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Protein
Submitted name:

Zinc finger protein 606

Gene

ZNF606

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zinc finger protein 606Imported
Gene namesi
Name:ZNF606Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 19

Organism-specific databases

HGNCiHGNC:25879. ZNF606.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000166704.

PTM / Processingi

Proteomic databases

PaxDbiF8W1C8.
PeptideAtlasiF8W1C8.
PRIDEiF8W1C8.

Expressioni

Gene expression databases

BgeeiENSG00000166704.
ExpressionAtlasiF8W1C8. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000343617.

Structurei

3D structure databases

ProteinModelPortaliF8W1C8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 133KRABInterPro annotationAdd BLAST72
Domaini289 – 316C2H2-typeInterPro annotationAdd BLAST28
Domaini317 – 344C2H2-typeInterPro annotationAdd BLAST28
Domaini400 – 427C2H2-typeInterPro annotationAdd BLAST28
Domaini428 – 455C2H2-typeInterPro annotationAdd BLAST28
Domaini456 – 483C2H2-typeInterPro annotationAdd BLAST28
Domaini484 – 508C2H2-typeInterPro annotationAdd BLAST25

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00860000133773.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 7 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 1 hit.
PF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

F8W1C8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAINPWASW GALTDQSWGM TAVDPWASWA LCPQYPAWHV EGSLEEGRRA
60 70 80 90 100
TGLPAAQVQE PVTFKDVAVD FTQEEWGQLD LVQRTLYRDV MLETYGHLLS
110 120 130 140 150
VGNQIAKPEV ISLLEQGEEP WSVEQACPQR TCPEWVRNLE SKALIPAQSI
160 170 180 190 200
FEEEQSHGMK LERYIWDDPW FSRLEVLGCK DQLEMYHMNQ STAMRQMVFM
210 220 230 240 250
QKQVLSQRSS EFCGLGAEFS QNLNFVPSQR VSQIEHFYKP DTHAQSWRCD
260 270 280 290 300
SAIMYADKVT CENNDYDKTV YQSIQPIYPA RIQTGDNLFK CTDAVKSFNH
310 320 330 340 350
IIHFGDHKGI HTGEKLYEYK ECHQIFNQSP SFNEHPRLHV GENQYNYKEY
360 370 380 390 400
ENIFYFSSFM EHQKIGTVEK AYKYNEWEKV FGYDSFLTQH TSTYTAEKPY
410 420 430 440 450
DYNECGTSFI WSSYLIQHKK THTGEKPYEC DKCGKVFRNR SALTKHERTH
460 470 480 490 500
TGIKPYECNK CGKAFSWNSH LIVHKRIHTG EKPYVCNECG KSFNWNSHLI

GHQRTHTG
Length:508
Mass (Da):59,161
Last modified:September 21, 2011 - v1
Checksum:iC63A7695C5BD1921
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei508Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008969 Genomic DNA. No translation available.
AC010326 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000551380; ENSP00000446972; ENSG00000166704.
UCSCiuc061dow.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008969 Genomic DNA. No translation available.
AC010326 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliF8W1C8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000343617.

Proteomic databases

PaxDbiF8W1C8.
PeptideAtlasiF8W1C8.
PRIDEiF8W1C8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000551380; ENSP00000446972; ENSG00000166704.
UCSCiuc061dow.1. human.

Organism-specific databases

HGNCiHGNC:25879. ZNF606.
OpenTargetsiENSG00000166704.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00860000133773.

Miscellaneous databases

ChiTaRSiZNF606. human.

Gene expression databases

BgeeiENSG00000166704.
ExpressionAtlasiF8W1C8. baseline and differential.

Family and domain databases

CDDicd07765. KRAB_A-box. 1 hit.
Gene3Di3.30.160.60. 7 hits.
InterProiIPR001909. KRAB.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 1 hit.
PF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiF8W1C8_HUMAN
AccessioniPrimary (citable) accession number: F8W1C8
Entry historyi
Integrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 30, 2016
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.