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F8W4B7

- F8W4B7_DANRE

UniProt

F8W4B7 - F8W4B7_DANRE

Protein
Submitted name:

Uncharacterized protein

Gene

hdac6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 22 (01 Oct 2014)
      Sequence version 1 (21 Sep 2011)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. hydrolase activity Source: UniProtKB-KW
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. angiogenesis Source: ZFIN
    2. protein deacetylation Source: ZFIN

    Keywords - Molecular functioni

    HydrolaseSAAS annotation

    Enzyme and pathway databases

    ReactomeiREACT_225331. HSF1 activation.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Name:hdac6Imported
    OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
    Taxonomic identifieri7955 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
    ProteomesiUP000000437: Chromosome 8

    Organism-specific databases

    ZFINiZDB-GENE-030131-3232. hdac6.

    PTM / Processingi

    Proteomic databases

    PRIDEiF8W4B7.

    Expressioni

    Gene expression databases

    BgeeiF8W4B7.

    Structurei

    3D structure databases

    ProteinModelPortaliF8W4B7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000062809.
    OMAiLQENWVC.
    OrthoDBiEOG7992PT.
    TreeFamiTF106173.

    Family and domain databases

    Gene3Di3.30.40.10. 1 hit.
    3.40.800.20. 2 hits.
    InterProiIPR000286. His_deacetylse.
    IPR023801. His_deacetylse_dom.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR001607. Znf_UBP.
    [Graphical view]
    PANTHERiPTHR10625. PTHR10625. 1 hit.
    PfamiPF00850. Hist_deacetyl. 2 hits.
    PF02148. zf-UBP. 1 hit.
    [Graphical view]
    PRINTSiPR01270. HDASUPER.
    PROSITEiPS50271. ZF_UBP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    F8W4B7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDAVPDTKGS SGPPRGTPET KNNKKNLQEA RRKGRMDRSK AEEEMSNELQ     50
    NLDVQGKSKA TGTGLVYVDA FTRFHCLWDA SHPECPARVS TVMEMLETEG 100
    LLGRCVQVEA RAVTEDELLL VHTKEYVELM KSTQNMTEEE LKTLAEKYDS 150
    VYLHPGFFSS ACLSVGSVLQ LVDKVMTSQL RNGFSINRPP GHHAQADKMN 200
    GFCMFNNLAI AARYAQKRHR VQRVLIVDWD VHHGQGIQYI FEEDPSVLYF 250
    SVHRYEDGSF WPHLKESDSS SVGSGAGQGY NINLPWNKVG MESGDYITAF 300
    QQLLLPVAYE FQPQLVLVAA GFDAVIGDPK GGMQVSPECF SILTHMLKGV 350
    AQGRLVLALE GGYNLQSTAE GVCASMRSLL GDPCPHLPSS GAPCESALKS 400
    ISKTISDLYP FWKSLQTFEG GPLSEVSPLP APVCAEVKVS SPITGLVYDQ 450
    RMMLHHNMWD SHHPELPQRI SRIFSRHEEL RLLSRCHRIP ARLATEEELA 500
    LCHSSKHISI IKSSEHMKPR DLNRLGDEYN SIFISNESYT CALLAAGSCF 550
    NSAQAILTGQ VRNAVAIVRP PGHHAEKDTA CGFCFFNTAA LTARYAQSIT 600
    RESLRVLIVD WDVHHGNGTQ HIFEEDDSVL YISLHRYEDG AFFPNSEDAN 650
    YDKVGLGKGR GYNVNIPWNG GKMGDPEYMA AFHHLVMPIA REFAPELVLV 700
    SAGFDAARGD PLGGFQVTPE GYAHLTHQLM SLAAGRVLII LEGGYNLTSI 750
    SESMSMCTSM LLGDSPPSLD HLTPLKTSAT VSINNVLRAH APFWSSLRVN 800
    IPESLRLSLP SPKPKGKCTP GGKGKKSPRQ STPSQSPGQA THRPDQSGFD 850
    ELTADLLSLN LNTSTSSNTS PESVAVGGAR RKVKPNTHRV SAGLESESPL 900
    KLNPEKAGAG DDTDVKAETP NRSISEPVVT CDSSAVKDQE SLVLEAAGGN 950
    TVQSVLERVF GAQATDVDTM YVVDPLPWCP HLESVRPVPA GGIDVFQPCE 1000
    ECGGEAENWI CLFCYKVLCG RYVNQHMVTH GQESGHPVVL SFADLSVWCY 1050
    ACESYVHNKV LHEAKNAAHL VKFGEGIHPF N 1081
    Length:1,081
    Mass (Da):118,375
    Last modified:September 21, 2011 - v1
    Checksum:i8807F58CDD0AEFB0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX469901 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSDART00000148993; ENSDARP00000124246; ENSDARG00000008384.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX469901 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali F8W4B7.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi F8W4B7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSDART00000148993 ; ENSDARP00000124246 ; ENSDARG00000008384 .

    Organism-specific databases

    ZFINi ZDB-GENE-030131-3232. hdac6.

    Phylogenomic databases

    GeneTreei ENSGT00530000062809.
    OMAi LQENWVC.
    OrthoDBi EOG7992PT.
    TreeFami TF106173.

    Enzyme and pathway databases

    Reactomei REACT_225331. HSF1 activation.

    Miscellaneous databases

    NextBioi 20885908.

    Gene expression databases

    Bgeei F8W4B7.

    Family and domain databases

    Gene3Di 3.30.40.10. 1 hit.
    3.40.800.20. 2 hits.
    InterProi IPR000286. His_deacetylse.
    IPR023801. His_deacetylse_dom.
    IPR013083. Znf_RING/FYVE/PHD.
    IPR001607. Znf_UBP.
    [Graphical view ]
    PANTHERi PTHR10625. PTHR10625. 1 hit.
    Pfami PF00850. Hist_deacetyl. 2 hits.
    PF02148. zf-UBP. 1 hit.
    [Graphical view ]
    PRINTSi PR01270. HDASUPER.
    PROSITEi PS50271. ZF_UBP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Ensembl
      Submitted (JUL-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: TuebingenImported.
    2. "The zebrafish reference genome sequence and its relationship to the human genome."
      Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
      , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
      Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TuebingenImported.

    Entry informationi

    Entry nameiF8W4B7_DANRE
    AccessioniPrimary (citable) accession number: F8W4B7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: September 21, 2011
    Last sequence update: September 21, 2011
    Last modified: October 1, 2014
    This is version 22 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3