYAQSQHMEG TQINQSEKWN YKKHTKEFPT
110 120 130 140 150
DAFGDIQFET LGKKGKYIRL SCDTDAEILY ELLTQHWHLK TPNLVISVTG
160 170 180 190 200
GAKNFALKPR MRKIFSRLIY IAQSKGAWIL TGGTHYGLMK YIGEVVRDNT
210 220 230 240 250
ISRSSEENIV AIGIAAWGMV SNRDTLIRNC DAEGYFLAQY LMDDFTRDPL
260 270 280 290 300
YILDNNHTHL LLVDNGCHGH PTVEAKLRNQ LEKYISERTI QDSNYGGKIP
310 320
IVCFAQGGGK ETLKSRRFGR RISVT
Length:325
Mass (Da):37,063
Last modified:September 21, 2011 - v1
Checksum:iCBF98C621AB452AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005538 Genomic DNA. No translation available.
KF510796 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000444298; ENSP00000396745; ENSG00000144481.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005538 Genomic DNA. No translation available.
KF510796 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF8WD55.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000444298; ENSP00000396745; ENSG00000144481.

Organism-specific databases

HGNCiHGNC:17961. TRPM8.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00760000119127.

Miscellaneous databases

NextBioi35513934.

Gene expression databases

BgeeiF8WD55.
ExpressionAtlasiF8WD55. baseline and differential.

Family and domain databases

InterProiIPR029603. TRPM8.
[Graphical view]
PANTHERiPTHR13800:SF9. PTHR13800:SF9. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF8WD55_HUMAN
AccessioniPrimary (citable) accession number: F8WD55
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: January 7, 2015
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.