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F8W4B7

- F8W4B7_DANRE

UniProt

F8W4B7 - F8W4B7_DANRE

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Protein
Submitted name:

Uncharacterized protein

Gene
hdac6
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. angiogenesis Source: ZFIN
  2. protein deacetylation Source: ZFIN
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotations

Enzyme and pathway databases

ReactomeiREACT_225331. HSF1 activation.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:hdac6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 8

Organism-specific databases

ZFINiZDB-GENE-030131-3232. hdac6.

PTM / Processingi

Proteomic databases

PRIDEiF8W4B7.

Expressioni

Gene expression databases

BgeeiF8W4B7.

Structurei

3D structure databases

ProteinModelPortaliF8W4B7.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000062809.
OMAiLQENWVC.
OrthoDBiEOG7992PT.
TreeFamiTF106173.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
PROSITEiPS50271. ZF_UBP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8W4B7-1 [UniParc]FASTAAdd to Basket

« Hide

MDAVPDTKGS SGPPRGTPET KNNKKNLQEA RRKGRMDRSK AEEEMSNELQ     50
NLDVQGKSKA TGTGLVYVDA FTRFHCLWDA SHPECPARVS TVMEMLETEG 100
LLGRCVQVEA RAVTEDELLL VHTKEYVELM KSTQNMTEEE LKTLAEKYDS 150
VYLHPGFFSS ACLSVGSVLQ LVDKVMTSQL RNGFSINRPP GHHAQADKMN 200
GFCMFNNLAI AARYAQKRHR VQRVLIVDWD VHHGQGIQYI FEEDPSVLYF 250
SVHRYEDGSF WPHLKESDSS SVGSGAGQGY NINLPWNKVG MESGDYITAF 300
QQLLLPVAYE FQPQLVLVAA GFDAVIGDPK GGMQVSPECF SILTHMLKGV 350
AQGRLVLALE GGYNLQSTAE GVCASMRSLL GDPCPHLPSS GAPCESALKS 400
ISKTISDLYP FWKSLQTFEG GPLSEVSPLP APVCAEVKVS SPITGLVYDQ 450
RMMLHHNMWD SHHPELPQRI SRIFSRHEEL RLLSRCHRIP ARLATEEELA 500
LCHSSKHISI IKSSEHMKPR DLNRLGDEYN SIFISNESYT CALLAAGSCF 550
NSAQAILTGQ VRNAVAIVRP PGHHAEKDTA CGFCFFNTAA LTARYAQSIT 600
RESLRVLIVD WDVHHGNGTQ HIFEEDDSVL YISLHRYEDG AFFPNSEDAN 650
YDKVGLGKGR GYNVNIPWNG GKMGDPEYMA AFHHLVMPIA REFAPELVLV 700
SAGFDAARGD PLGGFQVTPE GYAHLTHQLM SLAAGRVLII LEGGYNLTSI 750
SESMSMCTSM LLGDSPPSLD HLTPLKTSAT VSINNVLRAH APFWSSLRVN 800
IPESLRLSLP SPKPKGKCTP GGKGKKSPRQ STPSQSPGQA THRPDQSGFD 850
ELTADLLSLN LNTSTSSNTS PESVAVGGAR RKVKPNTHRV SAGLESESPL 900
KLNPEKAGAG DDTDVKAETP NRSISEPVVT CDSSAVKDQE SLVLEAAGGN 950
TVQSVLERVF GAQATDVDTM YVVDPLPWCP HLESVRPVPA GGIDVFQPCE 1000
ECGGEAENWI CLFCYKVLCG RYVNQHMVTH GQESGHPVVL SFADLSVWCY 1050
ACESYVHNKV LHEAKNAAHL VKFGEGIHPF N 1081
Length:1,081
Mass (Da):118,375
Last modified:September 21, 2011 - v1
Checksum:i8807F58CDD0AEFB0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX469901 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000148993; ENSDARP00000124246; ENSDARG00000008384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX469901 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F8W4B7.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F8W4B7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000148993 ; ENSDARP00000124246 ; ENSDARG00000008384 .

Organism-specific databases

ZFINi ZDB-GENE-030131-3232. hdac6.

Phylogenomic databases

GeneTreei ENSGT00530000062809.
OMAi LQENWVC.
OrthoDBi EOG7992PT.
TreeFami TF106173.

Enzyme and pathway databases

Reactomei REACT_225331. HSF1 activation.

Miscellaneous databases

NextBioi 20885908.

Gene expression databases

Bgeei F8W4B7.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProi IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
[Graphical view ]
PRINTSi PR01270. HDASUPER.
PROSITEi PS50271. ZF_UBP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiF8W4B7_DANRE
AccessioniPrimary (citable) accession number: F8W4B7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 3, 2014
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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