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Protein
Submitted name:

Rap guanine nucleotide exchange factor 3

Gene

RAPGEF3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Rap guanine nucleotide exchange factor 3Imported
Gene namesi
Name:RAPGEF3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000079337.15.
HGNCiHGNC:16629. RAPGEF3.

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000079337.

PTM / Processingi

Proteomic databases

PaxDbiF8W0N0.
PeptideAtlasiF8W0N0.
PRIDEiF8W0N0.

Expressioni

Gene expression databases

BgeeiENSG00000079337.
ExpressionAtlasiF8W0N0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliF8W0N0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini74 – 144DEPInterPro annotationAdd BLAST71

Phylogenomic databases

eggNOGiKOG2378. Eukaryota.
ENOG410XPX9. LUCA.
GeneTreeiENSGT00880000137870.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000591. DEP_dom.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00610. DEP. 1 hit.
SMARTiView protein in SMART
SM00049. DEP. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
PROSITEiView protein in PROSITE
PS50186. DEP. 1 hit.

Sequencei

Sequence statusi: Fragment.

F8W0N0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLRRMHRPR SCSYQLLLEH QRPSCIQGLR WTPLTNSEES LDFSESLEQA
60 70 80 90 100
STERVLRAGR QLHRHLLATC PNLIRDRKYH LRLYRQCCSG RELVDGILAL
110 120 130 140 150
GLGVHSRSQV VGICQVLLDE GALCHVKHDW AFQDRDAQFY RFPGPEPEPV
160 170 180 190 200
RTHEMEEELA EAVALLSQRG PDALLTVALR KPPGQRTDEE LDLIFEELLH
210 220
IKAVAHLSNS VKRELAAVLL FE
Length:222
Mass (Da):25,426
Last modified:October 5, 2016 - v8
Checksum:i420E4EBFEEE749EF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei222Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004241 Genomic DNA. No translation available.
AC137054 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000466322; ENSP00000446731; ENSG00000079337.
UCSCiuc058nbq.1. human.

Similar proteinsi

Entry informationi

Entry nameiF8W0N0_HUMAN
AccessioniPrimary (citable) accession number: F8W0N0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: October 5, 2016
Last modified: October 25, 2017
This is version 52 of the entry and version 8 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported