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Protein
Submitted name:

Vesicle-associated membrane protein 2

Gene

VAMP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Vesicle-associated membrane protein 2Imported
Gene namesi
Name:VAMP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 17

Organism-specific databases

EuPathDBiHostDB:ENSG00000220205.8
HGNCiHGNC:12643 VAMP2

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei95 – 116HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000220205

PTM / Processingi

Proteomic databases

EPDiF8WCA0
MaxQBiF8WCA0
PeptideAtlasiF8WCA0
PRIDEiF8WCA0

Expressioni

Gene expression databases

BgeeiENSG00000220205
ExpressionAtlasiF8WCA0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8WCA0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 93V-SNARE coiled-coil homologyInterPro annotationAdd BLAST61

Keywords - Domaini

Coiled coilPROSITE-ProRule annotationSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0860 Eukaryota
COG5143 LUCA
GeneTreeiENSGT00550000074449
OrthoDBiEOG091G0MPE
PhylomeDBiF8WCA0

Family and domain databases

InterProiView protein in InterPro
IPR001388 Synaptobrevin
IPR016444 Synaptobrevin/VAMP
IPR028717 VAMP2
PANTHERiPTHR21136:SF91 PTHR21136:SF91, 1 hit
PfamiView protein in Pfam
PF00957 Synaptobrevin, 1 hit
PIRSFiPIRSF005409 Synaptobrevin_euk, 1 hit
PRINTSiPR00219 SYNAPTOBREVN
PROSITEiView protein in PROSITE
PS00417 SYNAPTOBREVIN, 1 hit
PS50892 V_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

F8WCA0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRSATAATA PPAAPAGEGG PPAPPPNLTS NRRLQQTQAQ VDEVVDIMRV
60 70 80 90 100
NVDKVLERDQ KLSELDDRAD ALQAGASQFE TSAAKLKRKY WWKNLKMMII
110
LGVICAIILI IIIVYFST
Length:118
Mass (Da):12,934
Last modified:September 21, 2011 - v1
Checksum:iCCC93D81D8785143
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC129492 Genomic DNA No translation available.
RefSeqiNP_001317054.1, NM_001330125.1
UniGeneiHs.25348

Genome annotation databases

EnsembliENST00000488857; ENSP00000418572; ENSG00000220205
GeneIDi6844
UCSCiuc060ayt.1 human

Similar proteinsi

Entry informationi

Entry nameiF8WCA0_HUMAN
AccessioniPrimary (citable) accession number: F8WCA0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: April 25, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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