SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

F8W8R6

- F8W8R6_HUMAN

UniProt

F8W8R6 - F8W8R6_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Lysine-specific demethylase 6A
Gene
KDM6A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Lysine-specific demethylase 6AImported
Gene namesi
Name:KDM6AImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome X

Organism-specific databases

HGNCiHGNC:12637. KDM6A.

Expressioni

Gene expression databases

ArrayExpressiF8W8R6.
BgeeiF8W8R6.

Structurei

3D structure databases

ProteinModelPortaliF8W8R6.
SMRiF8W8R6. Positions 893-1402.

Family & Domainsi

Sequence similaritiesi

Contains JmjC domain.SAAS annotations

Phylogenomic databases

KOiK11447.
OMAiHHTVDQL.
PhylomeDBiF8W8R6.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
InterProiIPR003347. JmjC_dom.
IPR029517. KDM6A.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR14017:SF9. PTHR14017:SF9. 1 hit.
PfamiPF02373. JmjC. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view]
SMARTiSM00558. JmjC. 1 hit.
SM00028. TPR. 6 hits.
[Graphical view]
PROSITEiPS51184. JMJC. 1 hit.
PS50005. TPR. 7 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8W8R6-1 [UniParc]FASTAAdd to Basket

« Hide

MKSCGVSLAT AAAAAAAFGD EEKKMAAGKA SGESEEASPS LTAEEREALG     50
GLDSRLFGFV RFHEDGARTK ALLGKAVRCY ESLILKAEGK VESDFFCQLG 100
HFNLLLEDYP KALSAYQRYY SLQSDYWKNA AFLYGLGLVY FHYNAFQWAI 150
KAFQEVLYVD PSFCRAKEIH LRLGLMFKVN TDYESSLKHF QLALVDCNPC 200
TLSNAEIQFH IAHLYETQRK YHSAKEAYEQ LLQTENLSAQ VKATVLQQLG 250
WMHHTVDLLG DKATKESYAI QYLQKSLEAD PNSGQSWYFL GRCYSSIGKV 300
QDAFISYRQS IDKSEASADT WCSIGVLYQQ QNQPMDALQA YICAVQLDHG 350
HAAAWMDLGT LYESCNQPQD AIKCYLNATR SKSCSNTSAL AARIKYLQAC 400
KPHHPNTEPV LGLSQTPISQ QSLPLHMIPS SQVDDLSSPA KRKRTSSPTK 450
NTSDNWSGGH AVSHPPVQQQ AHSWCLTPQK LQHLEQLRAN RNNLNPAQKL 500
MLEQLESQFV LMQQHQMRPT GVAQVRSTGI PNGPTADSSL PTNSVSGQQP 550
QLALTRVPSV SQPGVRPACP GQPLANGPFS AGHVPCSTSR TLGSTDTILI 600
GNNHITGSGS NGNVPYLQRN ALTLPHNRTN LTSSAEEPWK NQLSNSTQGL 650
HKGQSSHSAG PNGERPLSST GPSQHLQAAG SGIQNQNGHP TLPSNSVTQG 700
AALNHLSSHT ATSGGQQGIT LTKESKPSGN ILTVPETSRH TGETPNSTAS 750
VEGLPNHVHQ MTADAVCSPS HGDSKSPGLL SSDNPQLSAL LMGKANNNVG 800
TGTCDKVNNI HPAVHTKTDN SVASSPSSAI STATPSPKST EQTTTNSVTS 850
LNSPHSGLHT INGEGMEESQ SPMKTDLLLV NHKPSPQIIP SMSVSIYPSS 900
AEVLKACRNL GKNGLSNSSI LLDKCPPPRP PSSPYPPLPK DKLNPPTPSI 950
YLENKRDAFF PPLHQFCTNP NNPVTVIRGL AGALKLDLGL FSTKTLVEAN 1000
NEHMVEVRTQ LLQPADENWD PTGTKKIWHC ESNRSHTTIA KYAQYQASSF 1050
QESLREENEK RSHHKDHSDS ESTSSDNSGR RRKGPFKTIK FGTNIDLSDD 1100
KKWKLQLHEL TKLPAFVRVV SAGNLLSHVG HTILGMNTVQ LYMKVPGSRT 1150
PGHQENNNFC SVNINIGPGD CEWFVVPEGY WGVLNDFCEK NNLNFLMGSW 1200
WPNLEDLYEA NVPVYRFIQR PGDLVWINAG TVHWVQAIGW CNNIAWNVGP 1250
LTACQYKLAV ERYEWNKLQS VKSIVPMVHL SWNMARNIKV SDPKLFEMIK 1300
YCLLRTLKQC QTLREALIAA GKEIIWHGRT KEEPAHYCSI CEVEVFDLLF 1350
VTNESNSRKT YIVHCQDCAR KTSGNLENFV VLEQYKMEDL MQVYDQFTLA 1400
PPLPSASS 1408
Length:1,408
Mass (Da):154,928
Last modified:September 21, 2011 - v1
Checksum:i12E2DA673F80E91F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC136488 Genomic DNA. No translation available.
AL133545 Genomic DNA. No translation available.
AL138744 Genomic DNA. No translation available.
RefSeqiNP_001278345.1. NM_001291416.1.
UniGeneiHs.522616.

Genome annotation databases

EnsembliENST00000382899; ENSP00000372355; ENSG00000147050.
GeneIDi7403.
KEGGihsa:7403.
UCSCiuc011mlb.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC136488 Genomic DNA. No translation available.
AL133545 Genomic DNA. No translation available.
AL138744 Genomic DNA. No translation available.
RefSeqi NP_001278345.1. NM_001291416.1.
UniGenei Hs.522616.

3D structure databases

ProteinModelPortali F8W8R6.
SMRi F8W8R6. Positions 893-1402.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000382899 ; ENSP00000372355 ; ENSG00000147050 .
GeneIDi 7403.
KEGGi hsa:7403.
UCSCi uc011mlb.2. human.

Organism-specific databases

CTDi 7403.
HGNCi HGNC:12637. KDM6A.
GenAtlasi Search...

Phylogenomic databases

KOi K11447.
OMAi HHTVDQL.
PhylomeDBi F8W8R6.

Miscellaneous databases

ChiTaRSi KDM6A. human.
GenomeRNAii 7403.
NextBioi 35512944.

Gene expression databases

ArrayExpressi F8W8R6.
Bgeei F8W8R6.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
InterProi IPR003347. JmjC_dom.
IPR029517. KDM6A.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR14017:SF9. PTHR14017:SF9. 1 hit.
Pfami PF02373. JmjC. 1 hit.
PF13181. TPR_8. 1 hit.
[Graphical view ]
SMARTi SM00558. JmjC. 1 hit.
SM00028. TPR. 6 hits.
[Graphical view ]
PROSITEi PS51184. JMJC. 1 hit.
PS50005. TPR. 7 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiF8W8R6_HUMAN
AccessioniPrimary (citable) accession number: F8W8R6
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi