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Protein
Submitted name:

Diacylglycerol kinase alpha

Gene

DGKA

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi123 – 134PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Diacylglycerol kinase alphaImported
Gene namesi
Name:DGKAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000065357.19.
HGNCiHGNC:2849. DGKA.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000065357.

PTM / Processingi

Proteomic databases

MaxQBiF8W1H7.
PaxDbiF8W1H7.
PeptideAtlasiF8W1H7.
PRIDEiF8W1H7.

Expressioni

Gene expression databases

BgeeiENSG00000065357.
ExpressionAtlasiF8W1H7. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF8W1H7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini110 – 145EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG1169. Eukaryota.
ENOG410XQVB. LUCA.
GeneTreeiENSGT00760000119050.

Family and domain databases

InterProiView protein in InterPro
IPR029477. DAG_kinase_typeI_N.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
PfamiView protein in Pfam
PF14513. DAG_kinase_N. 2 hits.
SUPFAMiSSF47473. SSF47473. 2 hits.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 1 hit.
PS50222. EF_HAND_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

F8W1H7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKERGLISP SDFAQLQKYM EYSTKKVSDV LKLFEDGEMA KYVQGDAIGY
60 70 80 90 100
EGFQQFLKIY LEVDNVPRHL SLALFQSFET GHCLNETNVT KDVVCLNDVS
110 120 130 140
CYFSLLEGGR PEDKLEFTFK LYDTDRNGIL DSSEVDKIIL QMMRVAE
Length:147
Mass (Da):16,844
Last modified:September 21, 2011 - v1
Checksum:i972574E2CF9232AD
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei147Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC025162 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000549368; ENSP00000447050; ENSG00000065357.
UCSCiuc058pda.1. human.

Similar proteinsi

Entry informationi

Entry nameiF8W1H7_HUMAN
AccessioniPrimary (citable) accession number: F8W1H7
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: September 27, 2017
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported