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F8W4B7

- F8W4B7_DANRE

UniProt

F8W4B7 - F8W4B7_DANRE

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Protein
Submitted name:

Uncharacterized protein

Gene

hdac6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. hydrolase activity Source: UniProtKB-KW
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. angiogenesis Source: ZFIN
  2. protein deacetylation Source: ZFIN
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseSAAS annotation

Enzyme and pathway databases

ReactomeiREACT_225331. HSF1 activation.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:hdac6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 8

Organism-specific databases

ZFINiZDB-GENE-030131-3232. hdac6.

PTM / Processingi

Proteomic databases

PRIDEiF8W4B7.

Expressioni

Gene expression databases

BgeeiF8W4B7.

Structurei

3D structure databases

ProteinModelPortaliF8W4B7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000062809.
InParanoidiF8W4B7.
OMAiLQENWVC.
OrthoDBiEOG7992PT.
TreeFamiTF106173.

Family and domain databases

Gene3Di3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProiIPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view]
PANTHERiPTHR10625. PTHR10625. 1 hit.
PfamiPF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
[Graphical view]
PRINTSiPR01270. HDASUPER.
PROSITEiPS50271. ZF_UBP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

F8W4B7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDAVPDTKGS SGPPRGTPET KNNKKNLQEA RRKGRMDRSK AEEEMSNELQ
60 70 80 90 100
NLDVQGKSKA TGTGLVYVDA FTRFHCLWDA SHPECPARVS TVMEMLETEG
110 120 130 140 150
LLGRCVQVEA RAVTEDELLL VHTKEYVELM KSTQNMTEEE LKTLAEKYDS
160 170 180 190 200
VYLHPGFFSS ACLSVGSVLQ LVDKVMTSQL RNGFSINRPP GHHAQADKMN
210 220 230 240 250
GFCMFNNLAI AARYAQKRHR VQRVLIVDWD VHHGQGIQYI FEEDPSVLYF
260 270 280 290 300
SVHRYEDGSF WPHLKESDSS SVGSGAGQGY NINLPWNKVG MESGDYITAF
310 320 330 340 350
QQLLLPVAYE FQPQLVLVAA GFDAVIGDPK GGMQVSPECF SILTHMLKGV
360 370 380 390 400
AQGRLVLALE GGYNLQSTAE GVCASMRSLL GDPCPHLPSS GAPCESALKS
410 420 430 440 450
ISKTISDLYP FWKSLQTFEG GPLSEVSPLP APVCAEVKVS SPITGLVYDQ
460 470 480 490 500
RMMLHHNMWD SHHPELPQRI SRIFSRHEEL RLLSRCHRIP ARLATEEELA
510 520 530 540 550
LCHSSKHISI IKSSEHMKPR DLNRLGDEYN SIFISNESYT CALLAAGSCF
560 570 580 590 600
NSAQAILTGQ VRNAVAIVRP PGHHAEKDTA CGFCFFNTAA LTARYAQSIT
610 620 630 640 650
RESLRVLIVD WDVHHGNGTQ HIFEEDDSVL YISLHRYEDG AFFPNSEDAN
660 670 680 690 700
YDKVGLGKGR GYNVNIPWNG GKMGDPEYMA AFHHLVMPIA REFAPELVLV
710 720 730 740 750
SAGFDAARGD PLGGFQVTPE GYAHLTHQLM SLAAGRVLII LEGGYNLTSI
760 770 780 790 800
SESMSMCTSM LLGDSPPSLD HLTPLKTSAT VSINNVLRAH APFWSSLRVN
810 820 830 840 850
IPESLRLSLP SPKPKGKCTP GGKGKKSPRQ STPSQSPGQA THRPDQSGFD
860 870 880 890 900
ELTADLLSLN LNTSTSSNTS PESVAVGGAR RKVKPNTHRV SAGLESESPL
910 920 930 940 950
KLNPEKAGAG DDTDVKAETP NRSISEPVVT CDSSAVKDQE SLVLEAAGGN
960 970 980 990 1000
TVQSVLERVF GAQATDVDTM YVVDPLPWCP HLESVRPVPA GGIDVFQPCE
1010 1020 1030 1040 1050
ECGGEAENWI CLFCYKVLCG RYVNQHMVTH GQESGHPVVL SFADLSVWCY
1060 1070 1080
ACESYVHNKV LHEAKNAAHL VKFGEGIHPF N
Length:1,081
Mass (Da):118,375
Last modified:September 21, 2011 - v1
Checksum:i8807F58CDD0AEFB0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX469901 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSDART00000148993; ENSDARP00000124246; ENSDARG00000008384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX469901 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali F8W4B7.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi F8W4B7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000148993 ; ENSDARP00000124246 ; ENSDARG00000008384 .

Organism-specific databases

ZFINi ZDB-GENE-030131-3232. hdac6.

Phylogenomic databases

GeneTreei ENSGT00530000062809.
InParanoidi F8W4B7.
OMAi LQENWVC.
OrthoDBi EOG7992PT.
TreeFami TF106173.

Enzyme and pathway databases

Reactomei REACT_225331. HSF1 activation.

Miscellaneous databases

NextBioi 20885908.

Gene expression databases

Bgeei F8W4B7.

Family and domain databases

Gene3Di 3.30.40.10. 1 hit.
3.40.800.20. 2 hits.
InterProi IPR000286. His_deacetylse.
IPR023801. His_deacetylse_dom.
IPR013083. Znf_RING/FYVE/PHD.
IPR001607. Znf_UBP.
[Graphical view ]
PANTHERi PTHR10625. PTHR10625. 1 hit.
Pfami PF00850. Hist_deacetyl. 2 hits.
PF02148. zf-UBP. 1 hit.
[Graphical view ]
PRINTSi PR01270. HDASUPER.
PROSITEi PS50271. ZF_UBP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.
  2. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.

Entry informationi

Entry nameiF8W4B7_DANRE
AccessioniPrimary (citable) accession number: F8W4B7
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: October 29, 2014
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3